Post-Cryotherapy Pigmentation Issues After Viral Wart Treatment - Dermatology

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Post-treatment pigmentation after cryotherapy for viral warts?


Hello Doctor: I recently had viral warts on my face, and the doctor performed cryotherapy on me about seven times.
However, I now have a large area of significant hyperpigmentation on my face.
The doctor later prescribed tranexamic acid for me to take and also recommended applying azelaic acid, but after two months, the pigmentation has not faded at all.
The dark area on my face looks really unattractive and very noticeable.
Will this pigmentation eventually fade? Are there suitable laser treatments for this? I'm really worried that my face will look like this for the rest of my life.

Fei Fei, 20~29 year old female. Ask Date: 2022/01/25

Dr. Li Yufen reply Dermatology


Hello: Generally, post-inflammatory hyperpigmentation will gradually fade.
In addition to taking oral tranexamic acid, you can also supplement with vitamin C and ensure proper sun protection, reapplying every 2-3 hours.
If there is a poor reaction to azelaic acid, you may consider switching to tretinoin ointment or a triple-combination whitening cream.
If considering out-of-pocket laser treatments, you might look into broadband light (BBL) laser or picosecond laser.
If the skin condition does not improve, it is advisable to consult a dermatologist for diagnosis and treatment.
Thank you!

Reply Date: 2022/01/25

More Info


Post-cryotherapy pigmentation issues, especially following the treatment of viral warts, can be a common concern among patients. Cryotherapy, which involves freezing the wart tissue, can sometimes lead to post-inflammatory hyperpigmentation (PIH), particularly in individuals with darker skin types. This condition occurs when the skin responds to injury or inflammation by producing excess melanin, leading to dark patches.

In your case, after undergoing seven sessions of cryotherapy, it is understandable that you are worried about the persistent pigmentation on your face. The use of tranexamic acid and azelaic acid is a common approach to help manage hyperpigmentation. Tranexamic acid works by inhibiting melanin synthesis and can be effective in reducing pigmentation over time. Azelaic acid, on the other hand, has anti-inflammatory properties and can help in treating both acne and hyperpigmentation.

It is important to note that pigmentation issues can take time to resolve. In many cases, it may take several months for the skin to return to its normal tone, especially after a significant treatment like cryotherapy. Factors such as skin type, the depth of the pigmentation, and individual healing responses can all influence recovery time.
If after two months of treatment you have not seen any improvement, it may be worth discussing alternative options with your dermatologist. Laser treatments, such as fractional laser therapy or intense pulsed light (IPL), can be effective in treating stubborn pigmentation. These treatments work by targeting the melanin in the skin and can help to break up the pigment, leading to a more even skin tone. However, it is crucial to consult with a qualified dermatologist who can assess your specific situation and recommend the most appropriate treatment.

In addition to medical treatments, there are several self-care measures you can adopt to help manage pigmentation:
1. Sun Protection: Protecting your skin from sun exposure is crucial. Use a broad-spectrum sunscreen with an SPF of 30 or higher daily, even on cloudy days. Sun exposure can exacerbate pigmentation issues, so wearing protective clothing and seeking shade when outdoors is also advisable.

2. Gentle Skincare: Use gentle, non-irritating skincare products. Avoid harsh scrubs or exfoliants that can further irritate the skin and worsen pigmentation.

3. Hydration: Keeping your skin well-hydrated can support the healing process. Look for moisturizers that contain ingredients like hyaluronic acid, which can help retain moisture in the skin.

4. Patience: Understand that skin healing is a gradual process. While it can be frustrating to see persistent pigmentation, many cases improve over time with consistent care.

5. Follow-Up: Regular follow-up appointments with your dermatologist are essential. They can monitor your progress and adjust your treatment plan as needed.

In summary, while post-cryotherapy pigmentation can be distressing, it is often treatable. With the right combination of topical treatments, sun protection, and possibly laser therapy, there is a good chance that the pigmentation will improve over time. Always consult with your dermatologist to tailor a treatment plan that best suits your skin's needs.

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