Medication Withdrawal: Managing Sleep Issues After Discontinuation - Psychiatry

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Hello Doctor, I would like to inquire about medication issues.
I have been experiencing gastric pain due to autonomic nervous system dysfunction, and I have never had insomnia before taking the medication.
After being prescribed Lurasidone for over three months, a pharmacist friend mentioned that this medication can be addictive and suggested I taper off.
I have been reducing the dosage on my own for three weeks and have now stopped for almost three months, but I still have trouble sleeping.
I consulted another doctor who prescribed me Dong Jian (Doxepin) and half a tablet of Mirtazapine.
I fall asleep quickly, but I wake up after 2-3 hours.
I am unsure how long this will continue and whether I will have to deal with this for the rest of my life.
I hope a kind doctor can see my issue and respond to help me.
Thank you.

Zi Zi, 30~39 year old female. Ask Date: 2021/11/07

Dr. Zhang Gengjia reply Psychiatry


Dear Sir/Madam,
From your letter, it is evident that you are experiencing discomfort and distress due to suspected autonomic nervous system dysfunction and physical ailments.
1.
Facing an uncertain future, psychosomatic disorders, such as autonomic nervous system dysfunction, are common in modern society.
This is a chronic condition that requires long-term treatment for recovery.
2.
Psychosomatic disorders (autonomic nervous system dysfunction) are chronic illnesses that have phases of exacerbation, remission, recovery, and relapse.
More than half of patients may experience a recurrence of symptoms even after they have improved.
Due to individual differences in constitution, it may take time to identify the appropriate medication, so please be patient and cooperate with your physician.
3.
In terms of pharmacological treatment, each primary medication requires 4 to 6 weeks to assess its efficacy.
If you experience any discomfort, please note the duration and frequency of the symptoms and discuss them with your physician.
4.
In addition to medication and psychotherapy, repetitive transcranial magnetic stimulation (rTMS) is a non-invasive, anesthesia-free, highly safe treatment that does not require hospitalization.
It can improve anxiety and depressive moods.
For patients with treatment-resistant depression or poor responses to medication, significant improvements in depressive symptoms have been observed following rTMS treatment.
Please discuss the psychosomatic aspects thoroughly with your physician during your follow-up appointment, as some symptoms may be related to the original condition, while others may be side effects of the medication.
Our clinic is open for consultations from Monday to Friday, both in the morning and afternoon.
We recommend that you consider visiting the clinic for a personal assessment of your symptoms, so that together with your physician, you can make the best decision for your health.
Wishing you mental and physical well-being.
Sincerely,
Dr.
Chang Geng-Jia
Department of Psychiatry

Reply Date: 2021/11/07

More Info


Managing sleep issues after discontinuation of medication can be a complex and challenging process, particularly when the medication in question has been used for an extended period. In your case, it seems that you were prescribed a medication (樂穩錠, which is likely a type of benzodiazepine or similar anxiolytic) for symptoms related to autonomic nervous system dysregulation and gastric discomfort. While these medications can be effective for managing anxiety and sleep disturbances, they can also lead to dependence and withdrawal symptoms when discontinued.

When you stop taking a medication like this, especially after prolonged use, your body may experience a rebound effect, where the symptoms that were being managed by the medication return, sometimes more intensely. This can include insomnia, anxiety, and other physical symptoms. The fact that you have been experiencing sleep disturbances for nearly three months after discontinuing the medication is not uncommon. The brain and body need time to readjust to functioning without the medication, which can take weeks or even months.

You mentioned that after switching to a new doctor, you were prescribed 東健 (likely a sedative or anxiolytic) and 美舒鬱 (which may be an antidepressant or mood stabilizer). While these medications can help with sleep onset, waking up after a few hours of sleep is a common issue, especially if your body is still adjusting to the absence of the previous medication. This fragmented sleep can be frustrating and may lead to concerns about whether this pattern will persist indefinitely.

To address your concerns, here are several strategies that may help improve your sleep quality:
1. Sleep Hygiene: Establishing a consistent sleep routine is crucial. Go to bed and wake up at the same time every day, even on weekends. Create a relaxing bedtime ritual, such as reading or taking a warm bath, to signal to your body that it’s time to wind down.

2. Limit Stimulants: Avoid caffeine and nicotine, especially in the afternoon and evening. These substances can interfere with your ability to fall asleep and stay asleep.

3. Create a Comfortable Sleep Environment: Ensure your bedroom is conducive to sleep. This includes a comfortable mattress and pillows, a cool room temperature, and minimal noise and light.

4. Mindfulness and Relaxation Techniques: Practices such as meditation, deep breathing exercises, or gentle yoga can help reduce anxiety and promote relaxation, making it easier to fall asleep and stay asleep.

5. Gradual Medication Adjustment: If you are still experiencing significant sleep disturbances, it may be worth discussing with your doctor the possibility of adjusting your current medications. Sometimes, a gradual tapering off of the previous medication or a different combination of medications can help stabilize sleep patterns.

6. Cognitive Behavioral Therapy for Insomnia (CBT-I): This is a structured program that helps individuals identify and replace thoughts and behaviors that cause or worsen sleep problems. It is often more effective than medication for long-term management of insomnia.

7. Consult a Specialist: If your sleep issues persist, consider consulting a sleep specialist or a psychiatrist who can provide a comprehensive evaluation and tailored treatment plan.

It's important to communicate openly with your healthcare provider about your experiences and concerns. They can help you navigate the complexities of medication management and provide support as you work towards better sleep. Remember, recovery from medication withdrawal and the restoration of healthy sleep patterns can take time, so be patient with yourself during this process.

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