Elevated Blood Test Results During Oocyte Freezing Process - Internal Medicine

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Blood test values


Hello doctor, I would like to ask about my blood test results on the second day of my menstrual period due to my egg freezing treatment.
My hemoglobin (HB) is 13.5, with a reference range of [10.1][12.7].
My mean corpuscular hemoglobin (MCH) is 31, with a reference range of [22.7][28.6].
My mean corpuscular volume (MCV) is 92.7, with a reference range of [69.5][85].
I am unsure why these values are all elevated.

Chi, 30~39 year old female. Ask Date: 2022/06/11

Dr. Hong Yuanbin reply Internal Medicine


Hello, usually a decrease in these values can be concerning.
For example, an increase in anemia is often due to blood becoming too concentrated, which can happen if you have been drinking very little water or losing too much water through sweating, among other rare conditions.
Certain medications can also have these effects, but most cases are benign and do not significantly impact the body.
Overall, I recommend increasing your water intake.
If you experience any discomfort, further examination would be necessary.
Thank you for your question.

Reply Date: 2022/06/11

More Info


When interpreting blood test results, especially during a medical procedure like oocyte freezing, it's essential to understand the significance of each parameter and how they relate to your overall health. In your case, you mentioned elevated levels of hemoglobin (HB), mean corpuscular hemoglobin (MCH), and mean corpuscular volume (MCV). Let's break down these values and their implications.

1. Hemoglobin (HB): Your result of 13.5 g/dL is above the standard range for women, which typically falls between 12.1 to 15.1 g/dL. Elevated hemoglobin levels can indicate several conditions, including dehydration, smoking, or living at high altitudes. In the context of oocyte freezing, it could also suggest that your body is compensating for a lower oxygen supply, which might be due to various factors, including hormonal changes associated with your menstrual cycle.

2. Mean Corpuscular Hemoglobin (MCH): Your MCH level of 31 pg is also elevated compared to the standard range of 27 to 31 pg. MCH measures the average amount of hemoglobin per red blood cell. An elevated MCH can occur in conditions such as macrocytic anemia, where red blood cells are larger than normal, often due to vitamin B12 or folate deficiency. However, in your case, it might simply reflect the higher hemoglobin concentration.

3. Mean Corpuscular Volume (MCV): Your MCV of 92.7 fL is above the normal range of 80 to 100 fL. MCV indicates the average size of red blood cells. Elevated MCV can be associated with macrocytic anemia, liver disease, or hypothyroidism. It can also be influenced by hydration status or the presence of reticulocytes (immature red blood cells) in the bloodstream, which can occur during periods of increased red blood cell production.


Possible Explanations for Elevated Results
- Dehydration: If you were dehydrated at the time of testing, this could lead to a relative increase in hemoglobin and hematocrit levels, as the blood becomes more concentrated.


- Hormonal Changes: The hormonal fluctuations during your menstrual cycle can affect blood parameters. For instance, estrogen can influence red blood cell production and iron metabolism, potentially leading to variations in hemoglobin and related indices.

- Dietary Factors: Your nutritional intake leading up to the test can also play a role. A diet rich in iron or vitamin B12 could contribute to higher hemoglobin levels.

- Physiological Variations: Individual variations in physiology, such as your body’s response to stress or changes in physical activity, can also affect blood test results.


Recommendations
1. Consult Your Doctor: It’s crucial to discuss these results with your healthcare provider, especially since you are undergoing a specific medical procedure. They can provide insights tailored to your health history and current treatment plan.

2. Follow-Up Testing: Depending on your doctor’s assessment, they may recommend follow-up tests to monitor these levels or investigate further if they suspect an underlying condition.

3. Hydration and Nutrition: Ensure you are well-hydrated and maintain a balanced diet, particularly as you prepare for oocyte freezing. This can help stabilize your blood parameters.

4. Monitor Symptoms: Pay attention to any symptoms you may experience, such as fatigue, weakness, or unusual bruising, and report these to your healthcare provider.

In conclusion, while elevated blood test results can be concerning, they often require a comprehensive evaluation in the context of your overall health and specific medical circumstances. Your healthcare provider is the best resource for interpreting these results and guiding you through the oocyte freezing process.

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