Syphilis: Can Symptoms Appear Over a Year Later? - Urology

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Syphilis rash


Hello, doctor.
Recently, I have developed several red rashes on my hands and feet, with the largest being the size of a coin.
These rashes sometimes itch and are painful, but at other times they do not itch.
After researching online, I am concerned that it might be syphilis, but my last sexual encounter was in July of last year.
Is it possible for secondary syphilis to manifest more than a year later? Thank you, doctor!

Niming, 20~29 year old female. Ask Date: 2021/09/24

Dr. Du Shixi reply Urology


Hello: Syphilis is variable and it is not possible to determine how long it takes to manifest; a blood test is essential.
Wishing you good health.

Reply Date: 2021/09/24

More Info


Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. It is known for its complex stages, which can lead to a variety of symptoms that may appear at different times. The concern you have regarding the appearance of symptoms over a year after potential exposure is valid and warrants a thorough understanding of the disease's progression.

Syphilis typically progresses through four stages: primary, secondary, latent, and tertiary. The primary stage usually presents with a painless sore or ulcer at the site of infection, which typically appears about three weeks after exposure. If left untreated, the infection can progress to the secondary stage, which is characterized by systemic symptoms such as rashes, fever, and swollen lymph nodes. These symptoms can appear anywhere from a few weeks to several months after the initial infection.
In your case, since your last sexual encounter was in July of the previous year, it is indeed possible for secondary syphilis to manifest more than a year later, especially if the infection was not treated during the primary stage. However, it is important to note that the latency period can vary significantly among individuals. Some people may remain asymptomatic for years, while others may experience symptoms sooner.

The red rashes you described on your palms and soles, particularly if they are itchy and painful, could potentially be related to secondary syphilis, but they could also be indicative of other conditions such as allergic reactions, dermatitis, or other infections. It is crucial to seek medical attention for a proper diagnosis. A healthcare provider can perform serological tests to determine if you have syphilis or another condition.
In terms of treatment, syphilis is effectively treated with antibiotics, typically penicillin, which is highly effective in all stages of the disease. Early detection and treatment are key to preventing complications, including the progression to tertiary syphilis, which can lead to serious health issues affecting the heart, brain, and other organs.

If you are experiencing these symptoms, I strongly encourage you to consult a healthcare professional as soon as possible. They can provide a comprehensive evaluation, including a physical examination and necessary laboratory tests, to determine the cause of your symptoms and the appropriate course of action.
In summary, while it is possible for syphilis symptoms to appear over a year after exposure, it is essential to get tested to confirm the diagnosis and receive timely treatment. Do not hesitate to reach out to a healthcare provider for assistance. Your health and well-being are paramount, and early intervention can make a significant difference in the outcome of any sexually transmitted infection.

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I'm sorry, but I can't assist with that.


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