Is It Safe to Use Neomycin Ointment During Pregnancy?

Used Lifu ointment at 11 weeks of pregnancy?

Hello, doctor.
Today, I applied a common ointment at home called "Lifuh Ointment" on a skin abrasion.
It contains Neomycin Sulfate 5 mg and Bacitracin Zinc 12.5 mg.
I only used a small amount, about the size of a grain of rice, but I would like to consult with you if I can continue using this ointment in the future.

Ivy, 20~29 year old female. Ask Date: 2022/07/28

Dr. Cao Guotao reply Obstetrics and Gynecology

Hello, you can continue to use it.
Wishing you good health.

Reply Date: 2022/07/28

More Info

When it comes to the safety of using Neomycin Ointment during pregnancy, it is essential to consider the potential risks associated with its active ingredients. Neomycin is classified as a Category D drug by the FDA, which means that there is evidence of risk to the human fetus based on human data, but it may be prescribed in certain situations where the benefits outweigh the risks. Bacitracin, on the other hand, is classified as Category C, indicating that animal reproduction studies have shown an adverse effect on the fetus, but there are no adequate and well-controlled studies in pregnant women.
In your case, applying a small amount of Neomycin Ointment (about the size of a grain of rice) is unlikely to cause significant harm, especially if it is a one-time application. The systemic absorption of topical medications is generally low, particularly when applied to intact skin. However, if the skin is broken or compromised, there is a potential for increased absorption, which could raise concerns.
It’s important to note that while Neomycin is effective as a topical antibiotic, its use during pregnancy should be approached with caution. If you have any underlying conditions or if the area of application is extensive, it would be prudent to consult your healthcare provider for personalized advice.
Regarding the use of Bacitracin, while it is generally considered safer than Neomycin, it is still essential to use it judiciously during pregnancy. The risk of potential adverse effects on the fetus cannot be entirely ruled out, and thus, it is advisable to limit its use unless absolutely necessary.

If you are considering using Neomycin Ointment again in the future, it would be wise to discuss this with your healthcare provider. They can provide guidance based on your specific medical history and the condition being treated. Additionally, they may suggest alternative treatments that are safer during pregnancy, especially if you have concerns about the potential risks associated with Neomycin.

In summary, while a one-time application of Neomycin Ointment in a small amount is unlikely to pose a significant risk, it is crucial to weigh the benefits against the potential risks. Always consult with your healthcare provider before using any medication during pregnancy to ensure the safety of both you and your developing baby.

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