Eye Pressure: Steroid Use and Its Effects on Ocular Health - Ophthalmology

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Consultation on intraocular pressure and eye medications?


One year ago, the intraocular pressure in both eyes was 18.
Six months ago and recently, the left eye measured 22 and the right eye 15.
I have a history of nasal allergies and conjunctivitis, and I have been using Avamys nasal spray and Winston Good Vision 5ml, 0.1% eye drops for nearly two years.
Both retinal and fundus examinations were normal, with visual acuity at 1.0.
I have not yet had a visual field test, but I have not experienced any blurriness.
I would like to ask the doctor: 1.
Is the elevated intraocular pressure due to long-term steroid use? 2.
Is it possible for the intraocular pressure to return to normal after discontinuing the medication? If so, how long might that take? 3.
Assuming the intraocular pressure does return to normal, will I be prohibited from using steroid medications (eye drops, ointments, nasal sprays, oral medications) for life? Or is it possible to use them short-term but not long-term?

Xiang, 40~49 year old female. Ask Date: 2022/01/05

Dr. He Jianxian reply Ophthalmology


Long-term use of corticosteroids can indeed lead to increased intraocular pressure.
It is advisable to monitor the intraocular pressure after discontinuation for 2-4 weeks to see if it returns to normal.
If it does not, consideration should be given to using antihypertensive medications for a period of time and checking the visual field.
Once the intraocular pressure is reduced to normal levels, short-term use of corticosteroids should still be acceptable.
However, if your intraocular pressure remains stable and you require long-term allergy treatment, you might consider using non-steroidal eye drops, as they are less likely to cause side effects.
Dr.
He Jianxian, Ophthalmology Department, Nantou Hospital.

Reply Date: 2022/01/05

More Info


Understanding eye pressure and its relationship with steroid use is crucial for maintaining ocular health. Your situation, involving the use of nasal sprays and eye drops containing steroids, raises important questions about the potential effects on intraocular pressure (IOP) and overall eye health.

1. Is Eye Pressure Elevated Due to Long-Term Steroid Use?
Long-term use of corticosteroids, whether systemic or topical, can lead to an increase in intraocular pressure. This is particularly true for certain individuals who may be more sensitive to the effects of steroids. The mechanism behind this involves the alteration of aqueous humor dynamics. Corticosteroids can increase the resistance to outflow of aqueous humor through the trabecular meshwork, leading to elevated IOP. In your case, the increase in IOP from 18 mmHg to 22 mmHg in your left eye could indeed be attributed to the prolonged use of steroid medications, especially if you have been using them consistently over the past two years.

2. Can Eye Pressure Return to Normal After Discontinuing Steroids?
Upon discontinuation of steroid use, it is possible for intraocular pressure to return to baseline levels, but this can vary significantly among individuals. The timeline for recovery can also differ; some may see improvements within days, while others may take weeks or even months for their IOP to stabilize. It is essential to have regular follow-ups with your eye care provider to monitor your IOP after stopping the medication. They may recommend a gradual tapering of the steroid to minimize potential rebound effects.

3. Can You Use Steroids Again After Eye Pressure Normalizes?
If your IOP returns to normal after stopping steroid use, it does not necessarily mean you must avoid all corticosteroids for life. However, caution is advised. Short-term use of steroids may be acceptable, especially in cases of acute inflammation or allergic reactions, but long-term use should be avoided if you have a history of steroid-induced ocular hypertension. It is crucial to discuss any future use of steroids with your healthcare provider, who can evaluate the risks and benefits based on your specific situation. They may suggest alternative treatments that have a lower risk of elevating IOP.

In summary, while steroids can be effective for managing conditions like allergic rhinitis and conjunctivitis, their potential impact on eye pressure should not be overlooked. Regular monitoring of IOP, especially when using steroids, is essential for preventing complications such as glaucoma. If you experience any symptoms like blurred vision or eye discomfort, it is vital to seek medical attention promptly. Always consult with your eye care professional before making any changes to your medication regimen, as they can provide personalized guidance based on your ocular health and history.

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