Elevated PSA Levels: Causes and Next Steps for Men - Urology

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Elevated PSA levels?


Hello Doctor, during the company health check-up in September, my PSA level was around 7.
However, the prostate ultrasound, urine tests, and kidney-related tests were all normal.
I have not experienced any unusual urinary symptoms, but I have had persistent lower back pain, which is not related to bone pain.
I would like to ask what factors could cause an elevated PSA level at my age.
Additionally, does health insurance cover PSA testing or further examinations? Thank you, Doctor.

J, 20~29 year old female. Ask Date: 2021/10/26

Dr. Li Xinyi reply Urology


At your age, issues are generally considered benign, including situations such as sexual activity or cycling that may compress the perineal area, or prostatitis.
It is crucial to undergo further examination and to have regular blood tests for monitoring.

Reply Date: 2021/10/26

More Info


Elevated PSA (Prostate-Specific Antigen) levels can be concerning for many men, especially when they exceed the normal range. In your case, a PSA level of around 7 ng/mL, combined with normal results from a prostate ultrasound and urine tests, suggests that while there may be a reason for concern, it does not definitively indicate prostate cancer.
PSA is a protein produced by both normal and malignant cells of the prostate gland. Elevated levels can be influenced by various factors aside from cancer. For instance, benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate, can lead to increased PSA levels. Prostatitis, which is inflammation of the prostate, can also cause a spike in PSA. Other factors that can influence PSA levels include recent sexual activity, particularly ejaculation, recent prostate exams, or even vigorous exercise, such as cycling, which can put pressure on the prostate.

Given your age of 36, it is relatively uncommon to see significantly elevated PSA levels, and the presence of lower back pain could be indicative of other issues, such as muscular strain or even referred pain from the prostate. It is essential to consider that while elevated PSA can be alarming, many men with high PSA levels do not have prostate cancer.
In terms of next steps, it is advisable to follow up with your healthcare provider. They may recommend a repeat PSA test after a few weeks to see if the levels remain elevated or if they fluctuate. If the PSA remains high, further evaluations may include a digital rectal exam (DRE) and possibly a prostate biopsy, depending on the clinical context and your doctor's assessment.

Regarding insurance coverage for PSA testing and subsequent evaluations, many health insurance plans in the U.S. cover these tests, especially if they are deemed medically necessary. It is best to check with your specific insurance provider to understand what is covered under your plan.

In the meantime, maintaining a healthy lifestyle can be beneficial. This includes a balanced diet rich in fruits, vegetables, and healthy fats, regular exercise, and avoiding known irritants such as alcohol and spicy foods, which may exacerbate prostate issues. Staying hydrated and managing stress levels can also contribute positively to your overall health.

Lastly, it is crucial to have open communication with your healthcare provider about your concerns. They can provide personalized advice based on your medical history and current health status, ensuring that you receive the appropriate care and monitoring for your elevated PSA levels.

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