How to Distinguish Between Normal Pearly Papules and Warts? - Urology

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How to distinguish between normal skin tags and warts?


Hello Doctor, I would like to ask about the small growths or bumps that appear in the coronal sulcus of the glans.
How can I differentiate whether they are normal and harmless or early symptoms of genital warts? I have looked at some descriptions of genital wart symptoms online, but I really cannot distinguish between the two.
Thank you.

Dà Xióng, 20~29 year old female. Ask Date: 2003/08/04

Dr. Liu Jianting reply Urology


It can indeed be difficult to distinguish! However, if you notice some "small growths" after having sexual contact, you should be cautious as they may be a sign of genital warts.
It's advisable to consult a urologist for an evaluation.

Reply Date: 2003/08/04

More Info


When it comes to distinguishing between normal pearly papules and warts, particularly in the context of genital health, it is essential to understand the characteristics of each condition. Pearly papules, also known as pearly penile papules, are small, dome-shaped, and typically white or skin-colored bumps that appear around the corona of the glans (the head of the penis). They are completely benign and are considered a normal anatomical variant. These papules are often mistaken for sexually transmitted infections (STIs) due to their appearance, but they are not contagious and do not require treatment.

On the other hand, genital warts, which are caused by certain strains of the human papillomavirus (HPV), can appear as small, flesh-colored or gray growths that may be raised or flat. They can occur in clusters and may have a cauliflower-like appearance. Unlike pearly papules, genital warts are contagious and can be transmitted through sexual contact. They may also cause discomfort, itching, or bleeding, especially if they become irritated.

To differentiate between the two, consider the following factors:
1. Location and Appearance: Pearly papules are typically found in a single row around the corona of the glans and are uniform in size and shape. Genital warts can appear anywhere in the genital area and may vary in size and shape, often presenting in clusters.

2. Symptoms: Pearly papules are asymptomatic, meaning they do not cause any pain, itching, or discomfort. In contrast, genital warts may be itchy or painful, especially if they are irritated or if they bleed.

3. Duration: Pearly papules are a permanent feature that does not change over time, while genital warts can grow, multiply, or change in appearance.

4. Medical Evaluation: If there is any doubt about the nature of the growths, it is advisable to consult a healthcare provider for a proper evaluation. A dermatologist or urologist can perform a visual examination and may conduct further tests, such as a biopsy, if necessary.

5. Risk Factors: Understanding your sexual health history is crucial. If you have had multiple sexual partners or unprotected sex, you may be at a higher risk for HPV and, consequently, genital warts.

In summary, while pearly papules are harmless and a normal variant, genital warts are a sign of an STI and require medical attention. If you are uncertain about the growths you are experiencing, it is best to seek professional medical advice. A healthcare provider can provide a definitive diagnosis and discuss potential treatment options if necessary. Remember, early detection and treatment of STIs are vital for maintaining sexual health and preventing complications.

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