Medication Considerations Before Pregnancy: What You Need to Know - Obstetrics and Gynecology

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Medications Before Pregnancy


Hello, Doctor.
I have a pregnancy plan.
I underwent an outpatient procedure to remove colon polyps on August 25 and was prescribed medication for one week.
My menstrual period started on August 25, so I would like to ask if I should avoid pregnancy next month or if I can continue with my pregnancy plan.
Here are the medications I am taking: pinaverium for intestinal relaxation, scopolamine (10 mg) for gastrointestinal spasms, simethicone for gastrointestinal bloating, astaxanthin for fatigue relief, tranexamic acid (250 mg) for hemostasis and inflammation, L-S Vitamin C for ascorbic acid, Xymol suppository (400 mg), and alprazolam (0.25 mg) for hemorrhoid relief and autonomic nervous system regulation.

Wen, 30~39 year old female. Ask Date: 2015/08/29

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, those medications generally do not have an impact, so you should be able to continue with your pregnancy plans.
Wishing you good health.

Reply Date: 2015/08/29

More Info


When considering pregnancy, it is crucial to be aware of the medications you are taking and their potential effects on both fertility and fetal development. Based on the medications you mentioned—pinaverium, scopolamine, simethicone, astaxanthin, tranexamic acid, vitamin C, Xymol suppositories, and alprazolam—let's break down their implications for your pregnancy plans.

1. Pinaverium: This medication is an antispasmodic used to relieve gastrointestinal spasms. It is generally considered safe during pregnancy, but as with any medication, it should be used under the guidance of a healthcare provider.

2. Scopolamine (10mg): Scopolamine is often used to treat motion sickness and nausea. It is classified as a Category C drug, meaning that animal studies have shown an adverse effect on the fetus, but there are no adequate studies in humans. It is advisable to consult your doctor regarding its use if you are planning to conceive.

3. Simethicone: This medication is commonly used to relieve bloating and discomfort caused by excess gas. It is considered safe during pregnancy and is often recommended for pregnant women experiencing gas-related discomfort.

4. Astaxanthin: This is a dietary supplement known for its antioxidant properties. While there is limited research on its safety during pregnancy, it is generally considered safe in moderate amounts. However, it is always best to consult with a healthcare provider before taking any supplements while trying to conceive.

5. Tranexamic Acid (250mg): This medication is used to reduce bleeding. It is classified as Category B, indicating that it has not been shown to cause harm to the fetus in animal studies. However, its use during pregnancy should still be discussed with your healthcare provider.

6. Vitamin C (Ascorbic Acid): Vitamin C is essential for health and is generally considered safe during pregnancy. It is important for the immune system and overall health, but excessive doses should be avoided.

7. Xymol Suppositories (400mg): The safety of this medication during pregnancy is not well established. It is essential to consult with your healthcare provider regarding its use.

8. Alprazolam (0.25mg): This medication is a benzodiazepine used for anxiety and panic disorders. It is classified as Category D, meaning there is evidence of risk to the fetus based on human data. It is generally advised to avoid benzodiazepines during pregnancy due to potential risks, including withdrawal symptoms in newborns and other complications.

Given that you had a polyp removal procedure on August 25 and your menstrual cycle started on the same day, it is advisable to wait until you have completed your course of medications and have consulted with your healthcare provider before actively trying to conceive. The timing of your menstrual cycle and the medications you are taking could influence your fertility and the health of a potential pregnancy.

In summary, while some of the medications you are taking are considered relatively safe, others, particularly alprazolam, pose potential risks during pregnancy. It is essential to have a thorough discussion with your healthcare provider about your medication regimen, any necessary adjustments, and the best timing for your pregnancy plans. They can provide personalized advice based on your health history and the specifics of your situation. Always prioritize open communication with your healthcare team to ensure the best outcomes for both you and your future baby.

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