Myocardial Perfusion Imaging: Insights for Heart Health - Cardiology

Share to:

Consultation for Myocardial Perfusion Imaging Report


Hello Dr.
Wu, I hope you don't mind me asking about my mother's heart examination.
Recently, she has been feeling very short of breath during exercise and when climbing stairs.
On August 22, I took her to the hospital for a myocardial perfusion imaging (MPI) test, and the report is as follows...
NUCLEAR MEDICINE STUDY: Thallium-201 EKG-gated myocardial perfusion imaging (MPI), with dipyridamole and resting phases.

INDICATION: Diagnosis of coronary artery disease.

CLINICAL HISTORY:
- Symptoms: exertional dyspnea.

- Cardiovascular risk factors: hypertension, hyperlipidemia.

- Previous cardiac examinations: Cardiac echocardiogram (August 10, 2022) revealed preserved left ventricular (LV) contractility.

RADIOPHARMACEUTICAL: Intravenous 2 mCi Tl-201
SCINTIGRAPHIC FINDINGS:
* Thallium-201 myocardial perfusion imaging with EKG-gated SPECT was performed after a standardized dipyridamole stress protocol (dipyridamole: 0.56 mg/kg, continuous IV push over 4 minutes; and aminophylline 50 mg IV infusion for symptom relief), followed by a resting state.

* Dizziness was noted during stress, which gradually improved after aminophylline injection.

* No chest pain or significant ST-T changes were observed during stress.

* The initial and 4-hour delayed images showed (1) a mildly reversible perfusion defect at the apex, anteroseptal, inferior, and basal inferolateral walls, (2) transient LV dilation and normal lung uptake after stress (Lung/Heart ratio, stress/resting: 0.31/0.39).

* Gated SPECT (8 frames per cardiac cycle, estimated by QGS method):
- Post-stress LVEF = 75%; resting LVEF = 74%.

- Post-stress LV EDV = 53 ml, ESV = 13 ml; resting LV EDV = 45 ml, ESV = 12 ml.

- Regional wall motion: no definite regional wall motion abnormalities.

Impression: Under standardized dipyridamole stress testing, (1) probably mild inducible ischemia at the apex, anteroseptal, inferior, and basal inferolateral walls, (2) good LV contractility, stress-induced LV dysfunction.
Blood test results: Total cholesterol 217, triglycerides 262.
Currently, the hospital has prescribed my mother medication including Metoprolol 5 mg and Warfarin 10/20 mg.
I would like to consult whether the myocardial perfusion imaging indicates that my mother's heart function is normal, if there is a risk of myocardial infarction, and if there are any precautions or further examinations needed.
Thank you very much for your explanation, Dr.
Wu.

Best regards,
Andy
August 23, 2022

Yan Fengteng, 40~49 year old female. Ask Date: 2022/08/23

Dr. Wu Xueming reply Cardiology


The report indicates mild myocardial hypoxia.
Please manage your blood pressure and lipid levels carefully.
If you continue to experience frequent chest pain or discomfort, please discuss with your physician whether a cardiac catheterization is necessary.

Reply Date: 2022/08/23

More Info


Understanding myocardial perfusion imaging (MPI) is crucial for assessing heart health, particularly in patients with symptoms like exertional dyspnea, as seen in your mother's case. The report you provided indicates that a Thallium-201 EKG-gated MPI was performed after a dipyridamole stress test, which is a common method used to evaluate coronary artery disease (CAD) and myocardial ischemia.


Key Findings from the Report:
1. Clinical History: Your mother has a history of hypertension and hyperlipidemia, which are significant risk factors for coronary artery disease. The presence of exertional dyspnea (shortness of breath during activity) raises concerns about potential ischemic heart disease.

2. Scintigraphic Findings:
- The imaging revealed mildly reversible perfusion defects at several locations in the heart: the apex, anteroseptal, inferior, and basal inferolateral walls. This suggests that there may be areas of the heart muscle that are not receiving adequate blood flow during stress, which could indicate ischemia.

- The report also noted transient left ventricular (LV) dilatation during stress, which can occur when the heart is under increased workload and may indicate stress-induced dysfunction.

- Importantly, the LVEF (Left Ventricular Ejection Fraction) was reported as 75% during stress and 74% at rest, indicating preserved LV function. This is a positive sign, as it suggests that the heart is still capable of pumping effectively despite the observed perfusion defects.

3. Lung Uptake: The lung-to-heart ratios were normal, which is a good indicator that there is no significant congestion or heart failure at the time of the test.


