Post-COVID Complications: Antinuclear Antibody Levels - Pulmonology

Share to:

Post-COVID-19 diagnosis, anti-nuclear antibodies +160?


Hello Dr.
Wang, I was infected while dining at a restaurant on January 9 of this year and was subsequently taken to Taoyuan Min-Sheng Hospital.
Upon arrival, my CT value was 18.
Ten days later, my first test result was 41.4 and the second was 44, after which I was discharged.
After discharge, I developed severe red rashes on the soles of my feet that resembled blisters.
I have a history of chronic urticaria and mild dyshidrotic eczema when under stress, so I initially thought it was due to the stress of being in the hospital, especially since my colleagues were also affected.
I was still working in the hospital without proper rest, which I believed contributed to the issue.
At first, I didn't pay much attention to it, but it gradually worsened.
The blisters would subside but then lead to peeling skin, and they only appeared on the sole of my left foot and both hands.
A general clinic diagnosed it as dyshidrotic eczema, but it has not been confirmed whether it is caused by the COVID-19 virus.
I later visited the pulmonary medicine and dermatology departments at the hospital for ongoing monitoring.
The doctor drew blood and tested for antinuclear antibodies, which returned a positive result of 160, indicating a disorder in my antibody production, but it is uncertain if it is related to the COVID-19 virus.
I have been advised to apply medication for discomfort and take medication when it becomes severe.
I would like to ask if this data requires follow-up visits, and which department should I consult?

Huang, 40~49 year old female. Ask Date: 2022/04/19

Dr. Wang Lanfeng reply Pulmonology


Hello: Based on your description, the rash and blisters on your palms and hands could indeed be due to an immune response.
However, it is currently difficult to determine whether they are caused by the COVID-19 virus.
Given that your ANA is greater than 160, I recommend that you visit a rheumatology and immunology clinic for further evaluation.
Thank you.

Reply Date: 2022/04/19

More Info


Hello, thank you for your question regarding post-COVID complications and antinuclear antibody (ANA) levels. It seems that you have experienced a series of health challenges following your COVID-19 infection, including skin issues and a positive ANA test. Let’s break down your concerns and provide some clarity.

1. Understanding Antinuclear Antibody (ANA) Levels: The presence of ANA in your blood indicates that your immune system may be producing antibodies that mistakenly target your own cells. A positive ANA test can be associated with various autoimmune diseases, including lupus, rheumatoid arthritis, and others. However, a positive result alone does not confirm a diagnosis of an autoimmune disease. It is essential to interpret these results in conjunction with clinical symptoms and other laboratory findings.

2. Post-COVID Complications: After a COVID-19 infection, some individuals experience lingering symptoms, often referred to as "Long COVID." These can include fatigue, joint pain, skin rashes, and other systemic issues. The skin problems you described, such as the red rashes and blisters, could potentially be linked to your COVID-19 infection, but they may also be exacerbated by stress or other factors. Chronic urticaria (hives) and sweat dermatitis (sweat blisters) can be triggered by various stressors, including infections.

3. Need for Follow-Up: Given that your ANA level is positive and you are experiencing significant skin symptoms, it is advisable to continue monitoring your condition. Regular follow-ups with a healthcare provider are essential to assess any changes in your symptoms and to determine if further testing is needed. It may be beneficial to consult with a rheumatologist, as they specialize in autoimmune diseases and can provide a more comprehensive evaluation of your ANA results in the context of your symptoms.

4. Specialist Consultation: Since you have skin manifestations, it would also be prudent to continue working with a dermatologist. They can help manage your skin symptoms and determine if they are indeed related to an autoimmune process or if they are a separate issue. A multidisciplinary approach may be beneficial, involving both a rheumatologist for the autoimmune aspect and a dermatologist for the skin concerns.

5. Monitoring and Management: It is important to keep track of any new symptoms or changes in your condition. If you notice worsening symptoms or new issues arise, do not hesitate to seek medical attention. Treatment for autoimmune conditions can vary widely, and early intervention can often lead to better outcomes.

