Your Child's EGFR Results: What Does 172.8 Mean? - Internal Medicine

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Testing issues


Hello, doctor.
I would like to ask you about my child's recent test report, which shows an EGFR of 172.8.
Is this a good result? The report indicates this value in red, and I am feeling a bit anxious.
Could you please clarify this for me? Thank you.

Xiao Wei, 40~49 year old female. Ask Date: 2021/07/21

Dr. Hong Yuanbin reply Internal Medicine


Hello, eGFR is calculated based on the kidney index: creatinine levels to estimate the glomerular filtration rate.
If it is below 60, caution is advised; if it falls below 10, there is a risk that dialysis may be needed.
Young individuals typically have levels above 100, which is normal and not a cause for concern.
Thank you for your question.

Reply Date: 2021/07/21

More Info


Understanding your child's eGFR (estimated Glomerular Filtration Rate) result is crucial for assessing kidney function. An eGFR of 172.8 mL/min/1.73 m² is indeed a very high value, especially when considering that normal eGFR values for children typically range from 90 to 120 mL/min/1.73 m², depending on age, sex, and body surface area.
The eGFR is a calculated value that estimates how well the kidneys are filtering waste from the blood. It is derived from serum creatinine levels, age, sex, and race. In children, a higher eGFR can indicate that the kidneys are functioning well, as they are generally expected to have higher filtration rates compared to adults. Values above 120 mL/min/1.73 m² can sometimes be seen in very young children or in those who are very physically active.

However, the red flag in your report might be due to the fact that eGFR values are typically not expected to exceed 150 mL/min/1.73 m² in clinical practice. A value of 172.8 could suggest a few things. It might indicate an overestimation due to a lower serum creatinine level, or it could be a result of the child's hydration status at the time of testing. If the child was very well-hydrated, this could lead to a higher eGFR reading.
It's important to note that while a high eGFR is generally a good sign of kidney function, it should be interpreted in the context of the child's overall health, any symptoms they may be experiencing, and other laboratory results. If there are no accompanying symptoms such as swelling, changes in urine output, or other signs of kidney issues, it is likely that this high eGFR is not a cause for concern.

In cases where eGFR is significantly elevated, doctors may recommend retesting to confirm the result, especially if there are any concerns about kidney function or if the child has any underlying health conditions. It is also essential to consider other kidney function markers, such as urine protein levels, to get a complete picture of kidney health.

In summary, an eGFR of 172.8 mL/min/1.73 m² is unusually high and should be discussed further with your child's healthcare provider. They may suggest additional tests or monitoring to ensure that your child's kidneys are functioning properly and to rule out any potential issues. Always feel free to ask your healthcare provider for clarification on any test results that cause concern, as they can provide the most personalized and accurate information based on your child's health history and current condition.

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