Managing Eye Pressure and Blood Pressure: Concerns During Pregnancy - Ophthalmology

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Hello, doctor.
I would like to ask about my situation.
I have an intraocular pressure of 24 and my myopia is between 900 and 1000.
I have been using Aifume for three months now, and I have been returning for follow-up visits with OCT and visual field tests.
My intraocular pressure is now 19, which is normal.
I checked the side effects of Aifume, and it mentions lowering blood pressure.
My blood pressure is usually around 95/65, sometimes 100/70.
I am still using this medication to maintain normal intraocular pressure, but I find it contradictory.
Although my intraocular pressure has decreased, if my blood pressure is low, could it not also affect the circulation in my eyes? Could it potentially worsen blood circulation? (I am currently pregnant and concerned about the effects of the medication on the fetus, so I discussed with my doctor and decided to continue using Aifume, which is classified as a Category B medication.)

Jun, 30~39 year old female. Ask Date: 2022/04/23

Dr. He Jianxian reply Ophthalmology


If there are concerns about the adverse effects of medication on the fetus, temporarily discontinuing the medication and resuming it once the fetus is larger could be a reasonable option.
Regarding intraocular pressure-lowering medications, there is a possibility that they may also lower blood pressure; however, this effect is generally not significant unless there is a noticeable drop in blood pressure accompanied by symptoms.
Therefore, this issue may not need to be overly concerned about.
Director He Jianxian, Department of Ophthalmology, Nantou Hospital.

Reply Date: 2022/04/23

More Info


Managing eye pressure and blood pressure during pregnancy is a complex issue that requires careful consideration of both maternal and fetal health. As you mentioned, you have been diagnosed with elevated eye pressure and high myopia, and you are currently using a medication called Alphagan (commonly referred to as "艾弗目" in Chinese) to manage your eye pressure. It's important to understand the implications of using this medication during pregnancy, especially given your concerns about its effects on blood pressure and fetal health.

Alphagan is classified as a Category B medication by the FDA, which means that animal studies have not shown any risk to the fetus, but there are no well-controlled studies in pregnant women. This classification suggests that while the medication may be relatively safe, it is still crucial to weigh the benefits against potential risks. In your case, maintaining normal eye pressure is essential to prevent damage to your optic nerve and preserve your vision, particularly given your history of high myopia.

You raised a valid concern about the potential side effects of Alphagan, particularly its ability to lower blood pressure. Your baseline blood pressure readings of 95/65 mmHg are on the lower side of normal, and while this may not pose an immediate risk, it is essential to monitor for any symptoms of hypotension, such as dizziness, fainting, or fatigue. Low blood pressure can indeed affect ocular circulation, potentially leading to insufficient blood flow to the eyes, which could exacerbate your existing eye conditions.

During pregnancy, hormonal changes can affect both blood pressure and eye pressure. For example, progesterone can cause blood vessels to relax, which may lead to lower blood pressure. Additionally, fluid retention and increased blood volume during pregnancy can influence eye pressure. Therefore, it is crucial to have regular check-ups with both your ophthalmologist and obstetrician to monitor these parameters closely.

If you are concerned about the effects of Alphagan on your pregnancy, it may be worth discussing alternative treatment options with your ophthalmologist. Some medications for glaucoma are considered safer during pregnancy, and your doctor can help you weigh the risks and benefits of continuing with Alphagan versus switching to another medication or temporarily discontinuing treatment.
Moreover, lifestyle modifications can also play a role in managing both eye pressure and blood pressure. Staying hydrated, maintaining a balanced diet, and engaging in regular, moderate exercise (as advised by your healthcare provider) can help support overall health during pregnancy.

In summary, managing eye pressure and blood pressure during pregnancy requires a collaborative approach between your eye care provider and obstetrician. Regular monitoring and open communication about your symptoms and concerns are essential to ensure both your health and the health of your baby. If you experience any new or worsening symptoms, such as increased eye pain or significant changes in vision, it is crucial to seek medical attention promptly.

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