Ropaxin and Lokejian
Dear Dr.
Cheng,
1.
For patients who have shown significant improvement in male pattern baldness with oral Finasteride or topical Minoxidil, if they discontinue use, will the areas where fine hair has grown revert to being bald? If this assumption is true, does it mean that to improve male pattern baldness, one must use oral Finasteride or topical Minoxidil for a lifetime? Is there no definitive cure for male pattern baldness (meaning that after taking the medication, hair regrows, but stopping the medication does not lead to hair loss again)?
2.
For patients who have shown significant improvement with oral Finasteride or topical Minoxidil, can adhering to a regular routine and engaging in appropriate exercise reduce the amount of medication needed?
Thank you, Doctor, for taking the time to respond.
Xiao Zheng, 20~29 year old female. Ask Date: 2004/12/22
Dr. Zheng Lizhen reply Dermatology
Hello: 1.
Currently, to improve male pattern baldness, it is necessary to take Finasteride orally or use Minoxidil topically for a lifetime.
Once hair regrowth occurs, stopping the medication for about six months will gradually lead to hair loss again.
2.
For patients with significant improvement in male pattern baldness who are taking Finasteride or using Minoxidil, there is currently no evidence that regular routines and appropriate exercise can reduce the dosage of the medication.
Sincerely, Dr.
Cheng Li-Chen, Dermatology.
Reply Date: 2004/12/22
More Info
When it comes to understanding the effectiveness of Finasteride and Minoxidil in treating male pattern baldness (androgenetic alopecia), it’s essential to clarify a few key points regarding their mechanisms, expected outcomes, and the nature of male pattern baldness itself.
1. Do Finasteride and Minoxidil Permanently Cure Male Pattern Baldness?
Unfortunately, neither Finasteride nor Minoxidil offers a permanent cure for male pattern baldness. Both medications can effectively slow down hair loss and promote hair regrowth while they are being used, but their effects are not permanent. Finasteride works by inhibiting the enzyme 5-alpha-reductase, which converts testosterone into dihydrotestosterone (DHT), a hormone that contributes to hair loss in genetically predisposed individuals. Minoxidil, on the other hand, is a topical solution that promotes hair growth by increasing blood flow to hair follicles and prolonging the anagen (growth) phase of hair.
If a patient experiences significant improvement in hair density and regrowth while using these medications, discontinuing them typically leads to a reversal of these benefits. Hair that has regrown may fall out again, and the individual may return to their baseline level of hair loss. This process can begin as soon as a few months after stopping treatment. Therefore, for individuals seeking to maintain their hair regrowth, ongoing treatment is generally necessary.
2. Is Lifelong Use Required?
Given the nature of male pattern baldness, which is a progressive condition influenced by genetic and hormonal factors, lifelong use of Finasteride and/or Minoxidil is often recommended for sustained results. While some patients may experience a plateau in hair loss after several years, the underlying genetic predisposition remains, and hair loss can resume if treatment is stopped.
3. Can Lifestyle Changes Reduce Medication Use?
While maintaining a healthy lifestyle, including regular exercise and a balanced diet, can positively impact overall health and potentially support hair health, it is unlikely to significantly reduce the need for medication in individuals with male pattern baldness. These lifestyle changes may improve circulation and overall well-being, but they do not directly address the hormonal factors that contribute to hair loss. Therefore, while a healthy lifestyle is beneficial, it should not be seen as a substitute for pharmacological treatment in managing male pattern baldness.
In summary, while Finasteride and Minoxidil can provide significant benefits in treating male pattern baldness, they do not offer a permanent solution. Patients should be prepared for the possibility of lifelong treatment to maintain their results. Additionally, while lifestyle improvements can support overall health, they are not a replacement for the medications that directly target the hormonal causes of hair loss. If you have concerns about the long-term use of these medications or their side effects, it is advisable to discuss them with a healthcare provider who specializes in hair loss treatments.
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