Can You Take Sleep Medications and B12 Together? Expert Advice - Psychiatry

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Is it necessary to stagger the timing of taking sleep medications and vitamin B12?


Hello, doctor.
My mother is getting older and has been experiencing poor sleep quality in recent years.
During a recent consultation, the doctor prescribed Uledin, which is a sleeping medication.
She has been taking it for a while now.
Recently, a friend recommended that taking B12 can help with sleep and nerve repair.
Could you please advise if Uledin and B12 can be taken together, or if they should be taken at different times? Thank you for your assistance.

shunader, 40~49 year old female. Ask Date: 2023/12/08

Dr. Xue Gengming reply Psychiatry


We recommend that you discuss the above situation further with your attending physician.
Wishing you good health.
Thank you!

Reply Date: 2023/12/08

More Info


When considering the concurrent use of sleep medications like Eurodin (a sedative) and vitamin B12, it's essential to understand both the pharmacological properties of these substances and their potential interactions. Eurodin, which is a brand name for a medication that typically contains the active ingredient zopiclone, is primarily used to treat insomnia by promoting sleep. On the other hand, vitamin B12 (cobalamin) plays a crucial role in nerve function, red blood cell formation, and DNA synthesis. It is often touted for its potential benefits in improving energy levels and possibly aiding in sleep quality, although the latter is less scientifically established.

From a medical perspective, there is generally no known direct interaction between Eurodin and vitamin B12. This means that taking them together is not expected to cause adverse effects or diminish the effectiveness of either substance. However, it is always prudent to consider the overall health context of the individual, especially in older adults who may be taking multiple medications or have underlying health conditions.

In the case of your mother, who is experiencing poor sleep quality and has been prescribed Eurodin, adding vitamin B12 could be beneficial, particularly if she has a deficiency in this vitamin. Vitamin B12 is essential for maintaining healthy nerve cells, and a deficiency can lead to neurological issues, which may indirectly affect sleep quality. However, it is important to note that while B12 can support overall health, it should not be viewed as a primary treatment for insomnia.

Regarding the timing of administration, there is no specific requirement to stagger the intake of Eurodin and vitamin B12. However, it is advisable to take Eurodin as prescribed, typically shortly before bedtime, to maximize its sedative effects. Vitamin B12 can be taken at any time of the day, but some people prefer to take it in the morning to avoid any potential stimulation that might interfere with sleep.
It is crucial to monitor how your mother responds to this combination. If she experiences any unusual symptoms or if her sleep does not improve, it would be wise to consult her healthcare provider. They can provide personalized advice based on her medical history and current medications.
In summary, while Eurodin and vitamin B12 can generally be taken together without significant concerns, it is always best to approach any new supplement or medication with caution, especially in older adults. Regular follow-ups with her healthcare provider will ensure that her treatment plan remains effective and safe.

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