Post-Treatment Skin Changes After Viral Warts - Dermatology

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After the treatment of viral warts, there may be a hard lump in the surrounding skin?


Hello Doctor: A few months ago, I had a small pimple on the back of my hand that was persistent and somewhat inflamed.
I eventually went to a dermatologist who diagnosed it as a viral infection, and I underwent cryotherapy.
During my follow-up visits, both doctors said it has been completely cleared.
I have a history of eczema and occasionally return for check-ups.
However, before the treatment, I noticed a small hard area in the surrounding normal skin, which remains even after treatment.
The doctor mentioned that it might be due to subcutaneous tissue proliferation caused by the infection, or it could be a ganglion cyst.
I then consulted a rehabilitation specialist and had an ultrasound, which indicated that it is likely subcutaneous tissue proliferation.
I mainly want to ask if there could still be a virus inside that might turn into a viral wart, or if the absence of changes in the skin means I should just leave it alone and it will eventually resolve on its own.
I am very concerned about coming into contact with others or other parts of my own body.
(I recently received the HPV nine-valent vaccine, thinking that these issues would be out of my life, but unfortunately, I still contracted it after the second dose.) Thank you, Doctor, for taking the time to respond.

Nìmíng, 30~39 year old female. Ask Date: 2024/06/29

Dr. Wu Yuxin reply Dermatology


After cryotherapy for viral warts, it is necessary to observe for at least six months to confirm whether complete eradication has been achieved.

Reply Date: 2024/06/29

More Info


Understanding post-treatment skin changes after viral warts can be quite complex, especially when considering the various factors that contribute to skin healing and the potential for recurrence of viral infections. In your case, it sounds like you have undergone treatment for a viral wart on your hand, and while the wart itself has been treated, you are now noticing some changes in the surrounding skin that are causing concern.

Firstly, it's important to understand that after treatment for viral warts, particularly with methods like cryotherapy (freezing), the skin can undergo several changes as it heals. The initial response to treatment often includes inflammation, which can manifest as redness, swelling, and sometimes a hardened area of skin. This is a normal part of the healing process as the body works to repair the affected tissue and eliminate the viral infection.

The hard area you are feeling next to the treated wart could indeed be a result of the body's response to the viral infection. In some cases, the skin may develop fibrous tissue or scar tissue as it heals, which can feel different from the surrounding normal skin. This is not uncommon and does not necessarily indicate that the virus is still present or that it will lead to the formation of new warts.
Regarding your concern about the possibility of the virus remaining in the skin, it's important to note that while the human papillomavirus (HPV), which causes warts, can remain dormant in the body, the likelihood of it reactivating and causing new warts in the same area is relatively low if the initial wart has been successfully treated. The immune system typically develops a response to the virus, which helps prevent future outbreaks. However, if there are changes in your immune status or if you are exposed to the virus again, there is always a possibility of new warts developing.

You mentioned that you have a history of eczema (湿疹), which can complicate the healing process. Eczema can lead to skin barrier dysfunction, making the skin more susceptible to infections and irritation. It's crucial to manage your eczema effectively, as uncontrolled eczema can lead to secondary infections or exacerbate existing skin conditions.

In terms of management, if the area remains unchanged and does not exhibit signs of infection (such as increased redness, warmth, swelling, or pus), it may be reasonable to monitor it over time. Many skin changes will resolve on their own as the body continues to heal. However, if you notice any new symptoms or if the area becomes painful or bothersome, it would be wise to consult with your dermatologist or healthcare provider for further evaluation.

Lastly, your concerns about spreading the virus to others are understandable, especially after receiving the HPV vaccine. While the vaccine is effective in preventing certain strains of HPV, it does not eliminate the risk of all HPV types. Practicing good hygiene, avoiding direct contact with warts, and keeping the area clean can help minimize the risk of transmission.

In summary, post-treatment changes in the skin after viral wart removal can include hardening or thickening of the skin, which is often part of the healing process. If there are no signs of infection and the area remains stable, it may be best to monitor it. Always consult with your healthcare provider if you have concerns or if the situation changes.

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