Interpretation of Results:
The findings suggest that while there are areas of the heart that may not be receiving enough blood flow under stress (inducible ischemia), the overall function of the heart remains good. The absence of significant wall motion abnormalities further supports that there is no severe damage to the heart muscle at this time.


Risk of Myocardial Infarction:
While the report does not indicate any acute myocardial infarction (heart attack), the presence of inducible ischemia does raise concerns about the risk of future cardiac events. The reversible nature of the defects suggests that the ischemia is not permanent, but it is still essential to address the underlying risk factors, such as hypertension and hyperlipidemia, to prevent progression to more severe coronary artery disease.


Recommendations:
1. Follow-Up with a Cardiologist: It is crucial for your mother to discuss these findings with her cardiologist. They may recommend further testing, such as a coronary angiogram, to assess the severity of any blockages in the coronary arteries.

2. Medication Management: The medications your mother is currently taking (脈優5mg and 維妥力錠) should be reviewed by her healthcare provider to ensure they are appropriate for managing her risk factors.

3. Lifestyle Modifications: Encourage your mother to adopt heart-healthy lifestyle changes, including a balanced diet low in saturated fats and cholesterol, regular physical activity as tolerated, smoking cessation if applicable, and weight management.

4. Monitoring Symptoms: Keep track of any changes in symptoms, such as increased shortness of breath, chest pain, or fatigue, and report these to her healthcare provider promptly.

In summary, while your mother's heart function appears to be preserved, the presence of inducible ischemia warrants careful monitoring and management of her cardiovascular risk factors to reduce the risk of future cardiac events. Regular follow-ups with her healthcare provider will be essential in ensuring her heart health.

Similar Q&A

Understanding Myocardial Perfusion Imaging: A Case Study of Ischemic Heart Disease

HISTORY: A 28-year-old male (80 kg) presents with recent chest tightness and has been referred for the detection of ischemic heart disease. TECHNIQUE: Following the intravenous injection of 2 mCi of Tl-201 Chloride after the administration of dipyridamole (Persantin) at a dose ...


Dr. He Dongjin reply Cardiology
Hello, there should be no issues; just observe and take care. Changhua Hospital is concerned about you.

[Read More] Understanding Myocardial Perfusion Imaging: A Case Study of Ischemic Heart Disease


Understanding Myocardial Perfusion Scan Results in Coronary Artery Disease

Examination Item: Tl-201 Myocardial Perfusion Scan 1. Stress Imaging: The stress imaging following intravenous infusion of dipyridamole and the post-dipyridamole SPECT images revealed moderate hypoperfusion over the apical septo-anterior and septal walls of the left ventricle (e...


Dr. Huang Yinghe reply Cardiology
Hello: The nuclear medicine examination shows moderate myocardial perfusion reduction, and the exercise electrocardiogram is also positive, indicating a certain degree of myocardial hypoxia, commonly associated with coronary artery stenosis (but these two tests cannot definitivel...

[Read More] Understanding Myocardial Perfusion Scan Results in Coronary Artery Disease


Understanding Cardiac Perfusion Imaging: Insights and Recommendations

Hello, Doctor. In 2021, I experienced chest tightness and palpitations, with my heart rate usually slightly elevated at 90-100 beats per minute, so I sought treatment at Taichung Cheng Ching Hospital. The physician ordered a myocardial perfusion imaging test, but did not provide ...


Dr. He Dongjin reply Cardiology
Hello, mild perfusion abnormalities indicate that it's not serious. You can just take medication and observe, so there's no need to worry. Changhua Hospital cares about you.

[Read More] Understanding Cardiac Perfusion Imaging: Insights and Recommendations


Understanding Myocardial Perfusion Issues: Insights and Management Strategies

Examination Date: 2023/08/21 16:09:45 Examination Summary: 26025: Stress & Redistribution Myocardial Perfusion Study with SPECT Report Content: History: Chest tightness or pain (+), Dyspnea on exertion (-), EKG (+) inferior QS. Unable to perform treadmill exercise test ...


Dr. He Dongjin reply Cardiology
Hello, a report indicating mild hypoxia usually does not indicate a serious issue and should be monitored. Changhua Hospital cares about you.

[Read More] Understanding Myocardial Perfusion Issues: Insights and Management Strategies


Related FAQ

Myocardial Perfusion Imaging

(Cardiology)

Myocardial Perfusion Scan

(Cardiology)

Echocardiogram

(Cardiology)

Myocardial Hypoxia

(Cardiology)

Pulse

(Cardiology)

Chf

(Cardiology)

Angina

(Cardiology)

Breathing

(Cardiology)

Cardiac Catheterization

(Cardiology)

Pacs

(Cardiology)