Do You Need Lifelong Treatment for Male Pattern Baldness? - Dermatology

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Medications for Hair Loss


Is it necessary to use oral finasteride and topical minoxidil for life to treat male pattern baldness? Will the side effects of finasteride persist after discontinuation?

Jun, 20~29 year old female. Ask Date: 2012/06/26

Dr. Wu Yuxin reply Dermatology


If you wish to maintain the effects of post-treatment therapy, it is indeed necessary to continue using it; otherwise, hair loss will persist.
The side effects of Rogaine will disappear after discontinuation, so there is no need to worry.

Reply Date: 2012/06/26

More Info


Male pattern baldness, also known as androgenetic alopecia, is a common condition that affects many men as they age. The treatment options for this condition typically include oral medications like finasteride (commonly known as Propecia) and topical solutions such as minoxidil (often referred to as Rogaine).
To address your question about whether lifelong treatment is necessary, the answer is generally yes. Both finasteride and minoxidil require continuous use to maintain their effectiveness. When these treatments are stopped, any hair regrowth that occurred during the treatment period is usually lost within a few months. This is because these medications do not cure male pattern baldness; rather, they manage the symptoms and slow down the progression of hair loss.
Finasteride works by inhibiting the conversion of testosterone to dihydrotestosterone (DHT), a hormone that contributes to hair loss in genetically predisposed individuals. When you stop taking finasteride, the levels of DHT will return to their normal state, and hair loss will resume at its natural rate. Studies have shown that about 80% of men who take finasteride experience some degree of hair regrowth or maintenance, but this benefit is contingent upon ongoing use.

Minoxidil, on the other hand, is a topical treatment that promotes hair growth by increasing blood flow to the hair follicles. Similar to finasteride, if you stop using minoxidil, any new hair growth will typically be lost, and the hair will revert to its previous state within a few months.

Regarding the side effects of finasteride, some men may experience sexual side effects, including decreased libido, erectile dysfunction, or ejaculation disorders. These side effects are generally reversible upon discontinuation of the medication. However, there is a small percentage of men who report persistent side effects even after stopping the medication, a condition sometimes referred to as post-finasteride syndrome. This phenomenon is still being researched, and the exact cause and prevalence are not fully understood.

In summary, if you are considering treatment for male pattern baldness with finasteride and minoxidil, be prepared for the possibility of lifelong use to maintain results. It is essential to have a thorough discussion with your healthcare provider about the potential benefits and risks associated with these treatments, including the management of side effects and the implications of discontinuing therapy. Regular follow-ups can help monitor your progress and make any necessary adjustments to your treatment plan.
In conclusion, while the prospect of lifelong treatment may seem daunting, many men find that the benefits of maintaining their hair and the associated improvements in self-esteem and quality of life outweigh the challenges of ongoing medication.

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