Monitoring Acute Kidney Injury: When to Seek Specialist Care - Internal Medicine

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Observation period for acute kidney injury?


Hello Dr.
Wu,
My mother has been hospitalized for two months due to a bacterial infection.
Initially, her kidney function was not very good, but prior to this hospitalization, her kidney function was normal.
After more than a month, her levels improved to below 1, but just before discharge, her blood test showed a rise to 1.2.
In her most recent follow-up, it increased to 1.7.
The attending physician mentioned that we should observe her for a month before the next appointment, but I am concerned that if this is acute kidney injury, a month might be too long.
The attending physician is from the infectious disease department; should we seek an evaluation from a nephrologist sooner? Thank you, Dr.
Wu.

Attached are the recent blood test results:
CREA: 1/4 - 0.921, 1/11 - 1.241, 2/1 - 1.232, 2/11 - 1.77
eGFR: 1/4 - 61, 1/11 - 43.28, 1/21 - 43.68, 2/11 - 28.7

Mr. Wang, 10~19 year old female. Ask Date: 2022/02/16

Dr. Wu Jiyu reply Internal Medicine


Based on your inquiry, you only mentioned a bacterial infection that required hospitalization for two months, without mentioning whether you have any underlying conditions such as hypertension, diabetes, or dyslipidemia.
If you do have these conditions, they should be managed first to stabilize your kidney function.
Given that your kidney function is still fluctuating, it is advisable to consult a nephrologist for further follow-up.
Thank you for your inquiry; the Nephrology Department at Changhua Hospital cares about your health.

Reply Date: 2022/02/16

More Info


Acute Kidney Injury (AKI) is a sudden decline in kidney function, which can occur due to various factors such as infections, medications, dehydration, or obstruction of the urinary tract. The condition is characterized by an increase in serum creatinine levels or a decrease in urine output. In your mother's case, her fluctuating creatinine levels (from 1.0 to 1.7 mg/dL) after a prolonged hospitalization for a bacterial infection raise concerns about the possibility of AKI.

Given the context of your mother's recent health issues, it is crucial to monitor her kidney function closely. The fact that her creatinine levels have risen again after initially improving suggests that her kidneys may still be under stress or that there may be an underlying issue that needs to be addressed. The normal range for serum creatinine is typically around 0.6 to 1.2 mg/dL, but this can vary based on factors such as age, sex, and muscle mass. Therefore, a creatinine level of 1.7 mg/dL is concerning and warrants further investigation.

Your primary care physician's recommendation to observe for a month may be appropriate in some cases, especially if the increase in creatinine is slight and there are no other alarming symptoms. However, given your concerns and the recent fluctuations in her kidney function, it may be prudent to seek a nephrology (kidney specialist) evaluation sooner rather than later. Nephrologists can provide a more in-depth assessment of kidney function and determine if any specific interventions are necessary.

In addition to monitoring serum creatinine, other tests such as urine analysis, imaging studies, and possibly a kidney biopsy may be warranted to assess the underlying cause of the kidney dysfunction. It is also essential to consider any other health conditions your mother may have, such as hypertension or diabetes, which can complicate kidney health.

Furthermore, if your mother experiences any symptoms such as swelling, decreased urine output, fatigue, or changes in blood pressure, it is crucial to seek medical attention immediately. These could be signs of worsening kidney function or other complications.

In summary, while the recommendation to observe for a month may be standard in some cases, your mother's fluctuating creatinine levels and recent hospitalization history suggest that a nephrology consultation may be beneficial. Early intervention can help prevent further kidney damage and improve her overall health outcomes. Always advocate for your loved one's health, and do not hesitate to seek a second opinion if you feel it is necessary.

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