Hair Loss: Finasteride Effects and Male Hormone Levels - Urology

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Hair loss issues


I'm sorry, doctor.
I would like to ask you about my experience in college when I was very anxious and felt a lot of pressure, which led to hair loss at the front of my scalp.
Later, I started taking finasteride 5/4 mg daily, and it seems that my hair loss has stopped.
However, could this cause a decrease in male hormones? I noticed that one of the side effects of the medication is breast tenderness, and I seem to have persistent breast fullness along with a bit of a belly.

Wei Wei, 30~39 year old female. Ask Date: 2012/04/12

Dr. Lin Hexing reply Urology


Hello: The medication you are taking is indeed an effective treatment for male pattern baldness, as it is an inhibitor of the conversion of testosterone to its more potent form, dihydrotestosterone (DHT).
Breast swelling, erectile dysfunction, and decreased libido may be side effects, while the issue with your "tuna belly" is likely related to your diet and exercise levels.
Lastly, for concerns regarding hair loss, it would be best to consult a dermatologist.
Wishing you peace and happiness.

Reply Date: 2012/04/12

More Info


Finasteride is a medication commonly prescribed for male pattern baldness, also known as androgenetic alopecia. It works by inhibiting the enzyme 5-alpha-reductase, which converts testosterone into dihydrotestosterone (DHT). DHT is a potent androgen that is primarily responsible for hair loss in genetically predisposed individuals. By reducing DHT levels, finasteride can help to slow hair loss and even promote regrowth in some cases.

Regarding your concerns about the effects of finasteride on male hormone levels and potential side effects, it is important to understand how this medication interacts with the body's hormonal balance. While finasteride effectively reduces DHT levels, it does not significantly lower testosterone levels. In fact, some studies suggest that testosterone levels may actually increase slightly due to the decreased conversion to DHT. However, the reduction in DHT can lead to side effects in a minority of users.

Common side effects associated with finasteride include sexual dysfunction, such as decreased libido, erectile dysfunction, and ejaculation disorders. Additionally, some men may experience gynecomastia, which is the enlargement of breast tissue, leading to symptoms like breast tenderness or swelling. The phenomenon you described as "乳房凸凸" (breast protrusion) could be related to this side effect. It is essential to monitor these symptoms and discuss them with your healthcare provider, as they may require further evaluation or adjustment of your treatment plan.

As for the "鮪魚肚" (commonly referred to as a "beer belly" or abdominal fat), this is typically more related to lifestyle factors such as diet and exercise rather than the direct effects of finasteride. While hormonal changes can influence body fat distribution, maintaining a balanced diet and regular physical activity is crucial for managing weight and overall health.

If you are concerned about the side effects you are experiencing, it is advisable to consult with your healthcare provider. They can assess your symptoms and determine whether finasteride is the right choice for you or if an alternative treatment may be more suitable. Additionally, if you are considering combining finasteride with other supplements or treatments, such as biotin or pumpkin seed oil, it is essential to discuss this with your doctor to avoid potential interactions or compounded side effects.

In summary, while finasteride is effective for treating hair loss, it can have side effects, particularly related to sexual function and breast tissue changes. It is crucial to maintain open communication with your healthcare provider to ensure that your treatment plan aligns with your health goals and to address any concerns you may have about side effects or hormonal changes. Regular follow-ups can help monitor your progress and make necessary adjustments to your treatment as needed.

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