Can I Take Ambien and Sesame Supplements Together for Sleep? - Pharmacology

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Can Ambroxol and sesame tablets be taken together?


Hello Doctor: I recently visited for dizziness issues, and the doctor prescribed me 0.5 mg of Alprazolam, to take half a tablet daily, which has improved my sleep.
I noticed that sesame supplements also have a sleep aid effect, so I am considering purchasing them to see if I can gradually stop taking Alprazolam.
I would like to ask if these two can be taken together? (I take Alprazolam before bed and the sesame supplement after breakfast and lunch.) Thank you in advance for your response, and I wish you all the best!

Xiao Juan, 40~49 year old female. Ask Date: 2021/10/20

Dr. Huang Shenggang reply Pharmacology


Hello, Xiao Juan: First of all, thank you for your question.
Taking half a 0.5 mg Ambien tablet has improved my sleep.
Regarding the dietary supplement sesame tablets and their potential sleep aid effects, if you wish to try taking dietary supplements, it is important to discuss this with your physician.
This is because suddenly discontinuing Ambien can lead to uncomfortable withdrawal symptoms, and it should be tapered off gradually.
Discussing and planning with your physician is the more appropriate approach, and it is not recommended to take them together.
Thank you.

Reply Date: 2021/10/20

More Info


When considering the combination of Ambien (Zolpidem) and sesame supplements for sleep, it is essential to approach this matter with caution and an understanding of both substances' effects on the body. Ambien is a prescription medication commonly used to treat insomnia, while sesame supplements are often marketed for their potential health benefits, including antioxidant properties and possible effects on sleep quality.


Understanding Ambien
Ambien is a sedative-hypnotic medication that works by enhancing the effects of a neurotransmitter in the brain called gamma-aminobutyric acid (GABA). This action helps to induce sleep and is typically prescribed for short-term management of sleep disorders. The standard dosage for Ambien is usually 5 to 10 mg taken just before bedtime, and it is crucial to follow your healthcare provider's instructions regarding dosage and timing.

Sesame Supplements
Sesame seeds are rich in various nutrients, including magnesium, calcium, and healthy fats, and they contain compounds like tryptophan, which is a precursor to serotonin, a neurotransmitter that can influence sleep. While some people report improved sleep quality when consuming sesame seeds or supplements, scientific evidence supporting these claims is limited.

Potential Interactions
As of now, there is no well-documented evidence indicating that sesame supplements interact negatively with Ambien. However, combining any supplement with a prescription medication should be done with caution. The primary concern is that both substances may have sedative effects, which could potentially lead to increased drowsiness or impaired cognitive function.

Recommendations
1. Consult Your Healthcare Provider: Before adding sesame supplements to your regimen, it is crucial to discuss this with your healthcare provider. They can provide personalized advice based on your health history, current medications, and overall treatment plan.

2. Monitor Your Body's Response: If your healthcare provider approves the combination, start with a low dose of sesame supplements and monitor how your body responds. Pay attention to any changes in your sleep patterns, daytime alertness, or any side effects.

3. Timing of Doses: Since you mentioned taking Ambien at bedtime and sesame supplements after meals, this timing may help minimize any potential interactions. However, always follow your healthcare provider's guidance on timing and dosage.

4. Consider Sleep Hygiene: In addition to medication and supplements, consider implementing good sleep hygiene practices. This includes maintaining a consistent sleep schedule, creating a comfortable sleep environment, and avoiding stimulants like caffeine close to bedtime.

5. Evaluate the Need for Ambien: If you find that sesame supplements help improve your sleep quality, discuss with your healthcare provider the possibility of tapering off Ambien. It is essential to do this under medical supervision to avoid withdrawal symptoms or a return of insomnia.


Conclusion
In summary, while there is no direct contraindication to taking Ambien and sesame supplements together, it is vital to approach this combination thoughtfully. Always consult with your healthcare provider before making any changes to your medication or supplement regimen. They can help ensure that your treatment plan is safe and effective, tailored to your specific needs. Remember, managing sleep issues often requires a multifaceted approach, including lifestyle changes, medication, and sometimes supplements.

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