Managing Diarrhea in Diabetic Patients: Causes and Solutions - Internal Medicine

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Diarrhea in diabetic patients


My father has been a diabetic patient for 30 years and is now 77 years old.
He controls his blood sugar with insulin injections.
His hemoglobin A1c levels have been normal during his quarterly check-ups.
However, since the beginning of March, he has suddenly started experiencing diarrhea without abdominal pain.
He underwent a colonoscopy, which showed no issues, and he has also switched anticoagulant medications, but there has been no improvement.
I am very worried and don't know what to do! What treatment should the doctor provide?
Reply from Dr.
Li Jian, Chiayi Hospital / Internal Medicine, 2022/04/27: The medications that are more likely to cause diarrhea among blood sugar medications are metformin and acarbose.
If the diarrhea is not caused by these medications, it is still necessary to follow up with a gastroenterologist.
Thank you, doctor! My father has been using NovoRapid and Toujeo insulin injections for twenty years.
Could you please advise us on how to address my father's issue? The gastroenterologist said he couldn't find the problem.
Who else can we consult? Thank you for your assistance.
🙏

Ye, 40~49 year old female. Ask Date: 2022/04/27

Dr. Li Jian reply Internal Medicine


If diarrhea persists, please visit the gastroenterology department at a medical center.
Thank you.

Reply Date: 2022/04/27

More Info


Managing diarrhea in diabetic patients can be a complex issue, particularly when the patient has a long history of diabetes, as in your father's case. Diarrhea can be caused by a variety of factors, including medication side effects, dietary changes, infections, and complications related to diabetes itself. Given your father's situation, let's explore the potential causes and solutions for his diarrhea.


Causes of Diarrhea in Diabetic Patients
1. Medication Side Effects: Certain diabetes medications, particularly Metformin and Acarbose, are known to cause gastrointestinal side effects, including diarrhea. However, since your father is using insulin (NovoRapid and Toujeo), it is less likely that his current medications are the direct cause unless there have been recent changes in his medication regimen.

2. Dietary Factors: Changes in diet can also lead to diarrhea. For diabetic patients, managing carbohydrate intake is crucial, but sometimes high-fiber foods or sudden changes in diet can upset the gastrointestinal tract.

3. Gastrointestinal Complications: Diabetes can lead to complications such as gastroparesis, which affects the stomach's ability to empty properly. This can result in symptoms like diarrhea, bloating, and nausea. Although your father has had a colonoscopy that showed no issues, it may be worthwhile to assess for other gastrointestinal conditions.

4. Infections: Gastrointestinal infections, whether viral, bacterial, or parasitic, can cause diarrhea. Given your father's age and health status, it’s important to rule out any infections that could be contributing to his symptoms.

5. Diabetic Enteropathy: This is a condition that can occur in long-standing diabetes, leading to altered bowel function and symptoms such as diarrhea.


Solutions and Management Strategies
1. Consult a Gastroenterologist: Since your father has already seen a gastroenterologist without a clear diagnosis, it may be beneficial to seek a second opinion or consult a specialist who focuses on diabetic complications. They may suggest additional tests, such as stool studies or imaging, to identify any underlying issues.

2. Review Medications: Discuss with your father's healthcare provider the possibility that his current medications could be contributing to his diarrhea. If he has recently switched anticoagulants, this could also be a factor. A medication review may lead to adjustments that could alleviate his symptoms.

3. Dietary Adjustments: Keeping a food diary can help identify any dietary triggers. It may be beneficial to work with a dietitian who specializes in diabetes management to ensure that his diet is balanced and not contributing to gastrointestinal distress.

4. Hydration and Electrolyte Management: Diarrhea can lead to dehydration, especially in older adults. Ensure that your father stays well-hydrated and consider electrolyte solutions if diarrhea persists.

5. Monitor Blood Sugar Levels: Since diarrhea can affect blood sugar levels, it’s important to monitor these closely. Fluctuations in blood sugar can lead to further complications, so maintaining stable levels is crucial.

6. Consider Probiotics: Some studies suggest that probiotics may help manage gastrointestinal symptoms in diabetic patients. Discuss this option with his healthcare provider to see if it might be appropriate for him.

7. Follow-Up Care: Regular follow-ups with his healthcare team are essential. If symptoms persist or worsen, further investigations may be warranted to ensure there are no serious underlying conditions.

In conclusion, managing diarrhea in diabetic patients requires a comprehensive approach that considers medication effects, dietary habits, and potential gastrointestinal complications. It’s important to work closely with healthcare providers to identify the root cause and develop an effective management plan tailored to your father's needs.

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