Recurrence of Depression
I have been taking medication for depression for 10 years, consistently attending follow-up appointments and adhering to my medication regimen (without any dosage reductions or discontinuations).
However, in the past two years, I have experienced three relapses of depression, and my medication has increased.
From the end of June to the end of July, my medication was adjusted twice.
Currently, I am taking 30 mg of Venlafaxine in the morning and at bedtime, one tablet of Quetiapine at bedtime, one tablet of Zolpidem at bedtime, one tablet of Buspirone, and a quarter of a 15 mg Lurasidone tablet.
I still feel unable to be happy and have lost interest.
I would like to know if incorporating Traditional Chinese Medicine could help reduce the likelihood of relapse or allow for a reduction in medication.
In addition to my depression medication, I am also being treated for ankylosing spondylitis and vitiligo, for which I am taking Hydroxychloroquine 200 mg.
I noticed that the side effects listed on the medication label include emotional instability.
Could this medication affect my depression? Should I consider switching medications?
lynn, 40~49 year old female. Ask Date: 2022/08/04
Dr. Qiu Junda reply Psychiatry
Hello.
In addition to medication, it is best to incorporate non-pharmacological support in the treatment of depression.
Simply put, engaging in leisure activities regularly can help prevent excessive boredom and distress in daily life.
It is commendable that you have been consistently attending follow-up appointments and taking your medication.
You can discuss feasible non-pharmacological options with your physician.
As for traditional Chinese medicine, it is not my area of expertise, so I cannot answer questions about it.
However, I personally believe that if the costs are not too high, trying an additional approach (such as traditional Chinese medicine) could be beneficial.
Regarding the side effects of medication for ankylosing spondylitis, you should consult your physician during your follow-up visit and inform them of your condition.
The physician will take this into consideration when evaluating whether a change in medication is necessary.
Thank you.
Reply Date: 2022/08/04
More Info
Managing depression, especially after a long history of treatment, can be a complex and challenging process. Your experience of having taken antidepressants for a decade, coupled with recent relapses, highlights the need for a comprehensive approach to treatment. Here’s a detailed exploration of your situation, including the potential role of alternative treatments, the impact of your current medications, and considerations for managing your condition.
Understanding Your Current Medication Regimen
You mentioned that you are currently taking a combination of medications, including Venlafaxine (萬憂停), Zolpidem (舒眠諾思), Buspirone (悠然), and Rivastigmine (煩多閃), among others. Each of these medications serves a specific purpose in managing symptoms of depression and anxiety, but they can also have side effects that may complicate your treatment.
1. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that can be effective for depression but may cause side effects such as increased blood pressure, nausea, and withdrawal symptoms if discontinued abruptly.
2. Zolpidem is primarily used for insomnia and can lead to dependency if used long-term. It may not directly address your depressive symptoms.
3. Buspirone is an anxiolytic that can help with anxiety but may take several weeks to show effects.
4. Rivastigmine is typically used for dementia but may have off-label uses. Its impact on mood can vary.
The Role of Hydroxychloroquine
You also mentioned taking Hydroxychloroquine for ankylosing spondylitis and vitiligo. This medication can indeed have side effects, including mood changes and emotional instability. It’s essential to discuss with your healthcare provider whether this medication could be contributing to your depressive symptoms. If it is deemed a significant factor, your doctor may consider adjusting your treatment plan.
Exploring Alternative Treatments
Given your history of recurrent depression, exploring alternative treatments may be beneficial. Integrating complementary therapies can enhance your overall treatment plan. Here are some options to consider:
1. Psychotherapy: Cognitive Behavioral Therapy (CBT) or other forms of therapy can provide tools to manage depression and anxiety. Therapy can help address underlying issues that medications alone may not resolve.
2. Mindfulness and Meditation: Practices such as mindfulness meditation can help reduce symptoms of anxiety and depression. They promote relaxation and can improve emotional regulation.
3. Exercise: Regular physical activity has been shown to have a significant positive effect on mood and can be as effective as medication for some individuals.
4. Diet and Nutrition: A balanced diet rich in omega-3 fatty acids, whole grains, and vegetables can support mental health. Some studies suggest that certain dietary changes may help reduce depressive symptoms.
5. Acupuncture and Traditional Chinese Medicine: Some individuals find relief from depression symptoms through acupuncture or herbal remedies. However, it’s crucial to consult with a qualified practitioner and inform your primary care physician about any alternative treatments you pursue.
Medication Management and Consultation
Given the complexity of your situation, it’s crucial to maintain open communication with your healthcare provider. Here are some steps you can take:
- Regular Follow-ups: Schedule regular appointments to discuss your symptoms and any side effects you may be experiencing. This will allow your doctor to adjust your medication as needed.
- Medication Review: Ask your doctor to review all your medications, including Hydroxychloroquine, to assess their impact on your mood and overall health.
- Consider a Psychiatrist: If you haven’t already, consider consulting a psychiatrist who specializes in mood disorders. They can provide insights into medication management and alternative treatments.
- Monitor Symptoms: Keep a journal of your symptoms, medication side effects, and any changes in your mood. This information can be invaluable during your consultations.
Conclusion
Managing depression, especially with a history of relapses, requires a multifaceted approach that includes medication, therapy, lifestyle changes, and possibly alternative treatments. It’s essential to work closely with your healthcare provider to tailor a treatment plan that addresses your unique needs and circumstances. By exploring all available options and maintaining open communication with your medical team, you can enhance your chances of achieving better mental health and reducing the frequency of relapses.
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