Medication Side Effects in OCD and Depression Treatment - Psychiatry

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Drug side effects


Hello Dr.
Wu,
I apologize for the lengthy message.
Here’s my situation: I have obsessive-compulsive disorder (OCD) and have been taking Sertraline (Zoloft) for about a month.
Recently, I am preparing for an exam.
Before taking the medication, I felt more motivated; for example, I would study while eating, and I felt anxious and guilty if I wasted any time.
However, after starting the medication, I often don’t want to get out of bed and sleep until noon.
I frequently skip my review classes and feel that studying is not important and I don’t want to do anything.
Additionally, when I study, I have a sense of not accomplishing anything.
I want to ask whether this is due to a lack of willpower or the effects of the medication.
Am I actually not sick, and is it the medication that is making me feel strange? Or is it that my original personality was somewhat lax, and I relied on anxiety to maintain my study habits, but now that I’m on medication, I’ve reverted to being more relaxed? Or could this be a side effect of the medication?
I often think about stopping the medication but am hesitant because I feel that it is my only salvation in returning to normalcy.
During my follow-up appointment, it seemed that the only medication with fewer side effects is Sertraline, so I might not be able to switch medications.
Should I reduce the dosage instead?
I appreciate your advice and thank you for your help!

A, 10~19 year old female. Ask Date: 2021/11/29

Dr. Wu Enliang reply Psychiatry


Hello, online friend: There could be various reasons for this.
Studying for exams can indeed be boring and tedious.
If you're concerned about potential side effects from the medication, you might consider taking half a dose.
However, I still recommend discussing this with your physician during your next appointment.
Dr.
Wu Enliang

Reply Date: 2021/11/29

More Info


Understanding medication side effects in the treatment of Obsessive-Compulsive Disorder (OCD) and depression is crucial, especially when patients experience changes in their motivation and daily functioning after starting medication. Your concerns about feeling less motivated and more lethargic after beginning treatment are valid and warrant a thoughtful discussion.

Firstly, it’s important to recognize that medications used to treat OCD and depression, such as selective serotonin reuptake inhibitors (SSRIs) like Fluoxetine or Sertraline, can have varying effects on individuals. While these medications are effective for many, they can also lead to side effects that may impact daily life. Common side effects include fatigue, sleep disturbances, and changes in motivation or interest in activities. These side effects can sometimes be mistaken for the underlying condition itself, making it challenging to determine whether the medication is helping or hindering your progress.

In your case, the feelings of lethargy and disinterest in studying could indeed be related to the medication. It’s not uncommon for patients to experience a sense of emotional blunting or a decrease in motivation when starting SSRIs. This can be particularly concerning when you are preparing for exams, as it may feel counterproductive to your goals. However, it’s also possible that your previous anxiety and compulsive behaviors were driving you to maintain a high level of productivity, and the medication is allowing you to feel more relaxed, which might be perceived as a lack of motivation.

It’s crucial to differentiate between the effects of the medication and your natural tendencies. Some individuals may find that their anxiety was previously propelling them to work harder, and once that anxiety is alleviated, they may feel less compelled to engage in the same level of activity. This doesn’t necessarily mean that you lack willpower or that you are not “sick” enough to need medication; rather, it may indicate a shift in how you respond to stress and tasks.

If you are considering stopping the medication, it’s essential to consult with your prescribing physician first. Abruptly discontinuing medication can lead to withdrawal symptoms and a potential relapse of your OCD or depression. Your doctor can help you assess whether your current dosage is appropriate or if adjustments are necessary. Sometimes, a lower dose or a different medication may alleviate side effects while still providing therapeutic benefits.

Additionally, it’s worth exploring complementary strategies alongside medication. Engaging in regular physical activity, practicing mindfulness, or participating in cognitive-behavioral therapy (CBT) can enhance your treatment outcomes. Exercise, in particular, has been shown to have mood-lifting effects and can help mitigate some side effects of medications.

Lastly, it’s important to maintain open communication with your healthcare provider about your experiences. They can provide guidance tailored to your specific situation and help you navigate the complexities of medication management. Remember, finding the right balance in treatment can take time, and it’s okay to seek support during this process.

In summary, while medication can be a vital part of managing OCD and depression, it’s essential to monitor its effects closely and communicate any concerns with your healthcare provider. Understanding the interplay between your medication, your mental health, and your daily functioning is key to finding a treatment plan that works for you.

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