Cryotherapy After Cone Biopsy: Risks and Alternatives - Obstetrics and Gynecology

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Cryotherapy


After the Pap smear showed abnormalities, a biopsy confirmed severe dysplasia.
The physician recommended a cone biopsy.
Six months after the first excision, the follow-up Pap smear again showed abnormalities, leading to a second cone biopsy.
The physician also suggested performing cryotherapy after the wound has healed.
Could you please advise if there will be any potential complications from these treatments? Are there any alternative treatment options available?

doris, 30~39 year old female. Ask Date: 2003/07/08

Dr. Lü Lizheng reply Obstetrics and Gynecology


Hello! You did not clearly specify what issues arose from the follow-up Pap smear after the first excision.
If the first excision was not completely clean, it should have been resolved after the second excision.
Personally, I believe that cryotherapy is not absolutely necessary.
Please confirm the pathology reports from both cone biopsies to ensure that the excision was complete.
Generally, after an excision, if one becomes pregnant again, a minor procedure to tighten the cervix should be performed around four months into the pregnancy.
Additionally, after the excision, vaginal discharge may be slightly reduced.
Best wishes for your health from Dr.
Lu Li-Cheng, Department of Obstetrics and Gynecology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2003/07/08

More Info


Cryotherapy, or cryosurgery, is a medical procedure that involves the application of extreme cold to destroy abnormal tissues, such as precancerous cells or tumors. In the context of cervical health, it is often used after procedures like cone biopsies, especially when there are concerns about high-grade cervical lesions or cervical intraepithelial neoplasia (CIN).
After undergoing a cone biopsy, which is a surgical procedure to remove a cone-shaped section of tissue from the cervix, patients may be advised to undergo cryotherapy if there are still abnormal cells present. This recommendation typically follows a careful evaluation of the biopsy results, which in your case indicated severe cellular changes.

Risks and Potential Side Effects of Cryotherapy
1. Pain and Discomfort: Patients may experience cramping or discomfort during and after the procedure. This is usually mild and can be managed with over-the-counter pain relief medications.

2. Bleeding: Some bleeding is common after cryotherapy, particularly if the procedure was performed shortly after a cone biopsy. However, excessive bleeding should be reported to a healthcare provider.

3. Infection: As with any procedure that involves the cervix, there is a risk of infection. Patients are advised to monitor for signs of infection, such as fever, increased pain, or unusual discharge.

4. Cervical Stenosis: In some cases, cryotherapy can lead to scarring of the cervix, which may cause narrowing (stenosis). This can potentially affect future pregnancies or menstrual cycles.

5. Impact on Future Pregnancies: While many women go on to have healthy pregnancies after cryotherapy, there is a slight risk of complications such as preterm labor or cervical incompetence, particularly if significant cervical tissue has been removed.

6. Recurrence of Abnormal Cells: There is a possibility that the abnormal cells may return, necessitating further treatment. Regular follow-up with Pap smears and HPV testing is crucial to monitor cervical health.


Alternatives to Cryotherapy
If cryotherapy is not suitable or if you are concerned about its risks, there are alternative treatment options:
1. Loop Electrosurgical Excision Procedure (LEEP): This is a more extensive procedure that uses a thin wire loop heated by electric current to remove abnormal cervical tissue. It is often used for larger lesions or when there is a concern about cancer.

2. Laser Therapy: This technique uses focused light to destroy abnormal cells on the cervix. It can be an effective alternative for patients who may not be ideal candidates for cryotherapy.

3. Observation: In some cases, if the abnormal cells are not severe, doctors may recommend a watchful waiting approach with regular Pap tests and HPV testing to monitor for any changes.

4. Hysterectomy: For women who have completed their families or have severe cervical dysplasia that does not respond to other treatments, a hysterectomy may be considered.


Conclusion
It is essential to discuss your concerns and treatment options with your healthcare provider. They can provide personalized advice based on your medical history, the extent of the cellular changes, and your reproductive plans. Regular follow-up care is crucial to ensure any potential issues are addressed promptly. Remember, the goal of these treatments is to prevent the progression of cervical disease and maintain your overall health.

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