Unexplained Chest Pain After Drug-Eluting Stent: A Sleep Disruption Dilemma - Cardiology

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Unexplained chest pain after the completion of a drug-eluting stent procedure, leading to an inability to sleep?


The patient is a 55-year-old female who, two months after undergoing coronary catheterization with drug-eluting stent placement, continues to experience unexplained chest pain that prevents her from sleeping.
She has been adhering to her postoperative medication regimen.
Last month, she was taking antihypertensive medication (Amlodipine), with blood pressure readings around 120-130/80 mmHg.
This month, she switched to Carvedilol and Concor 1.25 mg, with blood pressure readings between 125-145/85 mmHg.
The chest pain at night has not improved, and she frequently experiences discomfort (a sensation of foreign body in the heart, increased heart rate, and severe pain).
She has noticed that taking an extra tablet of Carvedilol and Concor at night seems to provide some relief.
She would like to ask the doctor if this medication adjustment is safe.
Additionally, two weeks post-surgery, her blood pressure spiked to 180/85 mmHg, prompting an emergency room visit due to chest pain that lasted for two days with little sleep.
However, both the electrocardiogram and cardiac enzyme tests indicated no issues, and follow-up examinations one month post-surgery also appeared normal.
After experiencing chest pain at night, her blood pressure and heart rate measurements are similar to those taken before sleep (slightly elevated but within normal limits).
She feels that there are several autonomic nervous system issues following the surgery, but the primary concern is resolving the chest pain to facilitate proper recovery.

Chen Zhi-liang, 20~29 year old female. Ask Date: 2021/09/22

Dr. Li Han reply Cardiology


Hello, there are many causes of chest pain.
The responsibility of a cardiologist is to identify potentially life-threatening chest pain.
This may involve evaluating symptoms or utilizing diagnostic tools such as electrocardiograms, X-rays, stress tests, ultrasounds, or advanced imaging techniques.
Perhaps your family member is suffering from chest pain and some troubling symptoms, but the physician may not have objective evidence to provide a satisfactory answer.
It is advisable to discuss this further with the attending physician, as they may be able to find a solution.
The Ministry of Health and Welfare Changhua Hospital cares about you.

Reply Date: 2021/09/22

More Info


Unexplained chest pain after the placement of a drug-eluting stent can be a concerning issue, especially when it disrupts sleep and affects overall well-being. In your case, it appears that you have been following your post-operative medication regimen, but you are still experiencing significant discomfort, particularly at night. This situation raises several important considerations regarding potential causes, medication interactions, and management strategies.

Firstly, it is essential to understand that chest pain after stent placement can arise from various factors. While the stent itself is designed to keep the artery open and improve blood flow, other issues may contribute to ongoing symptoms. These can include anxiety, which is common after cardiac procedures, or even the development of new cardiac conditions. Additionally, the autonomic nervous system can play a role in how your body responds to stress and pain, which may explain the "foreign body" sensation and increased heart rate you are experiencing.

Regarding your medication regimen, you mentioned that you were initially on a high blood pressure medication (likely a beta-blocker) and then switched to a different combination. It is important to note that beta-blockers can help manage both blood pressure and anxiety, which may be beneficial in your case. However, taking additional doses of your medications (Katyxin and Kankin) without consulting your healthcare provider can lead to potential complications, including hypotension or bradycardia, especially if these medications are also designed to lower blood pressure.

If you find that taking extra doses seems to alleviate your symptoms, it could indicate that your current dosage may not be adequately controlling your blood pressure or anxiety levels. However, self-adjusting your medication can be risky, and it is crucial to discuss this with your physician. They may need to reassess your treatment plan, considering both your blood pressure readings and the persistent chest pain.

In terms of sleep disruption, it is well-documented that pain can significantly impact sleep quality. The anxiety associated with chest pain can further exacerbate this issue, creating a cycle of discomfort and insomnia. Cognitive-behavioral therapy (CBT) for insomnia or relaxation techniques may be beneficial in managing your sleep disturbances. Additionally, ensuring a conducive sleep environment and practicing good sleep hygiene can help improve your overall sleep quality.

Given your history of elevated blood pressure and the episodes of chest pain, it is advisable to follow up with your cardiologist or primary care physician. They may recommend further diagnostic tests, such as a stress test or echocardiogram, to evaluate your heart's function and rule out any underlying issues that may not have been apparent in previous evaluations.

In summary, while it is understandable to seek relief from your symptoms, it is crucial to do so under the guidance of your healthcare provider. They can help you navigate the complexities of your medication regimen, assess the need for adjustments, and explore additional therapeutic options to manage your chest pain and improve your sleep. Your health and safety should always come first, and open communication with your medical team is key to achieving the best outcomes.

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