Skin Reactions: Pain, Itching, and Redness After Treatment - Dermatology

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After applying the medication, the skin experiences stinging, itching, and redness?


I have had seborrheic dermatitis on my face for many years.
It improved for a while, but recently it flared up again, although the condition is mild.
I visited a different dermatology clinic than before, and after applying the prescribed ointment, the affected area became more severely painful, itchy, and red.
There is also increased flaking on my face, which has even affected my sleep.
I have only been using the medication for 1-2 days.
Should I stop the medication and return for a follow-up, or is this side effect a normal reaction? The ointment is "Renneng Mycin Cream" containing Isoconazole nitrate.

Min, 20~29 year old female. Ask Date: 2022/02/19

Dr. Wu Yuxin reply Dermatology


The ingredients in the ointment are not problematic; it may not be compatible with your constitution.
It is recommended to stop using the medication and consult with your physician.

Reply Date: 2022/02/19

More Info


When dealing with skin reactions such as pain, itching, and redness after treatment, it is essential to understand the underlying causes and appropriate management strategies. In your case, it appears that you have a history of seborrheic dermatitis, which can be exacerbated by various treatments, including topical medications.
Seborrheic dermatitis is a common skin condition characterized by red, flaky patches, and it often affects areas rich in oil glands, such as the face, scalp, and upper back. The condition can be triggered or worsened by stress, hormonal changes, weather conditions, and certain skin care products. When you applied the medication, it seems to have led to an increase in symptoms, which can be concerning.

The medication you mentioned, "人人黴淨乳膏" (Vagent Cream), containing Isoconazole nitrate, is an antifungal agent used to treat fungal infections. While it can be effective for certain skin conditions, it may not be suitable for everyone, especially if there is an underlying sensitivity or allergic reaction to the ingredients. The increased pain, itching, and redness you are experiencing could be a sign of irritation or an allergic reaction to the medication.

Here are some steps to consider:
1. Discontinue Use: If you notice that your symptoms are worsening after starting a new medication, it is advisable to stop using it immediately. Continuing to use a product that causes irritation can lead to further complications.

2. Consult Your Dermatologist: Since you have already seen a dermatologist, it is crucial to return for a follow-up appointment. Inform them about the adverse reactions you are experiencing. They can assess your skin condition and determine whether the medication is appropriate for you or if an alternative treatment is needed.

3. Symptom Management: In the meantime, you can manage the symptoms by keeping your skin moisturized with a gentle, fragrance-free moisturizer. Avoid using harsh soaps or scrubs that can further irritate your skin. Over-the-counter hydrocortisone cream may help reduce inflammation and itching, but consult your doctor before using it.

4. Monitor for Allergic Reactions: If you experience severe symptoms such as swelling, blistering, or widespread redness, seek immediate medical attention, as these could be signs of a more serious allergic reaction.

5. Patch Testing: If you have a history of skin sensitivities, consider discussing patch testing with your dermatologist. This can help identify specific allergens or irritants that may be contributing to your skin issues.

6. Lifestyle Modifications: Stress management, a balanced diet, and proper hydration can also play a role in skin health. Consider incorporating stress-reducing activities such as yoga or meditation into your routine.

7. Follow-Up Care: Regular follow-ups with your dermatologist are essential for managing chronic skin conditions like seborrheic dermatitis. They can provide tailored treatment plans and adjust medications as necessary.

In conclusion, while it is common to experience some degree of irritation when starting a new topical treatment, significant worsening of symptoms is not typical and should be addressed promptly. Always prioritize communication with your healthcare provider to ensure you receive the most appropriate care for your skin condition.

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