Will Hair Loss Stop After Discontinuing Certain Medications? - Dermatology

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Hair loss


Some oral medications can cause hair loss, such as sedatives, antiemetics, antidepressants, and lithium used for treating bipolar disorder.
I have taken these medications; will hair loss stop after discontinuing them?

Tom, 20~29 year old female. Ask Date: 2003/07/22

Dr. Zheng Lizhen reply Dermatology


Hello! Some oral medications can cause hair loss, but this phenomenon will gradually improve after discontinuing the medication.
Best wishes for health from Dr.
Cheng Li-Chen, Department of Dermatology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2003/07/22

More Info


Hair loss can indeed be a distressing side effect of certain medications, including antidepressants, antipsychotics, and mood stabilizers like lithium. The phenomenon is often referred to as drug-induced hair loss, and it can occur through various mechanisms, such as altering the hair growth cycle or affecting hormone levels.

When you discontinue these medications, the potential for hair regrowth largely depends on the specific drug involved and individual factors such as your overall health, genetics, and the duration of medication use. In many cases, once the offending medication is stopped, hair loss may begin to reverse, and hair may gradually return to its normal growth cycle. This process can take several months, as hair follicles typically have a growth cycle that includes phases of growth (anagen), rest (telogen), and shedding (catagen).
For instance, medications like lithium can affect the levels of dihydrotestosterone (DHT), a hormone linked to hair loss in androgenetic alopecia (male or female pattern baldness). If a medication lowers DHT levels, stopping it may lead to a rebound effect where DHT levels rise again, potentially exacerbating hair loss in those predisposed to androgenetic alopecia. However, this is not universally applicable to all medications, and the response can vary greatly among individuals.

In the case of medications like antidepressants or antipsychotics, the hair loss may not be permanent. Many patients report that their hair begins to regrow after discontinuation of the medication, although the timeline can vary. It is essential to consult with a healthcare provider before making any changes to your medication regimen, as they can provide guidance tailored to your specific situation and health needs.

Additionally, if you are experiencing hair loss due to medication, it may be beneficial to explore other supportive treatments. Nutritional support, such as ensuring adequate intake of vitamins and minerals known to support hair health (like biotin, zinc, and iron), can be helpful. Stress management techniques, improved sleep hygiene, and possibly topical treatments like minoxidil may also aid in promoting hair regrowth.

In summary, while discontinuing certain medications can lead to a cessation of drug-induced hair loss, the extent and speed of recovery can vary. It is crucial to have open discussions with your healthcare provider about your concerns and to explore all available options for managing hair loss effectively.

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