Genital Warts and Circumcision: Treatment and Recurrence - Urology

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Phimosis and circumcision?


Hello, Doctor.
I was diagnosed with genital warts last May and have been using the medication Aldara (imiquimod) prescribed by you for treatment.
During the treatment process, I have managed to eliminate all lesions, but they have recurred after a maximum of two months, and this cycle has repeated for a year.
Since the onset of the condition, the warts have remained small and few in number (at most three), and they have consistently appeared on the foreskin without spreading to other areas.
I would like to ask you: 1.
Given the above situation, would circumcision reduce the recurrence rate? (I plan to continue using Aldara post-surgery and maintain my immune system.) 2.
Since the warts have only concentrated in the same area in the past, if I undergo circumcision, will the virus still remain in the skin, potentially leading to new lesions in other areas? Thank you for your patient response!

Yīshī nín hǎo, 30~39 year old female. Ask Date: 2022/08/21

Dr. Du Shixi reply Urology


Hello: 1.
Will circumcision reduce the recurrence rate in the above situation? (Continuing to use Lede Mei post-surgery and maintaining body immunity) ---》 The chances are low.
2.
Since the lesions have previously concentrated in the same location, will the virus remain in the skin after circumcision and potentially appear in new areas? ---》 It is possible.
Wishing you good health, and please practice safe sex.

Reply Date: 2022/08/21

More Info


Genital warts, caused by certain strains of the human papillomavirus (HPV), can be a persistent and frustrating condition for many individuals. Your experience with recurrent warts despite treatment with topical medications like imiquimod (the active ingredient in "樂得美") is not uncommon. The recurrence of genital warts can be attributed to several factors, including the immune response of the individual, the specific HPV strain involved, and the effectiveness of the treatment regimen.

1. Circumcision and Recurrence Rates: Circumcision may potentially reduce the recurrence rate of genital warts, particularly if the warts are localized to the foreskin area. By removing the foreskin, you eliminate the area where the virus can persist and potentially cause new warts to develop. However, it is important to note that circumcision does not guarantee that the virus will not recur in other areas of the genital region. The HPV virus can remain dormant in the skin cells, and even after the warts are removed, the virus may still be present in the body. Therefore, while circumcision may help reduce the likelihood of recurrence in the area where the warts were previously located, it does not eliminate the risk of new warts developing elsewhere.

2. Persistence of the Virus: After circumcision, the HPV virus can still reside in the skin cells of the genital area, including the shaft of the penis or other surrounding tissues. This means that even with the removal of the foreskin, there is still a possibility for new warts to develop in other areas if the virus is still present. The immune system plays a crucial role in controlling the virus, and maintaining a healthy immune response is essential for managing HPV infections. Continuing to use topical treatments like imiquimod post-surgery may help in managing any residual warts or preventing new ones from forming, but it is also vital to support your immune system through a healthy lifestyle, including proper nutrition, regular exercise, and adequate sleep.

In addition to surgical options, there are other treatments available for genital warts, including cryotherapy, laser therapy, and surgical excision. Each treatment has its own benefits and risks, and the choice of treatment should be made in consultation with a healthcare provider who can assess your specific situation and preferences.

It's also important to consider that HPV is a sexually transmitted infection, and engaging in safe sex practices can help reduce the risk of transmission to partners. Vaccination against HPV is also an effective preventive measure, particularly for strains that cause genital warts and cervical cancer.

In summary, while circumcision may reduce the recurrence of genital warts in the area of the foreskin, it does not eliminate the virus from the body or prevent new warts from developing in other areas. Ongoing treatment and a strong immune response are key factors in managing this condition. Always consult with your healthcare provider to discuss the best treatment options for your specific case and to address any concerns you may have regarding HPV and genital warts.

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