Can I Use Both Salicylic Acid and Azelaic Acid for Acne? - Dermatology

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Regarding acne and pimples?


Hello, doctor.
I have some questions regarding my skincare routine.
I have been using azelaic acid on my face, and I've noticed that my acne scars are fading quite quickly.
However, it hasn't been effective for my blackheads, and sometimes I even see my blackheads worsening into pimples.
Therefore, I am considering using a salicylic acid product to treat the blackheads while continuing to use azelaic acid for the acne scars.
Is this okay? Will using both types of acids be harsh on my skin? I appreciate your guidance on this matter.
Thank you for your time, and I apologize for the interruption! QAQ

Martin, 20~29 year old female. Ask Date: 2021/12/17

Dr. Wu Yuxin reply Dermatology


It can be used, but not at the same time.

Reply Date: 2021/12/17

More Info


Using both salicylic acid and azelaic acid for acne treatment can be effective, but it requires careful consideration of your skin type and the specific concerns you are addressing. Both of these acids have unique properties and mechanisms of action that can complement each other when used correctly.

Salicylic Acid is a beta hydroxy acid (BHA) that is particularly effective for treating acne due to its ability to penetrate the pores and exfoliate the inside of the follicle. It helps to dissolve the debris that clogs pores, reducing the formation of comedones (blackheads and whiteheads) and preventing future breakouts. Salicylic acid also has anti-inflammatory properties, which can help reduce the redness and swelling associated with active acne lesions.

Azelaic Acid, on the other hand, is a dicarboxylic acid that has both antibacterial and anti-inflammatory properties. It works by inhibiting the growth of acne-causing bacteria (Propionibacterium acnes) and reducing keratin production, which can help prevent clogged pores. Azelaic acid is also known for its ability to improve skin texture and reduce hyperpigmentation, making it beneficial for treating post-acne scars and dark spots.

When considering the simultaneous use of these two acids, it is important to keep the following points in mind:
1. Skin Sensitivity: Both salicylic acid and azelaic acid can cause irritation, especially when first introduced to your skincare routine. If you have sensitive skin, it may be wise to start with one product and gradually introduce the other to monitor how your skin reacts.

2. Application Timing: To minimize irritation, you might consider using these products at different times of the day. For example, you could apply salicylic acid in the morning and azelaic acid in the evening. This approach allows your skin to benefit from both ingredients without overwhelming it.

3. Layering: If you choose to use both products in the same routine, apply the lighter product first. Typically, salicylic acid is more fluid and can be applied before azelaic acid. However, ensure that your skin has fully absorbed the first product before applying the second to reduce the risk of irritation.

4. Moisturization: Both acids can be drying, so incorporating a good moisturizer into your routine is essential. Look for non-comedogenic moisturizers that won't clog your pores while providing hydration.

5. Consultation with a Dermatologist: Since you are already seeing results with azelaic acid for your acne scars but are experiencing issues with comedones, it would be beneficial to discuss your plan with a dermatologist. They can provide personalized advice based on your skin type and the severity of your acne.

In conclusion, using both salicylic acid and azelaic acid can be a strategic approach to managing acne and post-acne marks. However, it is crucial to pay attention to your skin's response and adjust your routine accordingly. If irritation occurs, consider reducing the frequency of application or consulting a dermatologist for tailored recommendations.

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