Concerns About Estrogen Use During Pregnancy Planning: What You Need to Know

Issues with Estrogen Administration

Hello, Doctor.
My last menstrual period was from July 20 to July 26.
However, on the morning of August 5, I noticed brown spotting that continued into the evening, so I decided to visit a clinic.
The doctor performed an abdominal ultrasound and said that I had not yet ovulated, ruling out ovulatory bleeding.
They also mentioned seeing a 1.3 mm immature follicle and advised me to wait.
I was diagnosed with hormonal imbalance and prescribed a 3-day course of Estromon (Premarin) 0.625 mg and hemostatic medication.
I asked the doctor if it was safe to conceive while taking these medications, and they said it was fine.
However, after returning home and researching, I found that Estromon (Premarin) can cause fetal malformations.
I have already taken two pills, so I would like to know if I should avoid trying to conceive this month.
Thank you for your response!

WINNI, 30~39 year old female. Ask Date: 2021/08/06

Dr. Chen Zhiyu reply Obstetrics and Gynecology

Regarding your concerns, the medication prescribed is commonly used in general obstetrics and gynecology to manage abnormal vaginal bleeding.
It is indeed a hormonal medication, and such medications are typically used with caution when pregnancy is confirmed.
If you have already expressed your concerns to your physician and received a reassuring response, it indicates that your trusted physician has given considerable thought and confidence to the situation.
Nevertheless, if you still have worries, it is advisable to consult again with the prescribing physician for further discussion.
Thank you for your inquiry, and I wish you health and happiness.

Reply Date: 2021/08/06

More Info

When considering the use of estrogen medications like Estromon (Premarin) during pregnancy planning, it is essential to understand both the medication's purpose and its potential effects on fertility and fetal development. Estromon is a form of conjugated estrogen, primarily used to treat hormonal imbalances, such as those that can cause irregular menstrual cycles or other symptoms of estrogen deficiency.

In your case, you mentioned that you experienced some unusual bleeding and were diagnosed with hormonal imbalance. Your doctor prescribed Estromon to help regulate your hormones and potentially prepare your body for pregnancy. It is important to note that the use of estrogen in the context of preparing for pregnancy is not uncommon, especially when hormonal imbalances are present. The medication can help to stabilize the uterine lining and promote a more conducive environment for conception.

Regarding your concerns about the potential risks of Estromon leading to fetal abnormalities, it is crucial to clarify that the use of estrogen during the early stages of pregnancy is a topic of ongoing research. While some studies have raised concerns about the use of certain hormonal medications during pregnancy, the consensus among many healthcare professionals is that when used appropriately and under medical supervision, the risks can be managed effectively.

The key points to consider are:
1. Timing of Use: If you are actively trying to conceive, it is essential to communicate openly with your healthcare provider about your plans. If you have already started taking Estromon, it is advisable to discuss with your doctor whether you should continue or adjust your medication based on your current cycle and ovulation status.

2. Potential Risks: While there are concerns regarding the use of certain medications during pregnancy, Estromon is classified as a Category X medication when used inappropriately during pregnancy. However, if taken under the guidance of a physician for a specific medical condition prior to conception, the risks may be minimized. It is essential to follow your doctor's advice regarding the timing and dosage of any medication.

3. Monitoring and Follow-Up: If you have taken Estromon and are concerned about its effects on a potential pregnancy, your doctor may recommend monitoring your hormone levels and overall reproductive health. This can help ensure that any potential issues are identified early and managed appropriately.

4. Consultation with Specialists: If you have ongoing concerns about the effects of hormonal medications on pregnancy, consider seeking a consultation with a reproductive endocrinologist or a fertility specialist. They can provide tailored advice based on your specific health history and fertility goals.

In summary, while it is understandable to have concerns about the use of estrogen medications during pregnancy planning, it is essential to rely on the guidance of your healthcare provider. They can help you weigh the benefits and risks of continuing your medication while trying to conceive. If you have already taken two doses of Estromon, it is best to discuss your next steps with your doctor, who can provide personalized recommendations based on your health status and fertility plans. Remember, open communication with your healthcare provider is key to ensuring a safe and healthy approach to pregnancy planning.

Similar Q&A

Hormone Therapy for Transgender Women: Risks and Effects of Estrogen Use

Hello Dr. Chang, I was diagnosed as a transgender woman with gender dysphoria by a psychiatrist earlier this year, and I recently started hormone therapy. My gynecologist prescribed a four-week course of oral Estromon F.C. tablets. I would like to ask if there are any adverse eff...

Dr. Zhang Kunmin reply Obstetrics and Gynecology
Hello, based on your situation and considering the safety of the fetus and the stability of the uterus, it is recommended to follow your doctor's advice, continue taking the medication, and attend regular prenatal check-ups. Thank you! Wishing you safety and health. Dr. Zhan...

Does Taking Estrogen Affect My Chances of Getting Pregnant?

I started my period on November 30, and then again on December 21. In January and February, my period came regularly on the 23rd, but the flow was lighter than before, and by the third day of my February period, there was hardly any bleeding. I visited a hospital, and the doctor ...

Dr. Lü Lizheng reply Obstetrics and Gynecology
1. Taking Eisted should not affect future pregnancies. 2. Maintaining a healthy state through balanced sleep, diet, and exercise should make it easier to conceive. It is also advisable to consult a fertility specialist. Sincerely, Dr. Lu Li-Cheng, Taoyuan Hospital.

Concerns About Female Fetal Masculinization After Medication Use

Hello Doctor, I am about 5 weeks pregnant. On April 15th, I unknowingly took medication (NORETHINDONE ACET - oral, three times a day for 3 days, 2 tablets each time; TABSCANOL - oral, three times a day for 3 days, 1 tablet each time). However, I did not finish the course and onl...

Dr. Chen Changfu reply Obstetrics and Gynecology
Recent ultrasound examination estimates that the fetus is approximately 5 weeks old. On April 15 (about 3 weeks ago), norethindrone acetate (a progestin) was taken. Based on the gestational age, the medication was likely taken around the time of ovulation and fertilization. Altho...

Medication Considerations Before Pregnancy: What You Need to Know

Hello, Doctor. I have a pregnancy plan. I underwent an outpatient procedure to remove colon polyps on August 25 and was prescribed medication for one week. My menstrual period started on August 25, so I would like to ask if I should avoid pregnancy next month or if I can continue...

Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, those medications generally do not have an impact, so you should be able to continue with your pregnancy plans. Wishing you good health.