Muscle Twitches and Weakness: When to Seek Help - Neurology

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Muscle twitching


Recently, I have been experiencing muscle twitching that is not localized to a specific area.
Sometimes, I notice a decrease in strength in my left hand, and at other times, it shifts to my left hand and left leg.
After researching online, I came across the symptoms of amyotrophic lateral sclerosis (ALS), which has made me very scared and anxious.
I would like to ask the doctor if muscle weakness refers to being completely unable to lift objects, or does it mean a decrease in strength?

Travis, 10~19 year old female. Ask Date: 2022/05/02

Dr. Jiang Junyi reply Neurology


Hello Mr.
Travis,
You mentioned that "the strength in your hands has decreased, and sometimes the strength in your left hand and foot has also diminished..." Since these symptoms are on the same side, we should first rule out any cervical spine issues.
You are concerned about amyotrophic lateral sclerosis (ALS), which is a rare disease with a prevalence of 0.5 to 0.6 per 100,000 in Taiwan.
It primarily involves problems with motor neurons, which control muscle movement.
Generally, the motor neurons in the brain are referred to as upper motor neurons, while those in the brainstem and spinal cord are called lower motor neurons.

When motor neurons are affected, our muscles do not receive adequate nutrients and chemicals, which can lead to muscle death.
This is a chronic muscle-wasting disease that may cause muscle atrophy.
If upper motor neurons die, abnormal signal transmission can lead to muscle twitching.
The presence of lower motor neuron signs (muscle atrophy, weakness, and fasciculations) can almost confirm a diagnosis of motor neuron disease, especially when upper motor neuron reflexes such as enhanced tendon reflexes, the Hoffmann sign, and the Babinski reflex are observed in the same limb.

Clinical diagnosis typically requires electromyography (EMG) and muscle biopsy among other methods.
I recommend consulting a neurologist specializing in peripheral nerve disorders, as they have more experience with EMG diagnostics.
Thank you for your inquiry, and feel free to discuss any related questions! Wishing you good health, peace, and joy.
Dr.
Chien-Yi Jiang, Taoyuan Hospital

Reply Date: 2022/05/02

More Info


Muscle twitches and weakness can be concerning symptoms, especially when they occur intermittently and affect different parts of the body. It's understandable that you might feel anxious, particularly when you come across information about serious conditions like amyotrophic lateral sclerosis (ALS), commonly referred to as "Lou Gehrig's disease" or "渐冻症" in Chinese. However, it's essential to approach this situation with a clear understanding of muscle weakness and twitching, as well as when to seek medical help.

Muscle weakness can manifest in various ways. It may mean that you have difficulty lifting objects that you could previously manage with ease, or it could simply mean that your muscles feel fatigued or less powerful than usual. In your case, it seems that you are experiencing a fluctuation in strength, where sometimes your left hand feels weaker, and at other times, it's your left leg. This type of weakness can be due to several factors, including fatigue, overuse, or even anxiety, which can lead to muscle tension and perceived weakness.

Muscle twitching, or fasciculations, can occur for a variety of benign reasons, such as stress, caffeine intake, dehydration, or even muscle fatigue. These twitches are often harmless and can be a normal response of the muscle fibers. However, if they are persistent and accompanied by weakness, it could indicate an underlying neurological issue that warrants further investigation.

In the context of ALS, it's important to note that the disease typically presents with progressive muscle weakness and atrophy, often starting in one area of the body and spreading. Symptoms may include difficulty speaking, swallowing, or breathing, in addition to muscle twitching and weakness. However, the presence of muscle twitching alone, especially if it is not accompanied by significant weakness or atrophy, does not necessarily indicate ALS.

Given your symptoms, here are some recommendations:
1. Monitor Symptoms: Keep a detailed log of your symptoms, including when the twitching and weakness occur, their duration, and any other associated symptoms (like fatigue, pain, or changes in coordination). This information can be valuable for your healthcare provider.

2. Consult a Healthcare Provider: If your symptoms persist or worsen, it is crucial to seek medical attention. A neurologist can perform a thorough evaluation, which may include a physical examination, blood tests, electromyography (EMG), and possibly imaging studies to assess your muscle and nerve function.

3. Consider Stress and Lifestyle Factors: Sometimes, muscle twitching and weakness can be exacerbated by stress, anxiety, or lifestyle factors such as diet and hydration. Ensuring you are well-hydrated, managing stress through relaxation techniques, and maintaining a balanced diet can help alleviate some symptoms.

4. Avoid Self-Diagnosis: While it’s natural to search for answers online, self-diagnosing can lead to unnecessary anxiety. Many conditions can cause muscle twitching and weakness, and only a healthcare professional can provide an accurate diagnosis.

5. Physical Therapy: If weakness is affecting your daily activities, a physical therapist can help design a program to strengthen your muscles and improve function. They can also provide strategies to manage fatigue and improve overall mobility.

In summary, while muscle twitching and weakness can be concerning, they are not always indicative of a severe condition like ALS. It's essential to monitor your symptoms and consult with a healthcare professional for a proper evaluation and guidance. Early intervention can make a significant difference in managing any underlying issues and improving your quality of life.

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