Squamous Papilloma: Is It a Sexually Transmitted Infection? - Obstetrics and Gynecology

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Pathology report slice: Squamous papilloma


Is squamous papilloma, as indicated in the pathology report, a type of sexually transmitted infection? Is it contagious? How should it be treated? Last June, my HPV test showed no infection with any type of virus, and my Pap smear was normal this March.
Given the diagnosis of squamous papilloma, do I still need to undergo HPV DNA testing?

Xu Zishan, 30~39 year old female. Ask Date: 2022/04/14

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, you may consider undergoing electrosurgery or cryotherapy for the cervix, and you might also consider having another HPV test.
Wishing you good health.

Reply Date: 2022/04/14

More Info


Squamous papilloma is a benign epithelial tumor that typically appears as a wart-like growth on the skin or mucous membranes. It is important to clarify that squamous papilloma itself is not classified as a sexually transmitted infection (STI). However, it can be associated with the human papillomavirus (HPV), which is a well-known STI.
HPV is a group of more than 200 related viruses, and certain types of HPV are known to cause squamous papillomas, particularly in the genital area. While squamous papillomas can occur in various locations on the body, those that appear in the genital region may be linked to HPV types that are sexually transmitted. Therefore, while squamous papilloma itself is not an STI, its association with HPV means that it can be related to sexual activity.

In terms of transmission, squamous papillomas can be caused by HPV, which is primarily transmitted through direct skin-to-skin contact, including sexual contact. If a person has a squamous papilloma caused by HPV, there is a potential risk of transmitting the virus to sexual partners. However, not all squamous papillomas are caused by sexually transmitted HPV strains, and many are benign and do not pose a risk of transmission.

Regarding treatment, squamous papillomas are often removed if they cause discomfort, are cosmetically undesirable, or if there is any uncertainty about their nature. Treatment options may include surgical excision, cryotherapy (freezing), or laser therapy. It is essential to consult with a healthcare provider for an accurate diagnosis and appropriate treatment plan.

Since you mentioned that your HPV test last year was negative and your Pap smear was normal this year, it is a positive indication that you are not currently infected with high-risk HPV types. However, if squamous papilloma has been diagnosed, it may be prudent to discuss with your healthcare provider whether further HPV DNA testing is necessary. This is particularly relevant if the squamous papilloma is located in the genital area, as certain HPV types are associated with a higher risk of cervical cancer.

In summary, while squamous papilloma itself is not classified as a sexually transmitted infection, it can be associated with HPV, which is an STI. The potential for transmission exists, particularly if the papilloma is caused by a sexually transmitted strain of HPV. Regular screenings and consultations with a healthcare provider are essential for monitoring and managing any concerns related to HPV and squamous papillomas. If you have any further questions or concerns, it is advisable to seek guidance from a healthcare professional who can provide personalized advice based on your medical history and current health status.

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