Sudden Decline in Kidney Function: Causes and Concerns - Internal Medicine

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Acute decline in renal function?


At the end of the year, my health check revealed a blood urea nitrogen level of 13, creatinine level of 1.7, urine protein negative, specific gravity of 1.030, and blood pressure of 126/71.
Over the past years, my health check results have remained relatively stable, with only slight fluctuations in blood pressure.
This year, however, my creatinine level has exceeded the normal range, which shocked me.
My diet has not changed significantly compared to previous years.
I would like to ask the doctor:
1.
During my health check at the beginning of last year, I was found to have low vitamin D levels.
However, my job involves mostly outdoor work.
Could this still cause low vitamin D levels?
2.
I experienced diarrhea for about a month before this health check, and my bowel movements have been unpredictable.

3.
My weight has dropped from 72 kg in previous checks to 67 kg now.

Are the aforementioned factors the main reasons for my declining kidney function? Additionally, I had a period of diarrhea before this year-end check, which has affected my bowel movement regularity.

TIM, 30~39 year old female. Ask Date: 2022/01/25

Dr. Wu Jiyu reply Internal Medicine


According to your inquiry: 1.
If the health check has confirmed low vitamin D levels, please proceed with vitamin D supplementation.
2.
If you experienced diarrhea about a month prior to the health check, it is indeed possible that dehydration may have caused changes in kidney function.
It is recommended to stabilize your gastrointestinal system before re-evaluating.
Thank you for your inquiry.
The Nephrology Department of Changhua Hospital cares about you.

Reply Date: 2022/01/25

More Info


The sudden decline in kidney function can be alarming, especially when previous tests showed stable results. Based on your recent lab results, including a blood urea nitrogen (BUN) level of 13 mg/dL and a creatinine level of 1.7 mg/dL, it is understandable that you are concerned. Let's break down the potential causes and implications of these changes in kidney function.

1. Understanding Kidney Function Decline: The kidneys play a crucial role in filtering waste products from the blood, regulating electrolytes, and maintaining fluid balance. A sudden increase in creatinine levels, as you have experienced, can indicate acute kidney injury (AKI). This can occur due to various factors, including dehydration, infections, medications, or underlying health conditions.

2. Possible Causes of Your Kidney Function Decline:
- Dehydration: You mentioned experiencing diarrhea for about a month prior to your recent tests. Diarrhea can lead to significant fluid loss, resulting in dehydration, which can impair kidney function. When the body is dehydrated, the kidneys may not receive enough blood flow, leading to an increase in creatinine levels.

- Dietary Factors: While you noted that your diet has remained consistent, any changes in your fluid intake or dietary habits could impact kidney function. For instance, if you have been consuming less water due to gastrointestinal issues, this could exacerbate dehydration.

- Vitamin D Levels: You mentioned having low vitamin D levels previously. Vitamin D is essential for overall health, including kidney function. However, working outdoors typically increases exposure to sunlight, which helps the body produce vitamin D. If you are still experiencing low levels, it may be worth investigating further, as vitamin D deficiency can have various health implications, including potential impacts on kidney health.

3. Weight Loss and Its Implications: Your weight has decreased from 72 kg to 67 kg, which could be a concern. Unintentional weight loss can indicate underlying health issues, including malnutrition or chronic illness. It is essential to monitor your weight and discuss any significant changes with your healthcare provider.

4. Monitoring and Follow-Up: Given your recent changes in kidney function, it is crucial to have regular follow-up appointments with your healthcare provider. They may recommend additional tests, such as urine analysis, imaging studies, or blood tests, to further evaluate your kidney function and identify any underlying issues.

5. Lifestyle Modifications: To support kidney health, consider the following:
- Hydration: Ensure you are drinking enough fluids, especially if you have experienced diarrhea. Staying well-hydrated is essential for kidney function.

- Diet: Focus on a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Limiting processed foods and reducing sodium intake can also benefit kidney health.

- Monitoring Blood Pressure: Regularly check your blood pressure, as hypertension can further strain the kidneys. If your blood pressure remains elevated, discuss management strategies with your healthcare provider.

In conclusion, the sudden decline in your kidney function could be attributed to several factors, including dehydration from diarrhea, dietary habits, and potential underlying health issues. It is essential to work closely with your healthcare provider to monitor your kidney function, address any concerns, and implement lifestyle changes that promote kidney health. Regular follow-ups and open communication with your healthcare team will be crucial in managing your kidney health effectively.

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