In summary, your positive ANA test and the skin symptoms you are experiencing warrant further evaluation and monitoring. It is advisable to maintain regular follow-ups with your healthcare providers, including a rheumatologist and a dermatologist, to ensure that you receive appropriate care and management for your condition. Additionally, managing stress and maintaining a healthy lifestyle can also support your overall well-being during this recovery phase. Thank you for reaching out, and I hope this information helps guide your next steps in managing your health.

Similar Q&A

Understanding RA Factor Changes and Related Health Concerns

Hello, Doctor Gao. I apologize for the lengthy message. Here are my health examination data from three tests conducted at the same laboratory: - Date: 2023/11/11, 2024/6/15, (2024/4/30) - ALT/SGPT (Liver Enzyme): 29, 46 - AST/SGOT (Liver Enzyme): 20, 26 - RA (Rheumatoid Factor)...


Dr. Gao Jiankai reply Internal Medicine
Hello, thank you for your inquiry. Here are my responses: 1. I underwent tests related to immune system diseases at a regional hospital in December 2023, and my rheumatoid arthritis (RA) factor was less than 5 at that time. Additionally, the measurement taken on April 30, 2024,...

[Read More] Understanding RA Factor Changes and Related Health Concerns


Understanding the Link Between Gamma-Globulin Levels and Multiple Myeloma

Hello, doctor. I was diagnosed with COVID-19 on June 10. After that, on June 25, I developed petechiae on my calves due to an immune response. I sought medical attention, and it was assessed as vasculitis. Blood tests and urinalysis were all normal. After taking steroids for one ...


Dr. Chen Yunfang reply Oncology
Hello: You have undergone many tests, including some uncommon ones, which were not originally conducted due to a suspicion of multiple myeloma. Therefore, it is quite strange to force a connection to that. The diagnosis of multiple myeloma can only be made through a bone marrow a...

[Read More] Understanding the Link Between Gamma-Globulin Levels and Multiple Myeloma


Understanding Post-COVID Symptoms: Yellow Nasal Discharge and Vasculitis Concerns

Hello, doctor. About two weeks ago, I tested positive for COVID-19, and approximately four days ago, I suddenly developed numerous petechiae on my calves. I went to the hospital's dermatology department for an examination, where they performed blood tests and a urinalysis. A...


Dr. Zheng Jueyi reply Otolaryngology
Hello, if all immune-related blood tests are normal and there is no history of rheumatologic or autoimmune diseases, along with no significant abnormalities found during the endoscopic examination, the likelihood of developing vasculitis is very low. It may be advisable to either...

[Read More] Understanding Post-COVID Symptoms: Yellow Nasal Discharge and Vasculitis Concerns


Understanding Elevated White Blood Cell Count: Causes and Next Steps

Hello, doctor. First, I would like to inform you that I am a patient with myasthenia gravis. I am currently taking four tablets of Mestinon daily and one tablet of Anspine weekly. Here are my questions: Since mid-September, I have been infected with a common cold from my child an...


Dr. Liao Zhongxin reply Internal Medicine
1. First, we are currently in the era of COVID-19, so it is essential to rule out this possibility by conducting a self-administered rapid test and receiving the COVID-19 vaccine (at least four doses are recommended). 2. Secondly, the side effects of medications should also be c...

[Read More] Understanding Elevated White Blood Cell Count: Causes and Next Steps


Related FAQ

Covid-19

(Pulmonology)

Covid-19 Vaccine

(Pulmonology)

After Covid-19 Vaccination

(Cardiology)

Allergies

(Pulmonology)

Covid-19

(Influenza)

Covid-19 Diagnosis

(Internal Medicine)

Pneumonia

(Pulmonology)

Computed Tomography

(Pulmonology)

Bronchiectasis

(Pulmonology)

Covid-19

(Family Medicine)