Post-Ovulation Risks: Managing Leg Pain After Egg Retrieval - Cardiology

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What are the risks after egg retrieval in assisted reproduction?


On July 5th, after undergoing egg retrieval at the Veterans General Hospital, I was originally supposed to go home and rest.
However, the doctor recommended that I stay in the hospital for a day for observation due to a chocolate cyst on my right ovary.
That night in the hospital, I had no issues with my legs.
After returning home on July 6th, I took the prescribed pain and anti-inflammatory medication before bed.
However, after lying down for 1-2 hours, I woke up with swelling and pain along the right leg, specifically in the groin area, behind the knee, and in the mid-calf region.
Walking to the bathroom alleviated the symptoms, but lying down again for another 1-2 hours would cause the pain to return, forcing me to get up and walk around again to relieve the discomfort.
During the day, I felt fine, and this pattern continued until July 10th.
I suspected it might be a venous embolism, but my leg did not show significant discoloration or swelling.
I also wondered if it could be nerve pain.
Doctor, what do you think about the symptoms I described? Since I was on hormonal medications during the egg retrieval process, I read online that one of the risk factors for venous thrombosis is related to this.
Some suggested I get an ultrasound of my leg, but I was hoping that with regular care, it might improve on its own.
On July 9th, I consulted with a traditional Chinese medicine practitioner who prescribed a formula to promote blood circulation and reduce swelling.
On July 10th, I was able to sleep a bit longer, around 2-3 hours, before waking up in pain again.
However, I am concerned about my sleep quality during the workweek and its impact on my energy levels.
Besides wearing compression stockings and walking more, are there any other methods I can use at home to help reduce the swelling?

Xingxing, 30~39 year old female. Ask Date: 2022/07/10

Dr. Li Han reply Cardiology


Hello, based on your description, "After lying down for 1-2 hours, I woke up due to swelling and pain along the right leg, specifically in the groin area, behind the knee, and around the mid-calf.
Walking to the bathroom alleviated the symptoms, but lying down for another 1-2 hours caused the pain to return, prompting me to get up and walk again for relief...
During the day, there are no issues, and this continued until July 10.
I suspect it may be a venous embolism..." Generally, symptoms of venous obstruction tend to worsen with prolonged standing and are relieved by lying down or elevating the legs, which contradicts your symptoms.
However, since these symptoms occurred during the perioperative period, it would be advisable to consult your gynecologist to see if they have encountered similar cases or if a referral to a relevant specialty for further evaluation is necessary.
The Ministry of Health and Welfare Changhua Hospital is concerned about your well-being.

Reply Date: 2022/07/10

More Info


After undergoing an egg retrieval procedure, it is not uncommon for patients to experience discomfort or pain in the legs, particularly if there are underlying conditions such as a chocolate cyst on the ovary. Your symptoms of pain and swelling in the right leg, especially in the groin, behind the knee, and mid-calf, warrant careful consideration, particularly given the potential risk of venous thromboembolism (VTE) associated with hormonal treatments used during the egg retrieval process.

The discomfort you are experiencing could be attributed to several factors. First, the hormonal medications used during the ovarian stimulation phase can increase the risk of blood clots. This is particularly true for patients with pre-existing conditions, such as a chocolate cyst, which may complicate the situation. The pain that worsens when lying down and improves with movement could suggest venous insufficiency or even the early stages of a clot, but it is essential to note that not all cases present with classic symptoms such as significant swelling or discoloration.

Given your concerns about potential deep vein thrombosis (DVT), it is advisable to seek medical evaluation. An ultrasound of the leg can help rule out the presence of a clot. While you may prefer to manage the symptoms at home, the risk of a serious condition like DVT should not be overlooked. Early detection and treatment are crucial to prevent complications such as pulmonary embolism, which can occur if a clot dislodges and travels to the lungs.

In the meantime, there are several self-care strategies you can implement to help alleviate your symptoms:
1. Compression Stockings: Wearing graduated compression stockings can help improve venous return and reduce swelling. Ensure they fit properly and are worn consistently, especially during periods of inactivity.

2. Hydration: Staying well-hydrated can help maintain blood viscosity and reduce the risk of clot formation. Aim to drink plenty of fluids throughout the day.

3. Movement: As you have already noted, walking helps relieve your symptoms. Try to incorporate regular short walks into your day, especially if you find that prolonged sitting or lying down exacerbates your pain.

4. Elevation: When resting, elevate your legs to help reduce swelling. Use pillows to prop your legs up while lying down.

5. Heat Therapy: Applying a warm compress to the affected areas may help alleviate pain and discomfort. However, be cautious not to apply heat if there is significant swelling or if you suspect a clot.

6. Pain Management: Continue to take any prescribed pain relief medications as directed. Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) can also help manage pain and inflammation, but consult with your healthcare provider before taking them.

7. Monitoring Symptoms: Keep a close watch on your symptoms. If you notice any changes, such as increased swelling, redness, warmth, or if you develop shortness of breath or chest pain, seek immediate medical attention.

While it is understandable to want to manage your symptoms at home, do not hesitate to reach out to your healthcare provider for further evaluation. They can provide guidance tailored to your specific situation and ensure that any potential complications are addressed promptly. Your health and safety should always be the priority, especially after a procedure that can carry risks.

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