Medication Side Effects: Salivation Issues with Rivotril and Others - Psychiatry

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Drug side effects


Hello Dr.
Chiu, I would like to inquire about a medication issue.
My mother is taking Rivotril (clonazepam) 2mg and receiving intramuscular injections of Vistacon (bromocriptine).
She is experiencing excessive salivation.
Could this be a side effect of the medications? Thank you.

A, 10~19 year old female. Ask Date: 2022/03/11

Dr. Qiu Junda reply Psychiatry


Hello.
The Vistaton injection may still have extrapyramidal symptoms.
Patients receiving Vistaton may experience tremors, rigidity, and drooling, among other symptoms.
If you are referring to excessive salivation, it could be considered a side effect of the medication.
It is important to discuss this in detail with your attending physician.
Thank you.

Reply Date: 2022/03/11

More Info


Rivotril, known generically as clonazepam, is a medication primarily used to treat anxiety disorders, panic disorders, and certain types of seizures. While it can be effective for these conditions, it is important to be aware of its potential side effects, including excessive salivation, which can be a concern for some patients.

Excessive salivation, or sialorrhea, can occur as a side effect of various medications, including benzodiazepines like Rivotril. This side effect is not extremely common but can happen, particularly in sensitive individuals or those taking higher doses. The mechanism behind this side effect is not entirely understood, but it may be related to the drug's effects on the central nervous system and its interaction with neurotransmitters that regulate salivation.

In your mother's case, the combination of Rivotril and other medications, such as the muscle relaxant (维思通, or possibly a muscle relaxant like methocarbamol or similar), could also contribute to this issue. Muscle relaxants can sometimes lead to changes in muscle tone and function, which may indirectly affect salivary gland function and lead to increased salivation.
It is also worth noting that certain medications, particularly those that affect the autonomic nervous system, can lead to changes in salivation. For instance, medications that have anticholinergic properties typically reduce salivation, while others may increase it. If your mother is taking multiple medications, it is essential to consider the cumulative effects of these drugs.

If excessive salivation is causing discomfort or impacting her quality of life, it is advisable to consult her healthcare provider. They may consider adjusting her medication regimen or exploring other options to manage this side effect. In some cases, medications specifically designed to reduce salivation, such as anticholinergic agents, may be prescribed.

In summary, while excessive salivation can be a side effect of Rivotril and other medications, it is essential to evaluate the entire medication regimen and consider individual patient factors. Open communication with her healthcare provider is crucial to address any side effects and ensure that her treatment plan is both effective and tolerable. If the salivation issue persists or worsens, a thorough review of her medications and potential alternatives should be undertaken.

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