Persistent Cough: Causes and Treatment Options - Pulmonology

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Coughing for a long time?


Hello, Doctor: I caught a cold around October last year and have been coughing for over a month.
I later visited a pulmonologist, who performed an X-ray and pulmonary function tests.
Initially, I took cough suppressants and expectorants, but my cough did not improve.
The doctor then prescribed a dry powder inhaler, which provided significant relief immediately.
The doctor mentioned that I might have asthma.
I have been using the inhaler for the past 7 to 8 months, and my condition was well controlled.
However, last month, I suddenly started coughing again, and it has been almost a month.
The doctor switched my medication to a bronchodilator, and I am currently on the second day of use, but there hasn't been much improvement.
My family believes that my cough might be caused by gastroesophageal reflux disease (GERD).
Could you please advise what might be the underlying cause of my symptoms?

Han, 20~29 year old female. Ask Date: 2021/08/21

Dr. Yang Wenda reply Pulmonology


Hello Han: Based on the previous improvement with the inhaler, the physician's diagnosis of asthma seems accurate.
However, asthma patients can still experience acute exacerbations due to factors such as colds, exposure to allergens (like dust mites or pollen), significant temperature changes, or gastroesophageal reflux.
It is recommended to continue using the bronchodilator along with medications to suppress gastric acid, which should help improve the condition.
As for the possibility of gastroesophageal reflux, a gastroscopy is necessary for diagnosis.

Reply Date: 2021/08/21

More Info


Persistent cough can be a frustrating and debilitating symptom, often indicating an underlying condition that requires careful evaluation and management. Based on your description, it seems that your cough has been ongoing for several months, with a history of asthma and recent changes in treatment. Let’s break down the potential causes and treatment options for your persistent cough.


Possible Causes of Persistent Cough
1. Asthma: Given your previous diagnosis and the improvement you experienced with the inhaler, it’s possible that your cough is related to asthma. Asthma can cause chronic cough, especially if it is not well-controlled. Symptoms may include wheezing, chest tightness, and difficulty breathing, particularly at night or during exercise.

2. Gastroesophageal Reflux Disease (GERD): Your family’s suggestion about GERD is also worth considering. GERD can lead to chronic cough due to acid irritating the throat and airways. Symptoms may include heartburn, regurgitation, and a sour taste in the mouth. Coughing may worsen after meals or when lying down.

3. Postnasal Drip: This occurs when mucus from the sinuses drips down the back of the throat, triggering a cough reflex. It can be associated with allergies, sinus infections, or colds. Symptoms may include a runny or congested nose, throat clearing, and a sensation of mucus in the throat.

4. Chronic Bronchitis: This condition, often related to smoking or long-term exposure to irritants, can cause a persistent cough with mucus production. It is characterized by inflammation of the bronchial tubes.

5. Infections: While you mentioned that your cough has persisted for months, it’s important to rule out any lingering infections, such as a bacterial infection that may require antibiotics.

6. Other Conditions: Other less common causes include interstitial lung disease, lung cancer, or heart failure. These conditions would typically present with additional symptoms and would require further investigation.


Treatment Options
1. Asthma Management: If asthma is confirmed as the cause, ensure that you are using your inhaler correctly and consistently. Long-term control medications, such as inhaled corticosteroids, may be necessary. If your symptoms are not well-controlled, a healthcare provider may consider adjusting your medication regimen.

2. GERD Management: If GERD is suspected, lifestyle modifications such as avoiding trigger foods (spicy, fatty, or acidic foods), eating smaller meals, and not lying down immediately after eating can be beneficial. Over-the-counter antacids or prescription medications may also help reduce acid production.

3. Postnasal Drip Treatment: If postnasal drip is the culprit, antihistamines or nasal corticosteroids can help reduce mucus production. Staying hydrated and using saline nasal sprays may also provide relief.

4. Infection Treatment: If a bacterial infection is suspected, a healthcare provider may prescribe antibiotics. It’s essential to complete the full course of antibiotics if prescribed.

5. Further Evaluation: Since your cough has persisted despite treatment, it may be beneficial to return to your healthcare provider for further evaluation. This may include additional tests such as a CT scan of the chest, allergy testing, or a referral to a gastroenterologist if GERD is suspected.


Conclusion
In summary, persistent cough can arise from various causes, including asthma, GERD, postnasal drip, chronic bronchitis, and infections. Given your history and ongoing symptoms, it’s crucial to work closely with your healthcare provider to determine the underlying cause and appropriate treatment. Keeping a symptom diary, noting when the cough worsens, and any associated symptoms can also provide valuable information for your healthcare provider. Remember, effective management often requires a comprehensive approach tailored to your specific situation.

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