Affective Psychosis: Differences, Recovery, and Hallucinations - Psychiatry

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Affective Psychosis


Hello, doctor.
I would like to ask:
1.
Is there a difference between schizoaffective disorder and mood disorder with psychotic features? My prescription states "major depressive disorder in remission, schizoaffective disorder," but when I asked my doctor about my diagnosis, he said it is mood disorder with psychotic features.
2.
Does mood disorder with psychotic features count as a type of psychosis? The doctor mentioned that there is a difference between the two, but I am unsure what that difference is.
My main symptoms are depression and auditory hallucinations.
I previously experienced paranoid delusions, but those have improved (I think), while the other symptoms persist.
3.
Can mood disorder with psychotic features be cured? I have heard that psychosis is often irreversible, and I am unsure if mood disorder with psychotic features is the same.
4.
Is it possible for auditory hallucinations to never go away? I have been in treatment for five years, and the hallucinations started appearing daily from the third year, often with suicidal content.
I am very afraid that I will have to live with this for the rest of my life.
I have tried various antipsychotic medications, except clozapine, but when I took aripiprazole, I experienced binge eating as a side effect and gained nearly 20 kilograms in six months.
Therefore, my doctor is hesitant to prescribe clozapine.
Is there a chance that my auditory hallucinations could resolve on their own? Thank you for your help!

Evonne, 20~29 year old female. Ask Date: 2021/12/09

Dr. Lin Mianzhang reply Psychiatry


Hello Evonne:
1.
Schizoaffective disorder and affective psychosis are merely differences in translation; they refer to the same condition, which is known in English as schizoaffective disorder.
"Schizo-" refers to splitting, while "affective" pertains to emotions.

2.
Schizoaffective disorder is a type of schizophrenia, with the distinction that it presents more pronounced emotional (mood) symptoms, which may include depression or bipolar symptoms.
In your case, it seems to primarily involve depressive symptoms.

3.
The course of schizoaffective disorder is similar to that of schizophrenia; it is a chronic condition that can be managed with medication, but it cannot be completely cured.

4.
Approximately one-third of patients with schizophrenia continue to experience residual symptoms even after treatment, so auditory hallucinations may not completely disappear.
However, as one ages, the symptoms of auditory hallucinations may gradually diminish, and the amount of medication needed in the future may also decrease.
If you have not yet tried clozapine and if the auditory hallucinations are significantly distressing to you, it would be advisable to discuss with your physician the possibility of trying clozapine, as there is clear evidence showing its efficacy is superior to that of other medications.
Some patients have experienced a complete resolution of their auditory hallucinations after using this medication.
Wishing you a speedy recovery!

Reply Date: 2021/12/09

More Info


Understanding affective psychosis, particularly the distinctions between schizoaffective disorder and affective psychosis, is crucial for effective treatment and recovery. Let's break down your questions systematically.

1. Differences Between Schizoaffective Disorder and Affective Psychosis: Schizoaffective disorder is characterized by a combination of symptoms of schizophrenia (such as hallucinations or delusions) and mood disorder symptoms (like depression or mania). In contrast, affective psychosis primarily refers to psychotic symptoms that occur in the context of a mood disorder. Your diagnosis of "severe depression in remission, schizoaffective disorder" suggests that while you may have experienced severe depressive episodes, you also exhibit psychotic symptoms that are not solely tied to mood episodes. The distinction lies in the presence of psychotic symptoms independent of mood episodes in schizoaffective disorder, whereas in affective psychosis, the psychotic symptoms are directly related to mood disturbances.

2. Is Affective Psychosis Considered a Form of Psychosis?: Yes, affective psychosis is indeed considered a form of psychosis. It involves the presence of hallucinations or delusions that are directly related to mood disorders. Your experience of depression coupled with hallucinations aligns with this classification. The key difference is that in schizoaffective disorder, psychotic symptoms can persist even when mood symptoms are not present.

3. Can Affective Psychosis Be Cured?: Recovery from affective psychosis varies from person to person. While some individuals may experience significant improvement and even remission of symptoms, others may continue to face challenges. The notion that schizophrenia is irreversible is somewhat misleading; many individuals with schizoaffective disorder can lead fulfilling lives with appropriate treatment, which often includes a combination of medication, therapy, and support systems. Continuous monitoring and adjustments in treatment are essential, as what works for one individual may not work for another.

4. Possibility of Hallucinations Persisting: Hallucinations, particularly auditory ones, can be persistent and may not completely disappear for everyone. However, they can often be managed effectively with the right treatment. It’s important to communicate openly with your healthcare provider about the nature of your hallucinations, especially if they are urging self-harm. Adjustments in medication or the introduction of new therapeutic approaches, such as cognitive behavioral therapy (CBT), can help manage these symptoms.
Regarding your experience with weight gain from certain medications, this is a common side effect of many antipsychotics. Discussing alternative medications with your doctor, including those that may have a lower risk of weight gain, is crucial. Medications like aripiprazole or lurasidone may be options worth exploring, but this should be done under the guidance of your healthcare provider.

In conclusion, while the journey through affective psychosis can be challenging, many individuals find relief and manage their symptoms effectively with the right treatment plan. Continuous communication with your healthcare provider, exploring various treatment options, and engaging in supportive therapies can significantly enhance your quality of life. Remember, recovery is a process, and it’s essential to remain hopeful and proactive in your treatment.

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