Insomnia After Stopping Lorazepam: Causes and Solutions - Psychiatry

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Why does someone who originally did not have insomnia experience it after stopping medication?


I previously took Lorazepam 0.5 mg for over three months, and stopping the medication has caused insomnia that has lasted for more than nine months.
I can fall asleep quickly, but I wake up after 2 to 3 hours, and when I go back to sleep, it's only light sleep, making me feel increasingly tired.
Before taking the medication, I never had insomnia.
I don't know how long it will take to return to my previous state.
During this time, I switched to a different clinic and tried many non-benzodiazepine medications, but none were effective.
Initially, my doctor advised against resuming benzodiazepine medications, but he said I was suffering too much and prescribed them for backup.
However, I have resisted taking them and have only used half of a 25 mg Trazodone tablet.
I read some information online stating that withdrawal can lead to poor sleep in the latter half of the night, which may persist for months or even years.
Seeing this makes me unsure how much longer I can endure this or if I really need to return to Lorazepam or other benzodiazepines.
I hope the doctor can provide me with some answers; I would be very grateful.

Xiao Cheng, 30~39 year old female. Ask Date: 2022/05/03

Dr. Wang Yaoting reply Psychiatry


Hello: The dosage of Lorazepam 0.5 mg that you previously took is considered quite low.
This dosage primarily provides anxiolytic effects and should not lead to significant or prolonged withdrawal symptoms.
Insomnia may be related to your underlying condition or circadian rhythm issues.
It is recommended to make the following lifestyle adjustments:
1.
Maintain regular meals, ensure adequate sleep, and engage in moderate exercise: A good diet and sleep are fundamental to maintaining physical and mental health.
Sleep helps stabilize mood, and poor sleep often leads to fatigue and irritability.
Aim for at least 7 hours of sleep each night and incorporate regular exercise into your weekly routine to promote sweating.
Try to maintain a consistent daily schedule.
You can follow the 333 exercise method: exercise at least 3 times a week, for a minimum of 30 minutes each session, and ensure your heart rate reaches over 130 beats per minute after each workout.
2.
Develop effective stress-relief techniques: Regularly talk with friends, listen to music, sing, or get a massage, combined with diaphragmatic breathing.
Inhale slowly through your nose and exhale slowly through your mouth, doing this 20 times in the morning, afternoon, evening, and before bed, for a total of at least 80 times a day.
3.
Keep a mood journal before bed to reflect on and organize your emotions from the day, which can help alleviate tension and stress.
4.
Avoid stimulants such as tobacco, alcohol, tea, and coffee, and refrain from using your phone or watching TV before bedtime.
If symptoms persist without improvement, consider visiting a mental health clinic for alternative non-benzodiazepine medications combined with psychotherapy, which should yield good results.
I hope this answers your question :)

Reply Date: 2022/05/03

More Info


Understanding insomnia after discontinuing Lorazepam can be quite complex, especially given the nuances of individual responses to medication and the underlying psychological or physiological conditions that may contribute to sleep disturbances. Lorazepam, a benzodiazepine, is often prescribed for anxiety and sleep disorders, but long-term use can lead to dependence and withdrawal symptoms upon cessation, including insomnia.

When you stop taking Lorazepam after a prolonged period, your body may experience withdrawal symptoms, which can manifest as insomnia. The duration of these symptoms can vary significantly from person to person. In many cases, withdrawal-related insomnia may last for several weeks to a few months. However, some individuals report persistent sleep issues that can last for months or even years. This phenomenon is sometimes referred to as "protracted withdrawal syndrome," and it can be particularly distressing for those who previously had no sleep issues.

Your experience of falling asleep quickly but waking up after 2-3 hours, followed by shallow sleep, is not uncommon among those who have recently stopped benzodiazepines. This pattern may indicate that your body is still adjusting to the absence of the medication, which previously helped regulate your sleep architecture. Additionally, the anxiety or stress that may have prompted the initial prescription of Lorazepam could resurface, further complicating your sleep issues.

It's also important to consider the role of your autonomic nervous system. You mentioned experiencing gastrointestinal symptoms like stomach pain and nausea, which can be related to anxiety and stress. While these symptoms may have improved after stopping Lorazepam, the interplay between anxiety, sleep, and physical health can create a challenging cycle. Stress and anxiety can exacerbate insomnia, leading to a vicious cycle where poor sleep further increases anxiety levels.

In terms of treatment options, it’s crucial to approach this situation holistically. While it may be tempting to return to Lorazepam or another benzodiazepine for immediate relief, this could potentially lead to a cycle of dependence again. Instead, consider discussing with your healthcare provider the possibility of using longer-acting benzodiazepines, such as Clonazepam or Diazepam, which may be easier to taper off in the long run. However, any medication adjustments should be made under the guidance of a qualified healthcare professional.

In addition to pharmacological options, non-pharmacological interventions can be highly beneficial. Cognitive Behavioral Therapy for Insomnia (CBT-I) is a well-established treatment that focuses on changing sleep habits and misconceptions about sleep. Techniques such as sleep hygiene education, stimulus control therapy, and relaxation techniques can significantly improve sleep quality without the risks associated with medication.

Regular physical activity can also help regulate your autonomic nervous system and improve sleep quality. Aim for at least 30 minutes of moderate exercise most days of the week, but try to avoid vigorous exercise close to bedtime. Additionally, reducing caffeine and alcohol intake, especially in the hours leading up to sleep, can help improve sleep quality.

Lastly, consider seeking support from a sleep specialist or a mental health professional who can provide tailored strategies to address both your insomnia and any underlying anxiety or stress. They may also recommend alternative therapies, such as mindfulness or relaxation techniques, which can be effective in managing anxiety and improving sleep.

In summary, while the journey to overcoming insomnia after stopping Lorazepam can be challenging, a combination of appropriate medical guidance, behavioral therapies, and lifestyle modifications can lead to significant improvements in sleep quality and overall well-being. It’s essential to remain patient and persistent, as recovery from medication-induced insomnia can take time.

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I previously took Lorazepam 0.5 mg for over three months, and after stopping the medication, I have been experiencing insomnia for more than nine months. I can fall asleep quickly, but I wake up after 1 to 3 hours, and when I go back to sleep, it is very light sleep, making me fe...


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Hello, Xiao Cheng: Thank you for your hard work! It seems that your current insomnia may be a symptom of medication withdrawal. I recommend a gradual tapering approach to discontinue the medication, such as first reducing Lorazepam to half a tablet. If you can maintain stable sle...

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It may be advisable for users to consider using longer-acting benzodiazepines such as Clonazepam or Diazepam instead of Lorazepam, as they may facilitate easier discontinuation (but this should still be discussed with your physician), and to enhance sleep hygiene. Dr. Wu En-Liang...

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