Condyloma Acuminatum: Pathology Report Insights - Obstetrics and Gynecology

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Cauliflower (Condylomata Acuminata) Report


Hello Doctor, I would like to ask if my pathology slide shows condyloma acuminatum (genital warts).
Thank you, Doctor.
Gross Description: Specimen received, labeled as perineal region, consists of two pieces of gray-white formalin-fixed tissues, measuring up to 0.2 x 0.1 x 0.1 cm in greatest dimension.
All for section.
Microscopic Description: Microscopically, the sections show polypoid structures composed of delicate fibrovascular cores lined by mature squamous epithelium.
There is no evidence of malignancy in the sections examined.

Xiao Qi, 30~39 year old female. Ask Date: 2022/04/13

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it seems that cauliflower was not mentioned.
Wishing you good health.

Reply Date: 2022/04/13

More Info


Condyloma acuminatum, commonly known as genital warts, is a benign epithelial tumor caused by the human papillomavirus (HPV). Your pathology report indicates that the specimen received from the perineal region consists of two small pieces of tissue that were fixed in formalin and examined microscopically. The gross description notes that the specimens are gray-white and small in size, which is typical for condyloma acuminatum lesions.

The microscopic description reveals that the sections show polypoid structures, which are characteristic of condyloma acuminatum. These structures are composed of a delicate fibrovascular core lined by mature squamous epithelium. The presence of mature squamous epithelium suggests that the lesions are benign and not indicative of malignancy. Importantly, the report states that there is no evidence of malignancy in the sections examined, which is a reassuring finding.

Condyloma acuminatum is typically associated with HPV types 6 and 11, which are considered low-risk types for cancer. While these warts can be bothersome and may recur, they are not cancerous and do not pose a significant risk of developing into cancer. However, it is essential to note that other high-risk HPV types can lead to more severe conditions, including cervical cancer, so regular screenings and discussions with your healthcare provider about HPV vaccination and safe practices are advisable.

In terms of management, treatment options for condyloma acuminatum include topical therapies, cryotherapy, laser treatment, and surgical excision, depending on the size and number of lesions. Since your pathology report indicates that the lesions are benign, you may not require aggressive treatment, but it is essential to follow up with your healthcare provider to determine the best course of action based on your specific situation.

Additionally, it is crucial to discuss any concerns you may have regarding HPV and its implications for your sexual health and the health of your partners. HPV is a common sexually transmitted infection, and while many people clear the virus without any issues, some may develop warts or, in rare cases, precancerous lesions. Therefore, maintaining open communication with your healthcare provider about your sexual health and any changes you may notice is vital.

In summary, your pathology report indicates that you have condyloma acuminatum, which is a benign condition with no evidence of malignancy. While it can be treated effectively, it is essential to have ongoing discussions with your healthcare provider regarding management options and preventive measures, including HPV vaccination and regular screenings. If you have any further questions or concerns, do not hesitate to reach out to your healthcare team for guidance and support.

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