Post-Vaccine Medication: Can I Take Ibuprofen for Fever? - Internal Medicine

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Vaccine administration?


Hello Dr.
Hong, I would like to ask about the medication I received after getting vaccinated this morning.
The clinic gave me three yellow tablets of Paracetamol, and I have already taken one.
However, I suddenly remembered that a few days ago, another doctor prescribed me Ibuprofen 400mg, which is pink.
If I develop a fever, can I take the Ibuprofen, or should I just stick with the yellow tablets?
Additionally, I am experiencing some discomfort in my chest when I take deep breaths or turn my body, which feels slightly painful.
Is this normal? Currently, I do not have any difficulty breathing, rapid heartbeat, or signs of thrombosis, so should I not be overly concerned? The more I think about it, the more I feel something might be off.
I apologize for bothering you at night, and thank you for your help.

Xing, 20~29 year old female. Ask Date: 2021/09/10

Dr. Hong Yuanbin reply Internal Medicine


Hello, Paracetamol, commonly known as acetaminophen, has a slightly weaker analgesic effect.
However, due to its lower side effects, it can be used first for fever or pain.
Ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), has a stronger analgesic and antipyretic effect, but it also has a higher risk of causing stomach pain or kidney function issues.
It is recommended to use acetaminophen first, and if fever or pain persists and becomes unbearable, then consider using the chest expansion or movement you mentioned.
These symptoms could be potential side effects of the vaccine, but currently, there is no need for concern.
Thank you for your question.

Reply Date: 2021/09/10

More Info


After receiving a vaccine, it's common to experience mild side effects, including fever, soreness, and general discomfort. In your case, you have been prescribed acetaminophen (commonly known as Tylenol or Panadol) and are considering whether to take ibuprofen as well.
Both acetaminophen and ibuprofen are effective for reducing fever and alleviating pain, but they work in slightly different ways. Acetaminophen is generally considered safer for most people and has fewer gastrointestinal side effects compared to ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen can be more effective for inflammation-related pain but may cause stomach upset or other gastrointestinal issues in some individuals.
If you have already taken one dose of acetaminophen and are still experiencing fever or significant discomfort, it is generally safe to take ibuprofen as long as you follow the recommended dosage guidelines. However, it is essential to avoid exceeding the maximum daily dose of either medication. Alternating between acetaminophen and ibuprofen can also be an effective strategy for managing fever and pain, but you should space out the doses appropriately.

Regarding your concerns about chest discomfort and soreness when moving or taking deep breaths, these symptoms can be common after vaccination. The vaccine can trigger an immune response, leading to localized inflammation and muscle soreness, which may manifest as discomfort in the chest area. As long as you are not experiencing severe symptoms such as difficulty breathing, rapid heart rate, or signs of a blood clot (like swelling or pain in one leg), it is likely that these sensations are normal and related to the vaccine's effects on your body.

It's important to monitor your symptoms closely. If the discomfort worsens or if you develop new symptoms, such as significant shortness of breath, persistent chest pain, or any other concerning signs, you should seek medical attention promptly. Anxiety about symptoms can sometimes amplify the perception of discomfort, so try to stay calm and focus on managing your fever and pain as needed.

In summary, you can take ibuprofen for fever after receiving the vaccine, especially if acetaminophen alone is not providing sufficient relief. Just be mindful of the dosages and any potential side effects. As for the chest discomfort, it is likely a normal reaction to the vaccine, but keep an eye on your symptoms and consult a healthcare professional if you have any concerns. Your health and well-being are important, and it's always better to err on the side of caution when it comes to your health.

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