Concerns About Amoxicillin Use Before Dental Implant Surgery - Dentistry

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Amoxicillin medication issues?


Hello Dr.
Lin, I would like to ask about my situation.
I have scheduled a debridement surgery for peri-implantitis on January 23.
During the waiting period, I took 10 capsules of antibiotics from January 10 to January 13 (the clinic provided the medication, but I stopped taking 2 capsules due to esophageal ulcers).
On January 17, when I visited the dentist, he prescribed another three days' worth (a total of 12 capsules), which I took from January 19 to January 22.
My question is, with the way I spaced out the Amoxicillin and having stopped 2 capsules the first time, will this lead to antibiotic resistance? Thank you! Additionally, could taking so many antibiotics have any negative effects?

Kiki, 30~39 year old female. Ask Date: 2022/01/20

Dr. Lin Jiayong reply Dentistry


Hello, since there was more than a week between the first and second doses, there should not be a significant correlation between the two.
If you are concerned about the frequent use of the same antibiotic, you can inform your physician and request an alternative broad-spectrum antibiotic.
Additionally, please remember that the use of antibiotics serves specific purposes, including treating diseases and preventing infections.
It is advisable to consult with the prescribing physician and pharmacist for clarity.

Reply Date: 2022/01/20

More Info


Amoxicillin is a commonly prescribed antibiotic that belongs to the penicillin group. It is widely used to treat various bacterial infections, including those related to dental procedures. However, concerns about antibiotic resistance and potential side effects are valid, especially when antibiotics are used frequently or inappropriately.

In your case, you mentioned taking a total of 22 capsules of Amoxicillin over a short period, with a break in between due to an esophageal ulcer. The concern about developing antibiotic resistance is indeed important. Antibiotic resistance occurs when bacteria evolve and become less susceptible to the effects of an antibiotic. This can happen when antibiotics are overused or misused, leading to a situation where the bacteria that survive are those that have developed resistance.

The interval between your first and second course of Amoxicillin is crucial. Since you had a break of over a week between the two courses, it is less likely that this will contribute significantly to antibiotic resistance. However, the cumulative exposure to the antibiotic in a short timeframe does raise concerns. It is essential to use antibiotics only when necessary and as prescribed by a healthcare professional. If you have concerns about the frequency of your Amoxicillin use, it would be prudent to discuss this with your dentist or physician, who may consider alternative antibiotics or treatment strategies.

Regarding potential side effects, Amoxicillin is generally well-tolerated, but it can cause side effects such as gastrointestinal disturbances (nausea, diarrhea), allergic reactions, and, in rare cases, more severe reactions like anaphylaxis. Long-term or excessive use of antibiotics can also disrupt the normal flora of the gut, leading to conditions such as Clostridium difficile infection, which can cause severe diarrhea and colitis.

In your situation, it is also important to consider the context of your dental surgery. Antibiotics are often prescribed prophylactically to prevent infections, especially in patients with a history of infections or other medical conditions. However, the decision to use antibiotics should be based on a thorough assessment of the risks and benefits. If you have a history of chronic infections or other complications, your dentist may have deemed it necessary to prescribe antibiotics to minimize the risk of postoperative infections.

In summary, while your use of Amoxicillin raises valid concerns about antibiotic resistance and potential side effects, the specific circumstances of your treatment and the intervals between doses are critical factors. It is always best to have an open dialogue with your healthcare provider about any concerns you have regarding your treatment plan. They can provide personalized advice based on your medical history and the specifics of your upcoming dental procedure. If you feel uncertain about the prescribed antibiotic, do not hesitate to seek a second opinion or ask for alternatives that may be more suitable for your situation.

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