Sudden Grayish Ovals in Vision: Possible Causes and Concerns - Ophthalmology

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A sudden appearance of a flat oval-shaped "mosaic/ground glass" grayish-white shadow in the right eye?


Hello Doctor: My left eye is hyperopic at +2.25 diopters, and my right eye is myopic at -6.25 diopters.
Due to severe astigmatism in my left eye, I have some amblyopia and primarily rely on my right eye for vision.
A year and a half ago, I discovered that my intraocular pressure was very high, and I have since been regularly visiting a clinic to obtain eye drops (Tafluprost) to manage my eye pressure.
In April of this year, during an examination at a regional hospital, it was noted that the optic nerves in both eyes were slightly thinner at the top, and there was a minor congenital cataract, but neither condition affected my vision.
The doctor indicated that I should continue to be monitored.
During a follow-up appointment on July 15, my condition remained unchanged, with an intraocular pressure of 22 mmHg before accounting for corneal thickness and 19 mmHg after.
However, on July 18 during the day, I felt a foreign body sensation in my right eye, so I rubbed it, which led to a sharp pain near the eye socket, but it resolved shortly after.
In the afternoon, I suddenly experienced a bit of dizziness (which occurs about once every 1-2 months), lasting less than 3 minutes before subsiding.

On the night of July 18 at 11 PM, I suddenly noticed a flat, oval-shaped grayish-white shadow in the upper right part of my central vision (not covering the central vision).
It resembled a mosaic or frosted glass effect, creating a grayish-white overlay in my field of vision.
The area was not very large, and it moved with my eye movements; I could also see it when my eyes were still.
It did not disappear temporarily with eye movements or relaxation.
When reading, it obscured the upper right part of the next one or two characters, making the letter "O" appear like a "C" with a gap in the upper right, and the horizontal line above the character "二" was reduced to just a small portion on the left.
In bright outdoor light, when looking at white lines on the ground, the shadow appeared grayish-black or gray-brown, and when looking at the blue sky, it also appeared grayish-black or gray-brown.

On the morning of July 19, I visited an ophthalmology clinic, where my intraocular pressure was measured at 22 mmHg (not accounting for corneal thickness).
I underwent fundus photography and dilated fundus examination, and the clinic doctor reported no signs of inflammation, with no issues found in the retina, optic nerve, or macula.
I was also not informed of any vitreous opacities or floaters, and the doctor suggested that if I wanted a detailed assessment, I should go to a larger hospital, providing me with a referral and advising me to observe for a few days.

In the afternoon of July 19, I visited the ophthalmologist at the regional hospital I had previously seen.
After a dilated fundus examination, the doctor checked every corner of my eye but found no issues.
I was then scheduled for an OCT scan and noticed that the shadow was more pronounced when I focused on the central red cross of the instrument, closely adjacent to the upper right area of the cross (very close to the center).
After carefully reviewing the OCT images, the regional hospital doctor confirmed that my macula showed no edema or lesions, the retina and optic nerve were normal, and there were no white spots or signs of inflammation.
The doctor noted that the vitreous might "suspect" some opacities and advised me to observe for a week before returning for a follow-up, with the diagnosis recorded as ocular hypertension, without mentioning any vitreous opacities.

In the past six months, I have been going to bed very late (but I usually get about 8 hours of sleep), and I have been using my eyes more than usual.
I have speculated whether this could simply be eye fatigue or floaters, but this condition has persisted for a full two days now.
If it were eye fatigue, it shouldn't last this long, and the grayish-white/gray-black shadow I see is different from typical floater symptoms.
If it were floaters, both doctors should have directly informed me of that after the dilated fundus examination, and the regional hospital doctor did not record it as vitreous opacities, only suggesting to observe for a week before considering a referral to a neurologist.

I primarily rely on my right eye for vision, and now I am suddenly troubled and worried by an unexplained grayish-white/gray-black shadow in that eye.
Last night, I researched some cases and found a case report from Taipei City Hospital where a patient had similar complaints and was ultimately diagnosed with "posterior vitreous detachment." However, since the regional hospital performed an OCT scan, they should have been able to identify that condition as well.

My questions are as follows:
1.
Have you encountered similar cases before? What is the most likely cause of this condition?
2.
Is it possible that there is an issue with the pre-macular bursa? If there is a problem in that area, can an ophthalmologist detect it through examination?
3.
Could this be related to a neurological issue in the brain?
Thank you, Doctor.

Mr. N, 20~29 year old female. Ask Date: 2021/07/20

Dr. Gao Pilin reply Ophthalmology


Hello Mr.
N: If you notice movement that follows your eye movements but is slightly out of sync and appears shaky, it is likely due to opacities in the vitreous body.
These opacities can sometimes be undetectable during examinations and are only perceptible to the individual.
Vitreous detachment may not always be visible unless it is very pronounced or if a Weiss ring is present.
Any issues in the macular region should be detectable via OCT.
If necessary, the physician may arrange for a visual field test to check for any potential brain lesions.
Information found online should only be used as a reference; it is essential to seek medical attention at a healthcare facility if needed.
Gao Pilin

Reply Date: 2021/07/20

More Info


Your situation is indeed concerning, and it’s understandable that you are feeling anxious about the sudden appearance of grayish ovals in your vision. Based on your description, it seems you are experiencing a phenomenon that could be related to several potential causes, particularly given your history of high myopia and other eye conditions.

1. Possible Causes of Grayish Ovals: The grayish ovals you are seeing could be attributed to several factors. One common cause in individuals with high myopia is vitreous detachment. As we age or in cases of high myopia, the vitreous gel inside the eye can begin to liquefy and pull away from the retina, which can lead to visual disturbances such as floaters or shadows. This might explain the grayish or hazy appearance you are experiencing. Additionally, posterior vitreous detachment (PVD) can occur, which may not always be visible on standard OCT scans, especially in the early stages.

2. Macular Issues: You mentioned concerns about the macular area. While your recent examinations did not indicate any macular edema or lesions, it is still possible for subtle changes to occur that might not be easily detected without specialized imaging. Conditions such as macular pucker or epiretinal membranes can cause visual distortions and might not be immediately apparent on routine examinations. If there is a suspicion of macular involvement, further imaging such as fluorescein angiography might be warranted.

3. Neurological Considerations: Given your symptoms of dizziness and the visual disturbances, it is prudent to consider whether there could be a neurological component. While your eye examinations have not indicated any issues, visual disturbances can sometimes be linked to neurological conditions, including migraine-associated visual phenomena or even more serious conditions affecting the optic nerve or brain. If your symptoms persist or worsen, a referral to a neurologist for further evaluation may be appropriate.

4. Eye Fatigue and Stress: You mentioned increased screen time and late nights, which can contribute to eye strain or fatigue. While this typically does not cause the specific symptoms you describe, it can exacerbate existing conditions or make you more aware of visual disturbances. Ensuring you take regular breaks from screens and practice good eye hygiene can help alleviate some discomfort.

5. Follow-Up and Monitoring: It is crucial to continue monitoring your symptoms closely. Since your eye care providers have recommended observation, it is essential to adhere to their advice. If the grayish ovals persist, change in appearance, or if you experience any new symptoms such as flashes of light, significant vision loss, or increased pain, you should seek immediate medical attention.

In conclusion, while your recent examinations have not revealed any significant issues, the combination of high myopia, potential vitreous changes, and your symptoms warrants careful monitoring. If your symptoms do not improve or if you have any further concerns, do not hesitate to seek a second opinion or further evaluation from a specialist. Your vision is vital, and ensuring its health is paramount.

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