Muscle Twitches: Possible Neurological Concerns and ALS - Neurology

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Muscle twitching


In May, I noticed that my heels felt numb when I got out of bed, but the sensation disappeared after I walked around for a bit.
This symptom lasted for about one to two weeks.
However, in August, the numbness returned and lasted for another one to two weeks.
In mid-September, I felt a crawling sensation on the top of my foot.
After receiving a vaccine on September 27, I started experiencing an electric shock sensation in the first joint of my left fingers.
At night, my left leg would have slight tremors from the calf to the thigh, and I would also experience sharp pains and twitching in my limbs, back, and head.
On October 5, I visited a doctor who asked me to walk on my heels and toes and also ordered blood tests.
The doctor said everything was fine and prescribed me medication for four days, suggesting that it might be a side effect of the vaccine.
However, even now, my body continues to twitch, usually affecting only one area at a time, and after two to three days, it shifts to another area, mostly on the left side.
Since my mother has amyotrophic lateral sclerosis (ALS), I am concerned that I might be starting to develop symptoms as well.
I would like to ask the doctor if muscle twitching is one of the initial symptoms of ALS.
I have read that weakness is typically the first sign, but I do not currently feel weak.
Thank you, doctor.

Ye, 20~29 year old female. Ask Date: 2021/10/30

Dr. Jiang Junyi reply Neurology


Hello Ms.
Yeh: Amyotrophic lateral sclerosis (ALS) is a term that encompasses a group of motor neuron diseases.
Typically, there are no significant sensory abnormalities, such as the tingling sensations you mentioned.
Motor neurons control muscle movement; generally, the motor neurons in the brain are referred to as upper motor neurons, while those in the brainstem and spinal cord are called lower motor neurons.
When motor neurons become damaged, our muscles do not receive adequate nutrients and chemicals, which can lead to muscle death.
This is a chronic muscle-wasting disease that may cause muscle atrophy.
If upper motor neurons die, abnormal signal transmission may result in muscle fasciculations.
The presence of lower motor neuron signs (muscle atrophy, weakness, and fasciculations) can almost definitively diagnose motor neuron disease, especially when upper motor neuron signs such as enhanced tendon reflexes, the Hoffmann sign, and the Babinski reflex are observed in the same limb.
Clinical diagnosis typically requires electromyography (EMG) and muscle biopsy, among other methods.
I recommend that you consult a neurologist specializing in peripheral nerve disorders for further discussion and examination.
Thank you for your inquiry, and feel free to reach out with any related questions! Wishing you good health and peace.
Dr.
Tao, Neurology, cares about you.

Reply Date: 2021/10/30

More Info


Muscle twitches, medically known as fasciculations, can be concerning, especially when they are accompanied by other symptoms such as numbness, tingling, or weakness. In your case, the sequence of symptoms you've described—starting with tingling sensations in your heels, followed by twitching and electric sensations in your fingers—raises several important considerations regarding potential neurological concerns, including the possibility of conditions like Amyotrophic Lateral Sclerosis (ALS).

Firstly, it's essential to understand that muscle twitches can occur for a variety of reasons, and they are not exclusively indicative of ALS. Common causes include stress, anxiety, fatigue, dehydration, electrolyte imbalances, and even benign fasciculation syndrome. In many cases, these twitches resolve on their own without any underlying serious condition.
The fact that your symptoms began after receiving a vaccine could suggest a temporary reaction, as some individuals experience transient neurological symptoms following vaccinations. However, it's crucial to monitor these symptoms closely, especially since they have persisted beyond the typical duration of a vaccine-related response.

Regarding your concerns about ALS, it's important to note that while muscle twitching can be a symptom of ALS, it is not the only symptom, nor is it necessarily the first. ALS typically presents with a combination of upper and lower motor neuron signs, including muscle weakness, atrophy, and spasticity. Fasciculations may occur, but they are often accompanied by muscle weakness or atrophy in the affected areas. Since you mentioned that you do not currently experience weakness, this is a reassuring sign.
In ALS, muscle twitching is usually a result of denervation of the muscle fibers due to lower motor neuron involvement. This means that if fasciculations are present without accompanying muscle weakness or atrophy, it is less likely to be indicative of ALS. Additionally, the fact that your symptoms have been intermittent and localized to one side of your body may suggest a different underlying issue rather than a progressive neurodegenerative disease.

It is also worth mentioning that the presence of other symptoms, such as the "crawling" sensation on your foot and the electric shock-like feelings in your fingers, could indicate peripheral nerve involvement or other neurological conditions. Conditions such as peripheral neuropathy, multiple sclerosis, or even anxiety-related disorders can manifest with similar symptoms.

Given your family history of ALS, it is understandable that you are concerned about your symptoms. However, it is essential to approach this situation with a comprehensive evaluation. You have already taken a positive step by consulting with a physician, who has performed initial assessments and ruled out some immediate concerns. If your symptoms persist or worsen, it may be beneficial to seek further evaluation from a neurologist who specializes in neuromuscular disorders. They may recommend additional tests, such as electromyography (EMG) or nerve conduction studies, to assess the function of your nerves and muscles more thoroughly.

In summary, while muscle twitching can be a symptom of ALS, it is not definitive on its own, especially in the absence of muscle weakness or atrophy. Your symptoms may be related to a variety of benign causes, and continued monitoring and consultation with healthcare professionals will be crucial in determining the underlying cause and appropriate management. Remember to maintain a healthy lifestyle, manage stress, and stay hydrated, as these factors can also influence muscle function and overall well-being.

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