When to Use Eye Drops for Morning Eye Discomfort - Ophthalmology

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Inquiry about eye drops?


Hello Doctor, for the past two weeks, I have been experiencing a prickly and dry sensation in my left eye upon waking up.
There are also more blood vessels visible at the corners of my eyes, but the symptoms improve after about 30 minutes of being awake.
I also notice an increase in discharge upon waking.
After seeing a doctor, I was told there is mild inflammation, and I was prescribed Antazoline/tetrahydrozoline eye drops to use as needed.
I would like to know if I should use the drops when I experience these symptoms in the morning, as sometimes they improve on their own and I don't feel much discomfort, so I hesitate to use them.
How should I determine when to use the drops? I read the instructions on the medication packaging, and the doctor mentioned that the increased blood vessels could warrant using the drops, but I find it a bit contradictory that one of the side effects is conjunctival hyperemia.
Additionally, in Hsinchu, the wind can be strong, and I sometimes feel dryness and see more blood vessels in my eyes.
Is it appropriate to use these eye drops in this situation? Thank you for your guidance!

Xiao Chen, 20~29 year old female. Ask Date: 2022/01/11

Dr. Gao Pilin reply Ophthalmology


Hello, Xiao Chen: Tetrahydrozoline has vasoconstrictive properties, which can alleviate vascular congestion.
However, a side effect is that prolonged use can lead to dependence, making congestion more likely when the medication is not used.
It can be used for the symptoms you described, but if the symptoms improve, you should discontinue the medication.
It can also be used for dry eyes and excessive redness.

Reply Date: 2022/01/11

More Info


When it comes to morning eye discomfort, particularly symptoms like dryness, redness, and irritation, it’s essential to understand the underlying causes and appropriate management strategies. Based on your description, it seems you are experiencing a combination of dry eyes and mild inflammation, which can be exacerbated by environmental factors such as wind or prolonged screen time.

Understanding Your Symptoms
1. Dryness and Irritation: Upon waking, your eyes may feel dry and irritated due to a lack of moisture during sleep. This is common, especially for individuals with pre-existing conditions like dry eye syndrome. During sleep, tear production decreases, leading to dryness upon waking.

2. Redness: The presence of blood vessels in the eyes (conjunctival injection) can occur due to irritation or inflammation. This can be aggravated by environmental factors, such as wind or allergens, which may cause your eyes to become more reactive.

3. Discharge: Increased secretion of mucus or discharge upon waking can indicate a mild inflammatory response. This is often a protective mechanism, but it can also be a sign of underlying issues that may need attention.


When to Use Eye Drops
Given that your doctor prescribed Antazoline/tetrahydrozoline, which is an antihistamine combined with a decongestant, it’s important to use it judiciously. Here are some guidelines for when to use the eye drops:
- Immediate Use: If you wake up with significant discomfort, redness, or irritation that affects your ability to see clearly or perform daily activities, it is appropriate to use the eye drops. These drops can help alleviate symptoms quickly.

- Mild Symptoms: If your symptoms are mild and improve within 30 minutes, you may choose to wait before using the drops. Monitor how your eyes feel after waking; if they improve significantly, you might not need to use the drops.

- Environmental Factors: If you are in a windy environment or exposed to allergens, using the drops preemptively can help prevent discomfort.

Understanding Side Effects
You mentioned concerns about potential side effects, such as conjunctival hyperemia (redness). While the drops can relieve redness, they may also cause rebound redness if used excessively. This means that over time, your eyes may become more reliant on the drops, leading to increased redness when not used. Therefore, it’s crucial to follow your doctor’s advice on frequency and duration of use.


Additional Recommendations
1. Artificial Tears: Consider using preservative-free artificial tears in addition to your prescribed drops. These can provide moisture and relief without the risk of rebound redness. They can be used more frequently and are safe for daily use.

2. Environmental Modifications: If you find that wind exacerbates your symptoms, consider wearing wrap-around sunglasses when outdoors to protect your eyes from environmental irritants.

3. Regular Check-ups: Since you have a history of eye discomfort, regular follow-ups with your eye care provider are essential. They can monitor your condition and adjust your treatment plan as necessary.

4. Lifestyle Adjustments: Ensure you take regular breaks from screens, maintain proper hydration, and consider using a humidifier in dry environments to help alleviate symptoms.

In conclusion, using the prescribed eye drops when experiencing significant discomfort is appropriate, but be mindful of their potential side effects. Regular communication with your eye care provider will help you manage your symptoms effectively and maintain optimal eye health.

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