Managing Breakouts While Using Tretinoin: What You Need to Know - Dermatology

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Apply topical retinoic acid?


Hello Doctor: I recently visited a dermatologist who prescribed me Tretinoin 0.05% topical cream.
I've been applying it every night before bed, but after a week, I've started to develop a lot of acne on my chin.
Should I continue using it in this situation, or should I change the frequency of application? Will the acne continue to worsen? Thank you for your response.

Mi, 20~29 year old female. Ask Date: 2022/07/22

Dr. Wu Yuxin reply Dermatology


You should consult your attending physician about this issue, as they are the most familiar with your condition.

Reply Date: 2022/07/22

More Info


Managing breakouts while using Tretinoin can be a challenging experience, especially for those new to this topical retinoid. Tretinoin, a derivative of vitamin A, is widely used for treating acne, photoaging, and other skin conditions due to its ability to promote cell turnover and prevent clogged pores. However, it is not uncommon for users to experience an initial worsening of acne, often referred to as "purging," during the first few weeks of treatment.

When you start using Tretinoin, it accelerates the skin's natural exfoliation process. This can lead to the surfacing of existing comedones (clogged pores) and other impurities, resulting in breakouts. This purging phase can last anywhere from a few weeks to a couple of months, depending on individual skin types and conditions. It is essential to understand that this initial breakout does not necessarily indicate that the treatment is ineffective; rather, it is often a sign that the medication is working to clear the skin.

In your case, since you have been using Tretinoin 0.05% for a week and are experiencing an increase in breakouts on your chin, it is crucial to assess a few factors before deciding to continue or adjust your regimen:
1. Duration of Use: One week is relatively early in the treatment process. Many dermatologists recommend giving Tretinoin at least 4 to 6 weeks before making significant changes to your routine, as the skin may still be adjusting to the medication.

2. Application Frequency: If the breakouts are bothersome, you might consider reducing the frequency of application. Instead of using it every night, you could start applying it every other night or even two to three times a week. This can help your skin acclimate to the medication while minimizing irritation.

3. Moisturization: Tretinoin can be drying and irritating, especially in the initial stages. Ensure you are using a gentle, non-comedogenic moisturizer to help maintain skin hydration and reduce irritation. Applying moisturizer before Tretinoin (the "sandwich method") can also help mitigate dryness.

4. Cleansing Routine: Use a mild, non-irritating cleanser to avoid exacerbating any irritation or breakouts. Avoid harsh scrubs or exfoliants, as these can further irritate the skin.

5. Patience and Consistency: It is essential to be patient and consistent with your treatment. Many users find that their skin improves significantly after the initial purging phase. If the breakouts persist beyond a few weeks or worsen significantly, it may be worth consulting your dermatologist for further advice.

6. Avoiding Other Irritants: While using Tretinoin, it is advisable to avoid other potentially irritating products, such as those containing alpha hydroxy acids (AHAs), beta hydroxy acids (BHAs), or other retinoids, as these can increase the likelihood of irritation and breakouts.

In summary, while experiencing breakouts during the initial phase of Tretinoin treatment can be frustrating, it is often a normal part of the process. Adjusting the frequency of application, ensuring proper moisturization, and being patient can help manage this phase. If you have concerns or if the situation does not improve, do not hesitate to reach out to your dermatologist for personalized guidance. They can provide tailored advice based on your specific skin type and condition, ensuring you achieve the best possible results from your treatment.

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