Recurrence of Genital Warts and Treatment Options - Urology

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Phenylephrine recurrence


Hello Doctor, I developed several white bumps on my foreskin at the beginning of this year.
I initially thought they were just pimples and didn't pay much attention to them.
By May, these bumps had neither disappeared nor grown larger; they were also not painful or itchy.
I later consulted a doctor who diagnosed them as molluscum contagiosum, but he suspected that the area at the tip of the foreskin might be genital warts.
I was scheduled for electrosurgery, and recently the wounds have healed, and I received my first dose of the HPV vaccine.
However, I noticed similar bumps appearing near the electrosurgery site for the suspected genital warts.
When I returned to the doctor, he said they didn't look like warts and advised me to observe them further.

I have a few questions:
Q1: Is this a recurrence of genital warts? If not, what could it be?
Q2: I purchased Podofilox to remove them, but after using it, I didn't feel any significant effects; there was no pain or itching, and the bumps don't seem to have diminished.
Could it be that they are not warts, which is why there was no reaction?
Q3: After using Podofilox, I developed bumps near the urethral opening that look very much like acne.
Is this a side effect of using Podofilox? Should I stop using it or continue?
Thank you for your assistance, Doctor.

Min, 20~29 year old female. Ask Date: 2022/07/24

Dr. Li Xinyi reply Urology


The doctor who examined you has indicated that it does not appear to be a recurrence of warts, and we should prioritize their assessment.
If it is not warts and you have used phenol, that would not be appropriate, and side effects could potentially occur.
It is essential to return to the original clinic for a thorough examination and to discuss your situation further with the doctor.

Reply Date: 2022/07/24

More Info


Understanding the recurrence of genital warts, also known as condylomata acuminata, and the treatment options available is crucial for managing this condition effectively. Based on your description, it seems you have been diagnosed with molluscum contagiosum and possibly genital warts. Here’s a detailed response to your questions:
Q1: Is this a recurrence of genital warts? If not, what is it?
The lesions you are observing could potentially be a recurrence of genital warts, especially if they are similar in appearance to the initial lesions. However, it is also possible that they are unrelated conditions, such as sebaceous cysts or other benign skin lesions. The fact that your doctor has advised you to observe them suggests that they may not exhibit the typical characteristics of warts, which are usually raised, cauliflower-like, and can be itchy or painful. It’s important to follow up with your healthcare provider for a definitive diagnosis, as they may recommend further examination or a biopsy if the lesions persist or change in appearance.

Q2: I purchased phenol solution to remove them, but there’s no significant reaction. Does this mean they are not warts?
Phenol solution is a chemical agent used to treat warts and other skin lesions. If you applied it and did not experience any pain, itching, or noticeable change in the lesions, it could indicate that they are not warts. Warts typically respond to treatment with some degree of irritation or discomfort. However, the effectiveness of phenol can vary based on the type of lesion and its depth. If the lesions do not respond to phenol, it may be wise to consult your healthcare provider for alternative treatments or further evaluation.

Q3: After using phenol, I developed what looks like acne near the urethra. Is this a side effect of the phenol? Should I continue or stop using it?
The appearance of new lesions resembling acne after using phenol could be a reaction to the treatment or an unrelated issue. Chemical agents like phenol can sometimes irritate the skin, leading to inflammation or the development of new lesions. However, it is also possible that these are simply coincidental and not directly related to the phenol application. If you are experiencing discomfort or if the new lesions persist, it is advisable to stop using the phenol and consult your healthcare provider for guidance. They can assess the new lesions and determine the best course of action.

Additional Considerations:
1. Follow-Up Care: Regular follow-ups with your healthcare provider are essential for monitoring the condition and ensuring that any new lesions are evaluated promptly.

2. HPV Vaccination: You mentioned receiving the HPV vaccine, which is an important step in preventing future infections. Completing the vaccination series is crucial for optimal protection against HPV strains that cause genital warts and other HPV-related diseases.

3. Safe Practices: Engaging in safe sexual practices, including the use of condoms, can help reduce the risk of transmitting HPV and other sexually transmitted infections (STIs).

4. Treatment Options: If the lesions are confirmed to be genital warts, various treatment options are available, including topical treatments (like imiquimod or podofilox), cryotherapy, laser therapy, and surgical removal. Your healthcare provider can help determine the most appropriate treatment based on your specific situation.

In conclusion, it is essential to maintain open communication with your healthcare provider regarding any changes in your condition. They can provide personalized advice and treatment options based on a thorough evaluation of your symptoms.

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