How much longer will it take to return to normal?
I have been experiencing insomnia for three months after discontinuing the medication Lurasidone, which I took for over three months.
This insomnia is not caused by autonomic nervous system dysfunction; my symptoms related to autonomic dysregulation were limited to stomach pain, nausea, and vomiting.
Interestingly, after stopping Lurasidone, my stomach pain symptoms have significantly decreased.
Before taking Lurasidone, I never had insomnia.
The doctor who initially prescribed Lurasidone told me that taking it for life would not cause any issues.
However, my current doctor is unsure why my previous doctor recommended long-term use of Lurasidone.
He mentioned that there are many alternative medications available.
I am concerned about how long the insomnia after discontinuation will last.
I tapered off the medication over three weeks before stopping completely, and I wonder if that was too fast.
Currently, I am taking Trazodone and Mirtazapine, but I can only sleep for 2 to 3 hours before waking up.
Although I can lie down and fall back asleep, I feel increasingly fatigued, and I have low energy during the day.
The doctor I am seeing now believes that my condition will gradually improve, so he prescribed a lighter medication, but I am uncertain how long it will take to return to my previous state.
I have read online that discontinuation can lead to poor sleep in the latter half of the night, and it may persist for months or even years.
Seeing this information makes me anxious about how much longer I can endure this or if I should return to taking Lurasidone.
I hope the doctor can provide some answers, and I would be very grateful.
Xiao Hao, 30~39 year old female. Ask Date: 2021/11/22
Dr. Wu Enliang reply Psychiatry
Hello, internet user: It is recommended to incorporate sleep hygiene practices as follows (https://www1.cgmh.org.tw/intr/intr2/c3360/E_Sleep(Huang1).htm), and to avoid using the internet or mobile phones one hour before bedtime, which can facilitate the gradual discontinuation of sedative-hypnotic medications.
In terms of non-pharmacological treatments, establishing good sleep hygiene is essential, such as: 1.
Maintaining a regular sleep schedule by going to bed and waking up at the same time each day.
2.
Do not force yourself to sleep; if you lie in bed for more than thirty minutes without falling asleep, get up and engage in a calming activity until you feel sleepy again.
3.
Strictly limit the time spent in bed; do not even sit on the bed during the day, only go to bed when you are ready to sleep at night.
4.
Maintain a comfortable sleep environment: appropriate room temperature, lighting, minimal noise, and a comfortable mattress.
5.
Avoid using the bed or bedroom for other activities such as watching TV, talking on the phone, or discussing matters.
6.
Avoid caffeine, tea, cola, alcohol, and smoking after dinner.
7.
To prevent nocturia that disrupts sleep, it is best to limit fluid intake after dinner.
8.
A light snack before bed can aid sleep, but avoid overeating.
9.
Engage in regular exercise daily, and perform gentle and relaxing activities before bed, such as taking a warm bath, muscle relaxation, and breathing exercises; avoid vigorous activities before sleep.
10.
Maintain a regular and active lifestyle, and actively participate in social activities.
Additionally, muscle relaxation training or self-hypnosis training (which can be consulted with a psychiatrist or psychologist) can also help improve sleep quality and insomnia issues.
Dr.
Wu Enliang
Reply Date: 2021/11/22
More Info
Recovering from medication-induced insomnia, particularly after discontinuing benzodiazepines like Lorazepam, can be a complex and individualized process. The timeline for recovery varies significantly from person to person, influenced by factors such as the duration of medication use, the dosage, individual physiology, and underlying mental health conditions.
When you stop taking a medication like Lorazepam after a prolonged period of use, your body may experience withdrawal symptoms, including insomnia. This is because benzodiazepines work by enhancing the effect of a neurotransmitter called gamma-aminobutyric acid (GABA), which has a calming effect on the brain. Over time, your body can become reliant on the medication to maintain this balance, and when you stop taking it, your brain may struggle to adjust, leading to symptoms like anxiety and insomnia.
In general, acute withdrawal symptoms from benzodiazepines can last anywhere from a few days to a couple of weeks. However, the insomnia you're experiencing may persist longer, especially if there are underlying issues such as anxiety or depression that were being managed by the medication. Some studies suggest that post-withdrawal insomnia can last for several months, and in some cases, it may take a year or more for normal sleep patterns to return.
Your experience of waking up after only 2-3 hours of sleep and feeling increasingly fatigued is not uncommon among individuals who have recently stopped taking benzodiazepines. This can be exacerbated by anxiety or stress, which can further disrupt sleep. It's important to note that while some people may recover quickly, others may find that their sleep disturbances linger, particularly if they have a history of anxiety or other mood disorders.
To aid in your recovery, consider the following strategies:
1. Sleep Hygiene: Establish a consistent sleep schedule by going to bed and waking up at the same time every day. Create a relaxing bedtime routine and make your sleep environment as comfortable as possible—dark, quiet, and cool.
2. Cognitive Behavioral Therapy for Insomnia (CBT-I): This is a structured program that helps you identify and replace thoughts and behaviors that cause or worsen sleep problems. It has been shown to be effective for treating insomnia.
3. Gradual Medication Adjustment: If you are currently taking medications like Quetiapine or Trazodone, discuss with your doctor the possibility of adjusting the dosage or trying different medications that may have a lower risk of dependence.
4. Mindfulness and Relaxation Techniques: Practices such as meditation, deep breathing exercises, and progressive muscle relaxation can help reduce anxiety and promote better sleep.
5. Consultation with a Specialist: If your insomnia persists, consider consulting a sleep specialist or a psychiatrist who can provide tailored advice and treatment options.
6. Patience and Support: Recovery from medication-induced insomnia can take time. It’s crucial to be patient with yourself and seek support from healthcare professionals, friends, or support groups.
In conclusion, while it’s difficult to predict an exact timeline for recovery from medication-induced insomnia, many individuals find that with appropriate strategies and support, their sleep improves over time. If you feel overwhelmed or unsure about your current treatment plan, don’t hesitate to reach out to your healthcare provider for further guidance. They can help you navigate this challenging period and find the most effective approach for your situation.
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