Does Finasteride for Male Pattern Baldness Cause Stomach Ulcers? - Gastroenterology and Hepatology

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The medication finasteride, used for the treatment of male pattern baldness, is not commonly associated with causing gastric ulcers?


I have been taking finasteride for the treatment of male pattern baldness for about 3-4 years.
Does it cause gastric ulcers? Can I continue taking it? Additionally, I am using a topical medication for nail fungus; does it have any impact on gastric ulcers? I believe my lifestyle and diet are normal, as I do not drink tea or coffee, do not smoke or consume alcohol, and have no infection with Helicobacter pylori.
Therefore, the remaining potential causes seem to be psychological stress and medication use.
I would like to consult a physician to identify the causes of my gastric ulcers, aside from medication treatment.

Eric Chen, 50~59 year old female. Ask Date: 2022/02/01

Dr. Chen Shidian reply Gastroenterology and Hepatology


There should be no correlation.
However, please remain vigilant for any changes in related symptoms.

Reply Date: 2022/02/01

More Info


Finasteride, commonly prescribed for male pattern baldness, is primarily a 5-alpha-reductase inhibitor that works by blocking the conversion of testosterone to dihydrotestosterone (DHT). While it is generally well-tolerated, it is important to understand its potential side effects and interactions with other medications, especially in the context of gastrointestinal health.

Regarding your concern about whether finasteride can cause stomach ulcers, the evidence does not strongly support a direct link between finasteride and the development of gastric ulcers. Most studies and clinical data suggest that finasteride does not have significant gastrointestinal side effects. However, every individual may react differently to medications, and factors such as existing gastrointestinal conditions, concurrent medications, and overall health can influence the risk of developing ulcers.

You mentioned that you are also using topical treatments for nail fungus. Most topical antifungal medications are unlikely to have a direct effect on the stomach or contribute to ulcer formation, as they are applied externally and have minimal systemic absorption. However, if you are using oral antifungal medications, it would be prudent to discuss their potential side effects with your healthcare provider, as some oral antifungals can have gastrointestinal effects.

Given your healthy lifestyle—maintaining a balanced diet, avoiding caffeine, alcohol, and tobacco, and not having an infection with Helicobacter pylori—it seems that you are taking proactive steps to minimize ulcer risk. Psychological stress can indeed contribute to gastrointestinal issues, including ulcers, as stress can increase stomach acid production and affect gut motility. Therefore, managing stress through relaxation techniques, therapy, or lifestyle changes may be beneficial.

If you are experiencing symptoms of a stomach ulcer, such as persistent abdominal pain, bloating, or changes in bowel habits, it is essential to consult with a healthcare professional. They may recommend diagnostic tests, such as an endoscopy, to assess the condition of your stomach lining and rule out other potential causes of your symptoms.

In terms of continuing finasteride, if you have been taking it for several years without significant side effects, it may be reasonable to continue, especially if you are satisfied with the results for hair loss. However, it is crucial to have regular check-ups with your healthcare provider to monitor your overall health and any potential side effects from your medications.

In summary, while finasteride is not commonly associated with stomach ulcers, individual responses can vary. It is advisable to maintain open communication with your healthcare provider regarding all medications you are taking and any gastrointestinal symptoms you may experience. They can help you determine the best course of action, including whether to continue finasteride or explore alternative treatments for your hair loss. Additionally, addressing any psychological stressors and ensuring a healthy lifestyle can further support your gastrointestinal health.

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