Breakthrough Bleeding While Taking Menstrual Delay Medication - Obstetrics and Gynecology

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Bleeding occurred before completing the course of the medication?


Hello, Doctor.
I took the menstrual delay medication, Medroxyprogesterone, from June 21 to 26, and my period came on June 28 to 30 (just one day later than my original cycle to avoid an exam).
According to my cycle, I was supposed to have my period on July 31, but it still hadn't arrived by August 8.
I visited a gynecology clinic and asked the doctor for assistance to avoid the period from August 16 to 19.
The doctor performed an ultrasound and explained that since there wasn't enough time to induce menstruation, they recommended delaying it.
Therefore, starting from August 8, I took the prescribed medication daily at a fixed time until August 19.
However, on the seventh day of taking the medication (today, August 15), I suddenly experienced light bleeding and menstrual cramps (similar to the feeling on the first day of my period).
Since I am currently out and the clinic is not open today, I would like to ask if this situation is normal and whether I should continue taking the medication (as I still hope to avoid August 16 to 19).
Thank you!

Yun, 20~29 year old female. Ask Date: 2022/08/15

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, continue taking the medication as prescribed and monitor your condition.
Since you have been on the medication for a long time, it may not be effective in controlling your symptoms.
Just keep taking the medication until it's finished and see how it goes.
Wishing you good health.

Reply Date: 2022/08/15

More Info


Breakthrough bleeding while taking menstrual delay medication can be concerning, but it is not uncommon. Medications designed to delay menstruation, such as the one you mentioned (美婷娜, or Medroxyprogesterone), can sometimes lead to unexpected side effects, including breakthrough bleeding. This bleeding can occur due to hormonal fluctuations as your body adjusts to the medication.

When you take hormonal medications, they work by altering the natural hormonal balance in your body. In your case, since you started taking the medication on August 8 and experienced breakthrough bleeding on August 15, it is possible that your body is responding to the hormonal changes induced by the medication. Breakthrough bleeding can manifest as light spotting or bleeding that occurs between periods, and it can be accompanied by cramping or discomfort similar to menstrual pain.

In terms of whether you should continue taking the medication, it is generally advisable to follow your healthcare provider's instructions. Since your doctor recommended continuing the medication until August 19, it would be prudent to do so unless you experience heavy bleeding or severe discomfort. If the bleeding is light and manageable, it may be a sign that your body is adjusting to the medication, and continuing it could help you achieve your goal of delaying your period.

However, if the bleeding becomes heavier or if you experience significant pain, it would be wise to seek medical attention. Since you mentioned that your clinic was closed on the day you experienced the bleeding, consider reaching out to them as soon as they reopen or consult another healthcare provider if necessary. They can provide guidance based on your specific situation and may suggest alternative options if needed.

Additionally, it is important to keep in mind that while breakthrough bleeding can be a normal side effect, it can also indicate that the medication is not effectively suppressing your menstrual cycle. If you find that breakthrough bleeding occurs frequently or if you have concerns about the effectiveness of the medication, discussing these issues with your healthcare provider is essential. They may consider adjusting your dosage or exploring other medications that may be more suitable for your needs.

In summary, experiencing breakthrough bleeding while taking menstrual delay medication is not unusual, and it often resolves on its own. Continue taking the medication as directed unless advised otherwise by a healthcare professional. If you have any concerns or if the bleeding worsens, do not hesitate to seek medical advice. Your health and comfort are paramount, and your healthcare provider is there to support you through this process.

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