Elevated fasting blood glucose with normal glycated hemoglobin (prediabetes)?
Hello, Doctor.
During my health check-up last year, my fasting blood sugar was found to be 110, so I started paying attention to my diet and exercise.
My weight, which was originally 173 lbs at 77 kg, has decreased to 173 lbs at 63 kg after 3-4 months.
However, during my follow-up blood tests every three months over the past 10 months, my fasting blood sugar has consistently been elevated at 112, 104, and 100.
Nevertheless, my hemoglobin A1c levels have remained normal at 5.2, 5.7, and 5.3.
I would like to ask the doctor:
1.
Is there still a chance to reverse my fasting blood sugar levels? It has been 10 months since I first detected elevated fasting blood sugar, but it still remains high.
2.
Currently, aside from my three meals, I hardly consume any desserts or eat out.
However, I often feel hungry at night after dinner at 7 PM and sometimes drink unsweetened soy milk or skip eating before going to bed at midnight.
Will this significantly impact my fasting blood sugar test results?
3.
If I want to take supplements, is bitter melon peptide safe to use for maintenance? Is there a possibility it could harm my kidneys?
Thank you very much for your thoughtful answers, Doctor!
Peter, 30~39 year old female. Ask Date: 2021/07/27
Dr. Xiao Yongxun reply Family Medicine
Dear Mr.
Peter:
1.
Generally speaking, a normal fasting plasma glucose level is less than 100 mg/dL.
If the level is between 100 mg/dL and 126 mg/dL, it can be considered as prediabetes or impaired fasting glucose.
Of course, if the fasting glucose is greater than or equal to 126 mg/dL, diabetes should be suspected.
2.
Your fasting glucose levels were 112, 104, and 100 mg/dL; however, your hemoglobin A1c levels are normal, which may indicate mild impaired fasting glucose.
This is often due to overeating recently or lack of exercise.
In fact, if there are family members with diabetes, individuals who are obese, those with a history of gestational diabetes, women who have given birth to infants weighing over 4 kg, individuals with hyperlipidemia, hypertension, unexplained weight loss, or wounds that do not heal easily, they all have an increased risk of diabetes.
If none of these apply to you, there is no need to panic.
Increasing physical activity, reducing the intake of refined foods, especially avoiding overeating and high glycemic index foods, getting enough sleep, and moderate weight loss can improve blood glucose levels.
Mild diabetes can improve to impaired glucose tolerance; impaired glucose tolerance can improve to normal.
This means that the development of diabetes is not an all-or-nothing phenomenon or something that happens suddenly; it is progressive.
Therefore, it is essential to consistently change lifestyle, dietary habits, and maintain regular exercise.
3.
You mentioned that you often feel hungry at midnight and sometimes drink unsweetened soy milk.
In fact, unsweetened soy milk also contains calories, and if consumed without burning off the calories, it may still affect your morning fasting glucose levels.
4.
Bitter melon peptides are considered a health supplement and are generally safe as long as they are not consumed in excess.
However, there is a lack of rigorous research reports on their effectiveness in controlling blood glucose levels, so high expectations should be avoided.
5.
Regarding practical measures for diabetes prevention, I personally recommend that you chew your food well during meals, avoid overeating (aim for 80% fullness), and limit high-calorie, high-fat, and high-sugar foods or beverages.
Reduce the intake of high-cholesterol and trans fats (often found in creamers, butter, ghee, instant coffee, milk tea, etc.) and high fructose corn syrup (commonly found in commercial beverages, desserts, sodas, pastries, etc.).
These types of foods may be harder for the body to metabolize, may contain calories without providing a sense of fullness, and can easily lead to elevated blood glucose levels.
On the other hand, develop a regular exercise routine, such as playing sports, jogging, swimming, or cycling.
In fact, taking a good walk for 30-60 minutes after each meal can be very effective.
In terms of daily living, avoid excessive stress and ensure sufficient sleep; this will reduce the secretion of related hyperglycemic hormones and increase the secretion of leptin, which helps with weight control.
Additionally, based on personal observation, it is advisable to avoid excessive cold drinks or ice water and to keep air conditioning at a moderate temperature, as this can lead to increased hunger and overeating.
6.
If you have further questions, please discuss them with your family physician for a decision, or visit the outpatient department of a regional hospital's metabolism clinic for medical care.
Reply Date: 2021/07/27
More Info
Managing high fasting blood sugar levels while maintaining a normal HbA1c can be a challenging situation, especially for individuals who are actively trying to improve their health through diet and exercise. Your case presents a common scenario where fasting blood sugar levels remain elevated despite efforts to manage weight and dietary intake. Let's address your questions one by one.
1. Can fasting blood sugar levels still be reversed?
Yes, there is still an opportunity to reverse high fasting blood sugar levels. Fasting blood sugar levels can be influenced by various factors, including diet, physical activity, stress, and sleep patterns. Since you have already made significant lifestyle changes, such as weight loss and increased physical activity, it is essential to continue these efforts. However, it may also be beneficial to assess your overall dietary habits. For instance, consider the timing and composition of your meals. Eating a balanced diet rich in whole grains, lean proteins, healthy fats, and plenty of vegetables can help stabilize blood sugar levels. Additionally, incorporating regular physical activity, such as aerobic exercises and strength training, can improve insulin sensitivity and help lower fasting blood sugar levels.
2. Does late-night snacking affect fasting blood sugar?
Yes, late-night snacking can significantly impact fasting blood sugar levels. Eating close to bedtime can lead to elevated blood sugar levels in the morning, especially if the snacks are high in carbohydrates. If you find yourself hungry at night, consider healthier options that are lower in carbohydrates and higher in protein or fiber, such as a small serving of nuts or Greek yogurt. Drinking unsweetened soy milk is a better choice than sugary snacks, but it’s still important to monitor portion sizes. Ideally, try to finish eating at least two to three hours before bedtime to allow your body to process the food and stabilize blood sugar levels overnight.
3. Is it safe to take bitter melon peptides as a supplement?
Bitter melon (Momordica charantia) is often touted for its potential benefits in managing blood sugar levels. Bitter melon extracts and peptides may help improve insulin sensitivity and lower blood sugar levels. However, it is crucial to approach any supplement with caution, especially if you have existing health conditions or are taking medications. While bitter melon is generally considered safe for most people, it can interact with certain medications, particularly those for diabetes, and may affect kidney function in high doses. Therefore, it is advisable to consult with your healthcare provider before starting any new supplement, including bitter melon peptides, to ensure it is appropriate for your specific health situation.
In summary, while your fasting blood sugar levels are elevated, there are still effective strategies to manage and potentially reverse this condition. Focus on maintaining a balanced diet, regular exercise, and mindful eating habits. Additionally, consult with your healthcare provider regarding any supplements you wish to take, and consider regular monitoring of your blood sugar levels to track your progress. With continued effort and professional guidance, you can work towards achieving better blood sugar control.
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